Rchr
J-GLOBAL ID：200901020986488412   Update date: Feb. 08, 2024

Hirose Tetsuro

ヒロセ テツロウ | Hirose Tetsuro
Affiliation and department：
大阪大学 生命機能研究科・細胞ネットワーク講座・RNA生体機能研究室

About 大阪大学 生命機能研究科・細胞ネットワーク講座・RNA生体機能研究室


Job title： 教授
Homepage URL  (1)： http://www.fbs.osaka-u.ac.jp/labs/hirose/
Research field  (2)： Cell biology ,  Molecular biology
Research keywords  (8)： ノンコーディングRNA ,  RNA顆粒 ,  核内構造体 ,  エピジェネティックス ,  RNA結合タンパク質 ,  RNAスプライシング ,  ストレス応答 ,  相分離
Research theme for competitive and other funds  (36)：
  • 2021 - 2026 Functional analysis of nondomain-type lncRNAs
  • 2021 - 2026 Management of non-domain biopolymer research group
  • 2020 - 2023 Decoding the code for the lncRNA function to induce intracellular phase separation
  • 2020 - 2022 Inheritance mechanism of phase separated nuclear bodies built on noncoding RNAs
  • 2019 - 2021 Molecular mechanism to induce intracellular phase separation by RNA tangling
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Papers (125)：
  • Chikashi Obuse, Tetsuro Hirose. Functional domains of nuclear long noncoding RNAs: Insights into gene regulation and intracellular architecture. Current Opinion in Cell Biology. 2023
  • Tetsuya Yamamoto, Tomohiro Yamazaki, Kensuke Ninomiya, Tetsuro Hirose. Nascent ribosomal RNA act as surfactant that suppresses growth of fibrillar centers in nucleolus. Communications biology. 2023. 6. 1. 1129-1129
  • Hiro Takakuwa, Tomohiro Yamazaki, Sylvie Souquere, Shungo Adachi, Hyura Yoshino, Naoko Fujiwara, Tetsuya Yamamoto, Tohru Natsume, Shinichi Nakagawa, Gerard Pierron, et al. Shell protein composition specified by the lncRNA NEAT1 domains dictates the formation of paraspeckles as distinct membraneless organelles. Nature Cell Biology. 2023. 25. 11. 1664-1675
  • Kensuke Ninomiya, Tomohiro Yamazaki, Tetsuro Hirose. Satellite RNAs: emerging players in subnuclear architecture and gene regulation. The EMBO Journal. 2023. e114331
  • Chao Zeng, Takeshi Chujo, Tetsuro Hirose, Michiaki Hamada. Landscape of semi-extractable RNAs across five human cell lines. Nucleic Acids Research. 2023
ｍore...
MISC (47)：
  • 二宮賢介, 足達俊吾, 廣瀬哲郎, 廣瀬哲郎. The multifunctionality of HSATIII lncRNAs and its control mechanisms. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
  • 上野剛志, 足達俊吾, 二宮賢介, 廣瀬哲郎, 廣瀬哲郎, 廣瀬哲郎. Identification and analysis of regulatory proteins responsible for temperature-dependent recruitment of CLK1 to nuclear stress bodies. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
  • 廣瀬哲郎, 山崎智弘, 山本哲也. RNAs acting as scaffolds of intracellular structures. 実験医学. 2022. 40. 12
  • 高桑央, 山崎智弘, SOUQUERE Sylvie, PIERRON Gerard, 村上正晃, 廣瀬哲郎, 廣瀬哲郎. Molecular grammar of the SFPQ prion-like domain for the paraspeckle segregation from nuclear speckles. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
  • 山本哲也, 山崎智弘, 二宮賢介, 廣瀬哲郎. Nuclear body research by fusion of RNA molecular biology and soft matter physics. 月刊細胞. 2021. 53. 14
ｍore...
Lectures and oral presentations  (4)：
  • Regulatory Mechanisms of Intracellular Organization and Gene Expression by Noncoding RNAs
    (2022)
  • 非コードRNAによる細胞内構造構築
    (東京大学大学院新領域創成科学研究科セミナー 2022)
  • Construction mechanism of nuclear paraspeckle as an isolated RNP micell
    (EMBO | EMBL Symposia: Cellular Mechanisms Driven by Liquid Phase Separation 2022)
  • Regulatory mechanisms of Intracellular Organization by noncoding RNAs
Professional career (1)：
  • 理学博士 (名古屋大学)
Work history (8)：
  • 2020/04 - 現在 Osaka University Graduate School of Frontier Biosciences Professor
  • 2013/09 - 2020/10 Hokkaido University Institute for Genetic Medicine
  • 2013/04 - 2013/08 産業技術総合研究所 バイオメディカル研究部門 研究グループ長
  • 2005/09 - 2013/03 産業技術総合研究所 生物情報解析研究センター/バイオメディシナル情報研究センター 研究チーム長
  • 2004/04 - 2005/09 科学技術振興機構 さきがけ専任研究員
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Association Membership(s) (4)：
The RNA Society ,  JAPAN SOCIETY FOR CELL BIOLOGY ,  THE RNA SOCIETY OF JAPAN ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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