Rchr
J-GLOBAL ID：200901018743860629   Update date: Apr. 10, 2024

Ishigaki Hirohito

イシガキ ヒロヒト | Ishigaki Hirohito
Affiliation and department：
Shiga University of Medical Science

About Shiga University of Medical Science


Job title： Associate Professors
Research field  (4)： Internal medicine - General ,  Immunology ,  Immunology ,  Experimental pathology
Research keywords  (6)： immunology ,  internal medicine ,  pathology ,  cancer immunology ,  regenerative medicine ,  iPSCs
Research theme for competitive and other funds  (11)：
  • 2024 - 2027 霊長類モデルを用いた末梢血IL-6産生細胞の特徴と免疫記憶に与える影響の解析
  • 2019 - 2022 Study on molecular mechanism of collagen-induced arthritis in cynomolgus monkeys
  • 2019 - 2022 Development of diagnosis and therapy for aging using a nonhuman primate model of premature aging
  • 2019 - 2022 Mechanism of plasma membrane expression of endoplasmic reticulum chaperone proteins
  • 2017 - 2020 Clinicopathological and molecular pathological differentiation between fundic gland polyp and fundic gland polyp-like lesion of the stomach
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Papers (71)：
  • Cong Thanh Nguyen, Misako Nakayama, Hirohito Ishigaki, Yoshinori Kitagawa, Akemi Kakino, Marumi Ohno, Masashi Shingai, Yasuhiko Suzuki, Tatsuya Sawamura, Hiroshi Kida, et al. Increased expression of CD38 on endothelial cells in SARS-CoV-2 infection in cynomolgus macaque. Virology. 2024. 594. 110052-110052
  • Hirohito Ishigaki, Sayaka Ito, Takako Sasamura, Hideaki Ishida, Misako Nakayama, Cong Thanh Nguyen, Takaaki Kinoshita, Shingo Suzuki, Chizuru Iwatani, Hideaki Tsuchiya, et al. MHC-DRB alleles with amino acids Val11, Phe13, and the shared epitopes promote collagen-induced arthritis and a rapid IgG1 response in Filipino cynomolgus macaques. HLA. 2024. 103. 1. e15316
  • Shino Shimizu, Misako Nakayama, Cong Thanh Nguyen, Hirohito Ishigaki, Yoshinori Kitagawa, Fumihiko Yasui, Yoshiki Yagi, Tomoe Kusayanagi, Michinori Kohara, Yasushi Itoh, et al. SARS-CoV-2 induces inflammation and intracranial infection through the olfactory epithelium-olfactory bulb pathway in non-human primates. Journal of Neuroimmunology. 2024. 387. 578288-578288
  • Eri Kawakami, Norikazu Saiki, Yosuke Yoneyama, Chiharu Moriya, Mari Maezawa, Shuntaro Kawamura, Akiko Kinebuchi, Tamaki Kono, Masaaki Funata, Ayaka Sakoda, et al. Complement factor D targeting protects endotheliopathy in organoid and monkey models of COVID-19. Cell stem cell. 2023. 30. 10. 1315-1330
  • 清水 志乃, 仲山 美沙子, 石垣 宏仁, Nguyen Thanh Cong, 北川 善紀, 伊藤 靖, 清水 猛史. 「感染・免疫研究の新潮流」 非ヒト霊長類の嗅上皮から嗅球におけるSARS-CoV-2感染の病態. 日本耳鼻咽喉科免疫アレルギー感染症学会抄録集. 2023. 3回. 84-84
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MISC (111)：
  • 石垣 宏仁. 動物MHC研究の新展開:医学や種の保存への応用を目指して カニクイザルCIAモデルの特徴とCIA感受性MHC-DRBアレルの同定. MHC: Major Histocompatibility Complex. 2023. 30. 2Suppl. 49-49
  • 大村 寧, 高木 彩乃, 小杉 和希, 鍬田 菜摘, 西村 公宏, 石垣 宏仁, 杉原 洋行. 劇症1型糖尿病様の経過で突然死し,病理解剖を施行した一症例. 糖尿病. 2023. 66. 4. 308-308
  • 塩原 正規, 仲山 美沙子, 石垣 宏仁, 伊藤 靖. インフルエンザ不活化全粒子ワクチンはB細胞の体細胞高頻度突然変異を誘導する。. 日本病理学会会誌. 2023. 112. 1. 242-242
  • 仲山 美沙子, 北川 直子, 石垣 宏仁, Nguyen Thanh Cong, 石田 英明, 鈴木 紗織, 小笠原 一誠, 伊藤 靖. サルにおけるH5N1不活化全粒子ワクチン接種5年後の肺炎予防効果. 日本病理学会会誌. 2023. 112. 1. 242-242
  • 森河 友里, 仲山 美沙子, 笹村 孝子, 石垣 宏仁, 伊藤 靖. 慢性呼吸器疾患患者由来の気道オルガノイドにおけるインフルエンザおよび新型コロナウイルス受容体の発現. 日本病理学会会誌. 2023. 112. 1. 382-382
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Patents (9)：
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Education (2)：
  • 2003 - 2006 Shiga University of Medical Science Faculty of Medicine Ph.D. course student
  • 1994 - 2000 Shiga University of Medical Science Faculty of Medicine
Professional career (1)：
  • 医学博士 (滋賀医科大学)
Work history (7)：
  • 2021/10 - 現在 滋賀医科大学 病理学講座 疾患制御病態学部問 准教授
  • 2022/10 - 2023/03 University of Southern California Department of Surgery Post-doctral fellow
  • 2013/04 - 2021/09 Shiga University of Medical Science, Department of Pathology Branch of Pathology and Disease Regulation lecturer
  • 2008/01 - 2013/03 Departoment of Pathology Branch of Pathology and Disease Regulation assistant professor
  • 2006/04 - 2007/12 Shiga University of Medical Science, Department of Pathology Branch of Pathology and Disease Regulation project assistant professor
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Association Membership(s) (7)：
Japanese association of cancer immunology ,  JAPAN GASTROENTEROLOGICAL ENDOSCOPY SOCIETY ,  JAPANESE SOCIETY OF GASTROENTEROLOGY ,  THE JAPANESE SOCIETY OF INTERNAL MEDICINE ,  THE JAPANESE CANCER ASSOCIATION ,  THE JAPANESE SOCIETY FOR IMMUNOLOGY ,  THE JAPANESE SOCIETY OF PATHOLOGY
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