Rchr
J-GLOBAL ID：200901021227594468   Update date: Apr. 11, 2024

Shioda Norifumi

シオダ ノリフミ | Shioda Norifumi
Affiliation and department：
Kumamoto University Institute of Molecular Embryology and Genetics

About Kumamoto University Institute of Molecular Embryology and Genetics


Homepage URL  (1)： http://www.imeg.kumamoto-u.ac.jp/bunya_top/genomic_neurology/
Research field  (3)： Cell biology ,  Neuroscience - general ,  Pharmacology
Research keywords  (6)： Brain functions ,  G-quadruplex ,  Non-B form DNA and RNA structure ,  neurodevelopmental disorder ,  neurodegenerative disease ,  Repeat expansion diseases
Research theme for competitive and other funds  (23)：
  • 2023 - 2027 G4RNA相分離による神経機能制御メカニズムの解明
  • 2021 - 2025 Drug discovery for fragile X syndrome based on the small molecular ligands that form self-assembles on the CGG repeats
  • 2022 - 2024 グアニン四重鎖によるレトロトランスポゾン転移制御メカニズムの解明
  • 2021 - 2024 グアニン四重鎖によるプリオノイド・イノベーション
  • 2021 - 2023 脳機能におけるグアニン四重鎖DNA可塑性/弾性のマルチスケール解析
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Papers (117)：
  • Kenta Kudo, Karin Hori, Sefan Asamitsu, Kohei Maeda, Yukari Aida, Mei Hokimoto, Kazuya Matsuo, Yasushi Yabuki, Norifumi Shioda. Structural polymorphism of the nucleic acids in pentanucleotide repeats associated with the neurological disorder CANVAS. Journal of Biological Chemistry. 2024. 300. 4. 107138-107138
  • Susumu Ikenoshita, Kazuya Matsuo, Yasushi Yabuki, Kosuke Kawakubo, Sefan Asamitsu, Karin Hori, Shingo Usuki, Yuki Hirose, Toshikazu Bando, Kimi Araki, et al. A cyclic pyrrole-imidazole polyamide reduces pathogenic RNA in CAG/CTG triplet repeat neurological disease models. The Journal of clinical investigation. 2023
  • Kazuya Matsuo, Sefan Asamitsu, Kohei Maeda, Kosuke Kawakubo, Ginji Komiya, Kenta Kudo, Yusuke Sakai, Karin Hori, Susumu Ikenoshita, Shingo Usuki, et al. RNA G-quadruplexes forming scaffolds for alpha-synuclein aggregation lead to progressive neurodegeneration. 2023
  • Sefan Asamitsu, Yasushi Yabuki, Kazuya Matsuo, Moe Kawasaki, Yuki Hirose, Gengo Kashiwazaki, Anandhakumar Chandran, Toshikazu Bando, Dan Ohtan Wang, Hiroshi Sugiyama, et al. RNA G-quadruplex organizes stress granule assembly through DNAPTP6 in neurons. Science advances. 2023. 9. 8. eade2035
  • Qingyun Guo, Ichiro Kawahata, Wenbin Jia, Haoyang Wang, An Cheng, Yasushi Yabuki, Norifumi Shioda, Kohji Fukunaga. α-Synuclein decoy peptide protects mice against α-synuclein-induced memory loss. CNS neuroscience & therapeutics. 2023. 29. 6. 1547-1560
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MISC (64)：
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Professional career (1)：
  • 博士(薬学) (東北大学)
Work history (6)：
  • 2022/08 - 現在 Kumamoto University Institute of Molecular Embryology and Genetics Professor
  • 2018/07 - 2022/07 Kumamoto University Institute of Molecular Embryology and Genetics. Associate Professor (PI)
  • 2016/04 - 2018/06 Gifu Pharmaceutical University Associate Professor
  • 2014/10 - 2016/03 Tohoku University Graduate School of Pharmaceutical Sciences Adjunct Associate Professor
  • 2010/10 - 2014/09 Tohoku University Graduate School of Pharmaceutical Sciences Assistant Professor
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Committee career (2)：
  • - 現在 日本薬理学会評議員
  • - 現在 日本生化学会評議員
Awards (5)：
  • 2019/11 - 日本人類遺伝学会奨励賞
  • 2019/07 - 柿内三郎記念奨励研究賞
  • 2017/03 - 日本薬理学会奨励賞
  • 2015/05 - 日本生化学会東北支部奨励賞
  • 2014/09 - 日本神経化学会奨励賞
Association Membership(s) (11)：
THE JAPAN SOCIETY OF HUMAN GENETICS ,  JAPANESE SOCIETY FOR CHEMICAL BIOLOGY ,  日本神経科学会 ,  THE JAPANESE SOCIETY FOR NEUROCHEMISTRY ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  THE JAPANESE PHARMACOLOGICAL SOCIETY ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  日本核酸医薬学会 ,  日本分子生物学会 ,  日本RNA学会 ,  日本エピジェネティクス研究会
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