Rchr
J-GLOBAL ID：200901018806569466
Update date: Feb. 01, 2024
Itoh Toshimasa
イトウ トシマサ | Itoh Toshimasa
Affiliation and department：
Job title：
Associate Professor
Research field (2)：
Pharmaceuticals - chemistry and drug development
, Structural biochemistry
Research keywords (9)：
核内受容体
, NMR-構造解析
, X-線結晶構造解析
, 構造生物学
, 創薬化学
, Drug design
, Fatty Acid
, Nuclear Receptor
, Structural Study
Research theme for competitive and other funds (2)：
- 2018 - 2021 A study of covalent modifier evaluation method using HDX
- 2008 - 2010 Role of ligands for allosteric network of nuclear receptors
Papers (63)：
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Hiroyuki Kojima, Ryota Yanagi, Eri Higuchi, Mami Yoshizawa, Tomoyuki Shimodaira, Misaki Kumagai, Tatsuhiro Kyoya, Miyu Sekine, Daichi Egawa, Nami Ohashi, et al. Covalent Modifier Discovery Using Hydrogen/Deuterium Exchange-Mass Spectrometry. Journal of Medicinal Chemistry. 2023. 66. 7. 4827-4839
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Miyu Sekine, Hiroaki Ishida, Toshimasa Itoh. Synthesis of Triazolo[c]coumarins and Differences in the Fluorescence Properties of Their Isomers. Asian Journal of Organic Chemistry. 2023. 12. 5
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Terushi Ito, Chiharu Miwa, Yuki Haga, Makoto Kubo, Toshimasa Itoh, Keiko Yamamoto, Shintaro Mise, Erika Goto, Harunobu Tsuzuki, Chisato Matsumura, et al. Enantioselective metabolism of chiral polychlorinated biphenyl 2,2',3,4,4',5',6-Heptachlorobiphenyl (CB183) by human and rat CYP2B subfamilies. Chemosphere. 2022. 308. Pt 2. 136349-136349
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Hideyuki Inui, Terushi Ito, Chiharu Miwa, Yuki Haga, Makoto Kubo, Toshimasa Itoh, Keiko Yamamoto, Masayuki Miyaoka, Tadashi Mori, Harunobu Tsuzuki, et al. Differences in Enantioselective Hydroxylation of 2,2',3,6-Tetrachlorobiphenyl (CB45) and 2,2',3,4',6-Pentachlorobiphenyl (CB91) by Human and Rat CYP2B Subfamilies. Environmental science & technology. 2022
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Miku Yabu, Yuki Haga, Toshimasa Itoh, Erika Goto, Motoharu Suzuki, Kiyoshi Yamazaki, Shintaro Mise, Keiko Yamamoto, Chisato Matsumura, Takeshi Nakano, et al. Hydroxylation and dechlorination of 3,3',4,4'-tetrachlorobiphenyl (CB77) by rat and human CYP1A1s and critical roles of amino acids composing their substrate-binding cavity. The Science of the total environment. 2022. 837. 155848-155848
ｍore...
Education (5)：
- 1999 - 2002 Tokyo University of Pharmacy and Life Sciences Graduate School of Pharmacy
- - 2002 Tokyo University of Pharmacy and Life Science Graduate School, Division of Pharmaceutical Sciences Pharmacy
- 1997 - 1999 Tokyo University of Pharmacy and Life Sciences Graduate School of Pharmacy
- 1993 - 1997 Tokyo University of Pharmacy and Life Sciences School of Pharmacy School of Pharmacy
- - 1997 Tokyo University of Pharmacy and Life Science Faculty of Pharmaceutical Science Pharmacy
Professional career (1)：
- Doctor (Pharmacy) (Tokyo University of Pharmacy and Life Science)
Work history (6)：
Association Membership(s) (5)：
日本レチノイド研究会
, 日本薬学会
, Japanese Society for Retinoid Research
, The Society of Synthetic Organic Chemistry
, The Pharmaceutical Society of Japan
