Maekawa Mamiko

マエカワマミコ | Maekawa Mamiko

Affiliation and department：
Job title： Chiba University

Research field (4)： Developmental biology , Urology , Laboratory animal science , Anatomy

Research keywords (4)：発生生物学 , spermatogenesis , reproductive biology , sex differentiation

Research theme for competitive and other funds (21)：

2022 - 2025 性分化疾患モデルマウスを用いた生殖器分化機構の解析
2013 - 2016 Cellular and molecular studies on expression of sperm functional proteins relating with infertility using gene-modified mouse lines
2012 - 2015 Study for a new measurement for the mammalian sperm oocyte-activation ability
2011 - 2012 Induction of spermatogenic cells from human multipotent stem cell by microinjection into the mouse testis
2010 - 2012 Cellular and molecular study on live imaging of expression of sperm functional proteins and its relation to infertility

2009 - 2011 Applications of a new assay for the function of mammalian sperm centrosome

2007 - 2008 Study on a new assay for the function of mammalian spenn centrosome

2007 - 2008 Molecular-cellular studies on imaging from fertilization to early embryonal development and infertility

2005 - 2006 Analysis of dymanics and function of Sertoli cell intercellular junction

2005 - 2006 Disintegration of spermatozoa : Molecular mechanism of coiled tail and round-head formation

2004 - 2006 Cell-biological analyses on the mechanism of infertility induced in gene knockout mice and sperm preparation leading to oocyte activation.

2002 - 2003 ANALYSES OF SPERM-EGG INTERACTION AND MECHANISM OF INFERTILITY USING INFERTILITY RELATED GENE KNOCKOUT MOUSE

1996 - 1998 Cytochemical study on the substances(ZP1-3, sp56, acrosin)working at mammalian fertilization.

1994 - 1995 Correlation between structure and function of the seminiferous tubule wall and its excurrent duct wall.

1994 - 1994 哺乳類配偶子における同種認識と付着に関与する物質の細胞化学的研究

1992 - 1993 Structure and movements of seminiferous and epididymal tubules. --Movements analyzed by video tape in relation to the muscular elements and innervation--

1991 - 1993 Morphological studies of spermatozoa during capacitation and in relation to attachment mechmism with zona pellucida.

1991 - 1991 精巣特異的熱ショックタンパク質t-hsp70の細胞内局在

1989 - 1991 three-Dimensionally Structural Interaction Between Spermatogenic Cells and Sertoli Cell and Its Cytochemical Investigation.

1987 - 1989 Immunocytochemical and ultrastructural study on the condition of Fertilization.

1986 - 1988 Morphological differentiation of seminiferous epithelium in vitro.

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Papers (8)：

Yayoi Ikeda, Ayako Tagami, Mamiko Maekawa, Akiko Nagai. The conditional deletion of steroidogenic factor 1 (Nr5a1) in Sox9-Cre mice compromises testis differentiation. Scientific Reports. 2021. 11. 1
Anahara R, Toyama Y, Maekawa M, Kai M, Ishino F, Toshimori K, Mori C. Flutamide depresses expression of cortactin in the ectoplasmic specialization between the Sertoli cells and spermatids in the mouse testis. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2006. 44. 7. 1050-1056
Toshimori K, Maekawa M, Ito C, Toyama Y, Suzuki-Toyota F, Saxena D.K. The involvement of immunoglobulin superfamily proteins in spermatogenesis and sperm-egg interaction. Reprod Med Biol. 2006. 5. 2. 87-93
Takahashi T, Tanaka H, Iguchi N, Kitamura K, Chen Y. L, Maekawa M, Nishimura H, Ohta H, Miyagawa Y, Matsumiya K, et al. Rosbin: A novel homeobox-like protein gene expressed exclusively in round spermatids. Biology of Reproduction. 2004. 70. 5. 1485-1492
T NAGANO, M MAEKAWA, Y FUKUDA, T MURAKAMI. MORPHOLOGICAL-STUDIES ON THE WALL COMPONENTS OF SEMINIFEROUS AND EPIDIDYMAL TUBULES IN RODENTS IN RELATION TO THEIR MOVEMENTS. PERSPECTIVES ON ASSISTED REPRODUCTION. 1994. 4. 129-135

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MISC (13)：

Introduction of the Department of Reproductive Biology and Medicine. 2013. 89. 4. 137-142
大和屋健二, 吉田恵一, 伊藤千鶴, 前川眞見子, 柳田光昭, 荒木慶彦, 宮戸健二, 外山芳郎, 鈴木(豊田, 二美枝, et al. MN9抗原Equatorin O型糖鎖は配偶子膜融合に重要である. 解剖学雑誌. 2009. 84. Supplement. 170-170
大和屋健二, 吉田恵一, 伊藤千鶴, 前川眞見子, 柳田光昭, 荒木慶彦, 宮戸健二, 和田邦生, 外山芳郎, 鈴木(豊田, et al. 哺乳類精子MN9抗原EQUATORIN:遺伝子の同定と分子の解析. 解剖学雑誌. 2008. 83. Supplement. 204-204
Kenji Yamatoya, Keiichi Yoshida, Ito Chizuru, Mamiko Maekawa, Mitsuaki Yanagida, Yoshihiko Araki, Kenji Miyado, Yoshiro Toyama, Fumie Suzuki-Toyota, Kiyotaka Toshimori. Mammalian sperm MN9 antigen N-,O-sialoglycoprotein EQUATORIN: Biochemical characterization and identification of the gene. BIOLOGY OF REPRODUCTION. 2008. 218-219
外山芳郎, 多田昇弘, 大和屋健二, 吉田恵一, 和田邦生, 伊藤千鶴, 前川眞見子, 鈴木二美枝, 年森清隆. ICSIに用いるマウス精子の調製法とその形態学的影響. 解剖学雑誌. 2007. 82. Suppl. 206-206

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