SHIRAKAWA HIDEKI

シラカワヒデキ | SHIRAKAWA HIDEKI

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： http://rainbow.pc.uec.ac.jp/

Research field (4)： Clinical pharmacy , Physiology , Cell biology , Biophysics

Research keywords (4)： Bioimaging , Cell Biology , バイオイメージング , 細胞生理学

Research theme for competitive and other funds (12)：

2022 - 2025 生細胞で二次メッセンジャー濃度を自由自在に制御する手法の開発と応用
2015 - 2017 Development of IP3 clamp method
2009 - 2011 Functional coupling between Ca^<2+> influx anf Ca^<2+> release during Ca^<2+> oscillatons in fertilized mammalian eggs
2007 - 2009 Advanced Imaging Method of Light Source Distributions in Biological Tissues
2006 - 2006 生細胞分光イメージングと多変量解析法による多重蛍光の定量的分離解析システムの開発

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Papers (71)：

Ryotaro Kano, Ayaka Tabuchi, Yoshinori Tanaka, Hideki Shirakawa, Daisuke Hoshino, David C Poole, Yutaka Kano. In vivo cytosolic H2O2 changes and Ca2+ homeostasis in mouse skeletal muscle. American journal of physiology. Regulatory, integrative and comparative physiology. 2023
Tabuchi, A, Tanaka, Y, Takagi, R, Shirakawa, H, Shibaguchi, T, Sugiura, T, Poole, D.C, Kano, T. Ryanodine receptors mediate high intracellular Ca²⁺ and some myocyte damage following eccentric contractions in rat fast twitch skeletal muscle. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 2022. 322. 1. R14-R27
Matsu-ura, T, Shirakawa, H, Suzuki, K.G.N, Miyamoto, A, Sugiura, K, Michikawa, T, Kusumi, A, Mikoshiba, K. Dual-FRET imaging of IP₃ and Ca²⁺ revealed Ca²⁺-induced IP₃ production maintains long lasting Ca²⁺ oscillations in fertilized mouse eggs. Scientific Reports. 2019. 9. 1. 4829
Wakizaka, M, Eshima, H, Tanaka, T, Shirakawa, H, Poole, D.C, Kano, Y. In vitro Ca²⁺ dynamics induced by Ca²⁺ injection in individual rat skeletal muscle fibers. Physiological Reports. 2017. 5. 5. e13180
Hideki Shirakawa, Takashi Kikuchi, Masahiko Ito. Calcium Signaling in Mammalian Eggs at Fertilization. CURRENT TOPICS IN MEDICINAL CHEMISTRY. 2016. 16. 24. 2664-2676

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MISC (8)：

ITO MASAHIKO, SHIKANO TOMOHIDE, SHIRAKAWA HIDEKI, AWAJI TAKEO, MIYAZAKI SHUN'ICHI. 哺乳類卵活性化精子蛋白質候補ホスホリパーゼCゼータ細胞内動態および機能解析. 東京女子医科大学総合研究所紀要. 2007. 27. 21-22
SHIRAKAWA HIDEKI, ITO MASAHIKO, MIYAZAKI SHUN'ICHI. FRET型プローブを用いた哺乳類卵細胞内IP3濃度変化の測定. 東京女子医科大学総合研究所紀要. 2006. 26. 20-21
曽根淑恵, 熊切順, 武内裕之, 木下勝之, 伊藤昌彦, 白川英樹, 鹿野朝秀, 宮崎俊一. マウス胚初期発生におけるホスホリパーゼCゼーターの核移行. 日本不妊学会雑誌. 2005. 50. 4. 511-511
伊藤昌彦, 曽根淑恵, 白川英樹, 鹿野朝秀, 宮崎俊一. 卵活性化精子因子候補PLC-ζのマウスはい初期発生における核移行能の解析. 日本発生生物学会大会発表要旨集. 2005. 38th. 198
白川英樹. 多変量解析的手法による蛍光スペクトル成分分離法とその細胞生理学的実験への応用. 日本生理学会雑誌. 2004. 66. 12. 381-390

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Books (3)：

Lectures and oral presentations (79)：

In vivo mitochondrial Ca2+ dynamics during tetanic muscle contraction in male and female mice
(第100回日本生理学会大会 2023)
Regulation of cortical actin dynamics and cytoplasmic flow by intracellular Ca2+ in mouse oocytes
(第100回日本生理学会大会 2023)
In vivo環境下における筋収縮負荷時のマウスミトコンドリア内Ca2+動態の可視化
(第76回日本体力医学会 2022)
The organization and dynamics of cortical actin cytoskeleton regulated by cytosolic Ca2+ in mammalian eggs.
(第99回日本生理学会合同大会 2022)
The organization and dynamics of cortical actin cytoskeleton regulated by cytosolic Ca2+ in mammalian eggs.resumption in mammalian eggs
(第99回日本生理学会合同大会 2022)

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Education (3)：

Professional career (2)：

Work history (5)：

2010/04/01 - The University of Electro-Communications 准教授
2007/04/01 - 2010/03/31 電気通信大学電気通信学部准教授
2005/10/01 - 2007/03/31 The University of Electro-Communications Associate Professor
2002/07/01 - 2005/09/30 Tokyo Women's Medical University Assistant Professor
1991/04/01 - 2002/06/30 Tokyo Women's Medical University Instructor

Committee career (1)：

Association Membership(s) (5)：

日本生理学会 , 日本発生生物学会 , 日本生物物理学会 , Biophysical Society(アメリカ) , 日本動物学会

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