Rchr
J-GLOBAL ID:200901020346358091   Update date: Jan. 31, 2024

HORIE Kuniko

ホリエ クニコ | HORIE Kuniko
Affiliation and department:
Job title: 教授
Homepage URL  (2): http://square.umin.ac.jp/smu-rcgm/index.htmlhttp://square.umin.ac.jp/smu-rcgm/index_eng.html
Research keywords  (8): 眼腫瘍 ,  加齢黄斑変性 ,  卵巣がん ,  子宮内膜がん ,  前立腺がん ,  乳がん ,  アンドロゲン受容体 ,  エストロゲン受容体
Research theme for competitive and other funds  (14):
  • 2023 - 2026 女性がん患者由来モデルを活用した治療抵抗性獲得機構と内分泌・代謝変容の解明と応用
  • 2020 - 2023 ホルモン依存性女性がん患者由来培養・移植系における病態特異的代謝機構の解明と応用
  • 2020 - 2022 Roles of super-enhancers in patient-derived prostate cancer cells and xenografts.
  • 2017 - 2020 患者由来乳がん細胞・移植腫瘍におけるエストロゲン作用ネットワークの解明と臨床応用
  • 2016 - 2018 がん微小環境におけるエクソソーム由来分泌型非コードRNAの機能とその臨床応用
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Papers (82):
  • Ami Kobayashi, Kotaro Azuma, Toshihiko Takeiwa, Toshimori Kitami, Kuniko Horie, Kazuhiro Ikeda, Satoshi Inoue. A FRET-based respirasome assembly screen identifies spleen tyrosine kinase as a target to improve muscle mitochondrial respiration and exercise performance in mice. Nature communications. 2023. 14. 1. 312-312
  • Kenta Yoh, Kazuhiro Ikeda, Kuniko Horie, Satoshi Inoue. Roles of Estrogen, Estrogen Receptors, and Estrogen-Related Receptors in Skeletal Muscle: Regulation of Mitochondrial Function. International journal of molecular sciences. 2023. 24. 3
  • Toshihiko Takeiwa, Kazuhiro Ikeda, Takashi Suzuki, Wataru Sato, Kaori Iino, Yuichi Mitobe, Hidetaka Kawabata, Kuniko Horie, Satoshi Inoue. PSPC1 is a potential prognostic marker for hormone-dependent breast cancer patients and modulates RNA processing of ESR1 and SCFD2. Scientific Reports. 2022. 12. 1
  • Kuniko Horie, Kiyoshi Takagi, Toshihiko Takeiwa, Yuichi Mitobe, Hidetaka Kawabata, Takashi Suzuki, Kazuhiro Ikeda, Satoshi Inoue. Estrogen-Inducible LncRNA BNAT1 Functions as a Modulator for Estrogen Receptor Signaling in Endocrine-Resistant Breast Cancer Cells. Cells. 2022. 11. 22
  • Sachi Kitayama, Kazuhiro Ikeda, Wataru Sato, Hideki Takeshita, Satoru Kawakami, Satoshi Inoue, Kuniko Horie. Testis-expressed gene 11 inhibits cisplatin-induced DNA damage and contributes to chemoresistance in testicular germ cell tumor. Scientific reports. 2022. 12. 1. 18423-18423
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MISC (52):
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Patents (5):
Books (1):
  • 「Analysis of TFRNs Associated with Steroid Hormone-Related Cancers」
    Methods in Molecular Biology 2014
Lectures and oral presentations  (133):
  • EBAG9は細胞外小胞を介する伝達によりがん免疫エスケープと上皮間葉移行を引き起こす
    (第46回日本分子生物学会年会 2023)
  • 核内受容体に制御されるミトコンドリア遺伝子COX7RPは酸素呼吸を促進してホルモン依存性がんの病態進行に関わる
    (第46回日本分子生物学会年会 2023)
  • A potential tumor-promoting role of glycosyltransferase POMGnT1 in high-grade serous ovarian cancer
    (THE 82nd ANNUAL MEETING OF THE JAPANESE CANCER ASSOCIATION 2023)
  • Targeting FXYD3 positive cancer stem cells in radio-resistance
    (THE 82ND ANNUAL MEETING OF THE JAPANESE CANCER ASSOCIATION 2023)
  • A new RNAi nanotherapy for ovarian cancer stemness targeting a disease-specific long noncoding RNA OIN1
    (THE 82ND ANNUAL MEETING OF THE JAPANESE CANCER ASSOCIATION 2023)
more...
Professional career (1):
  • M.D., Ph.D. (University of Tokyo)
Committee career (4):
  • 2023/01 - 現在 日本癌学会 評議員
  • 2015/04 - 現在 日本内分泌学会 評議員
  • 2013/06 - 現在 日本抗加齢医学会 評議員
  • 2015/12 - 2017/11 日本学術振興会 科学研究費委員会専門委員(審査委員)
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