Ihara Yoshito

イハラヨシト | Ihara Yoshito

Affiliation and department：
Job title： Professor

Research field (4)： Pathobiochemistry , Medical biochemistry , Functional biochemistry , Structural biochemistry

Research keywords (6)：ストレス応答 , 糖鎖生物学 , 分子シャペロン , Stress response , Glycobiology , Molecular chaperone

Research theme for competitive and other funds (30)：

2022 - 2025 p53アミロイドーシスとしてのp53遺伝子変異卵巣癌の病態メカニズムの解明
2021 - 2024 Investigation of the pathophysiological functions of C-mannosyl tryptophan in ovarian cancer
2021 - 2024 胎盤形成不全における小胞体シャペロンーカルネキシンの発現と病態意義の解明
2019 - 2023 小胞体ストレスによる分子シャペロンの局在変化が胎盤形成不全に与える影響
2016 - 2021 Chemical Biology of ER related glycan modifications

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Papers (98)：

Yoshiko Takeda-Uchimura, Midori Ikezaki, Tomoya O Akama, Yoshito Ihara, Fabrice Allain, Kazuchika Nishitsuji, Kenji Uchimura. GlcNAc6ST2/CHST4 Is Essential for the Synthesis of R-10G-Reactive Keratan Sulfate/Sulfated N-Acetyllactosamine Oligosaccharides in Mouse Pleural Mesothelium. Molecules (Basel, Switzerland). 2024. 29. 4
Kazuchika Nishitsuji, Midori Ikezaki, Shino Manabe, Yoshito Ihara. Functions of Protein C-Mannosylation in Physiology and Pathology. Trends in Glycoscience and Glycotechnology. 2023. 35. 204. E23-E27
Kazuchika Nishitsuji, Midori Ikezaki, Shino Manabe, Yoshito Ihara. Functions of Protein C-Mannosylation in Physiology and Pathology. Trends in Glycoscience and Glycotechnology. 2023. 35. 204. E23-E27
Kazuchika Nishitsuji, Midori Ikezaki, Shino Manabe, Yoshito Ihara. Functions of Protein C-Mannosylation in Physiology and Pathology. Trends in Glycoscience and Glycotechnology. 2023. 35. 204. J23-J27
Naoyuki Iwahashi, Midori Ikezaki, Yoshihiro Komohara, Yukio Fujiwara, Tomoko Noguchi, Kaho Nishioka, Kazuko Sakai, Kazuto Nishio, Mitsuharu Ueda, Yoshito Ihara, et al. Cytoplasmic p53 aggregates accumulated in p53-mutated cancer correlate with poor prognosis. PNAS Nexus. 2022. 1. 3

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MISC (67)：

井原義人, 井内陽子, 岩橋尚幸, 南方志帆, 南方志帆, 森乃絢, 池崎みどり, 西辻和親, 井箟一彦, 眞鍋史乃. Pathophysiological response of protein C-mannosylation in ovarian cancer. 日本糖質学会年会要旨集. 2023. 42nd
西辻和親, 池崎みどり, 眞鍋史乃, 眞鍋史乃, 井原義人. Functions of Protein C-Mannosylation in Physiology and Pathology. Trends in Glycoscience and Glycotechnology (Web). 2023. 35. 204
西辻和親, 池崎みどり, 内村健治, 内村健治, 岩橋尚幸, 西岡香穂, 藤原章雄, 菰原義弘, 井箟一彦, 井原義人. Sulfated glycosaminoglycan-mediated spreading of p53 amyloid and its contribution to cancer pathology. 日本糖質学会年会要旨集. 2022. 41st
南方志帆, 井内陽子, 西辻和親, 眞鍋史乃, 眞鍋史乃, 井原義人. Investigating the cellular uptake mechanism of C-mannosyl tryptophan. 日本糖質学会年会要旨集. 2022. 41st
池崎みどり, 西辻和親, 眞鍋史乃, 眞鍋史乃, 内村健治, 内村健治, 伊藤幸成, 伊藤幸成, 井原義人. C-Mannosylated peptide attenuates astrocyte-induced synaptogenesis in rat cortical neurons. 日本糖質学会年会要旨集. 2022. 41st

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Education (4)：

- 1994 Osaka University
- 1994 Osaka University Graduate School, Division of Medicine
- 1990 The University of Tokushima Faculty of Medicine School of Medicine
- 1990 The University of Tokushima Faculty of Medicine School of Medicine

Professional career (1)：

Ph.D. (Osaka University)

Work history (10)：

2002 - 2007 Nagasaki University School of Medicine
2002 - 2007 Nagasaki University School of Medicine, Associate professor
2007 - - 和歌山県立医科大学医学部教授
2007 - - Wakayama Medical University, Professor
1998 - 2002 Nagasaki University School of Medicine

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Committee career (2)：

日本糖質学会評議員
日本生化学会評議員

Awards (2)：

1993 - 日本生化学会JB論文賞(第1回)
1993 - JB Award (The Japanese Biochemical Society)

Association Membership(s) (8)：

日本糖質学会 , 米国細胞生物学会(The American society for cell biology) , 日本癌学会 , 日本生化学会 , The Japanese Society of Carbohydrate Research , The American Society for Cell Biology , The Japanese Cancer Association , The Japanese Biochemical Society

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