Research theme for competitive and other funds (8)：
2020 - 2023 Basic construction for medical treatment of oral cancer by controlling of metal-binding protein expression utilizing optogenetics
2017 - 2020 Foundation of medical treatment for tongue cancer by the regulation of metal-binding protein
2016 - 2019 Elucidation of the osteoclast-derived cytokine-Wnt signaling network responsible for coupling between bone resorption and formation.
2010 - 2012 Elucidation of mechanism of drug-induced gingival overgrowth and search for its therapeutic drugs
2008 - 2010 The functional elucidation of salivary protein histatin toward the development of anti-inflammatory agent
2007 - 2008 Application of Kampo medicine to periodontal disease treatment and clarification of its mechanisms
2005 - 2006 Research on tissues and cell types-specific expression of the histatin 3 gene implicated in innate immune system
2004 - 2006 歯周病の原因解明としての歯肉線維芽細胞のLPSトレランス機構解明
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Papers (50)：
Masanori Koide, Teruhito Yamashita, Kohei Murakami, Shunsuke Uehara, Keigo Nakamura, Midori Nakamura, Mai Matsushita, Toshiaki Ara, Hisataka Yasuda, Josef M. Penninger, et al. Sclerostin expression in trabecular bone is downregulated by osteoclasts. Scientific Reports. 2020. 10. 1
Toshiaki Ara, Masanori Koide, Hiroyuki Kitamura, Norio Sogawa. Effects of shokyo (Zingiberis Rhizoma) and kankyo (Zingiberis Processum Rhizoma) on prostaglandin E2 production in lipopolysaccharide-treated mouse macrophage RAW264.7 cells. PeerJ. 2019. 7. e7725
Toshiaki Ara, Norio Sogawa. Effects of shinbuto and ninjinto on prostaglandin E-2 production in lipopolysaccharide-treated human gingival fibroblasts. PEERJ. 2017. 5
