Rchr
J-GLOBAL ID：200901021344500822   Update date: Apr. 17, 2024

Takeshima Hiroshi

タケシマ ヒロシ | Takeshima Hiroshi
Affiliation and department：
Kyoto University

About Kyoto University


Research field  (1)： Medical biochemistry
Research keywords  (3)： Ca2+シグナル 興奮性細胞 ,  excitable cells ,  Ca2+ signal
Research theme for competitive and other funds  (42)：
  • 2022 - 2026 活動量の変化に伴う骨格筋の可塑的変化のメカニズムの解明
  • 2021 - 2024 TRIC and MG23 channels in store Ca2+ handling
  • 2020 - 2023 The genetic analysis and underlying function of the endoplasmic reticulum membrane protein targeting inherited arrhythmogenic syndromes
  • 2020 - 2023 心調律における細胞内小胞体カウンターイオンチャネル(TRIC)の重要性
  • 2018 - 2021 Study on TRIC and MG23 channels
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Papers (217)：
  • Atsuhiko Ichimura, Yuu Miyazaki, Hiroki Nagatomo, Takaaki Kawabe, Nobuhisa Nakajima, Ga Eun Kim, Masato Tomizawa, Naoki Okamoto, Shinji Komazaki, Sho Kakizawa, et al. Atypical cell death and insufficient matrix organization in long-bone growth plates from Tric-b-knockout mice. Cell Death & Disease. 2023. 14. 12
  • Yuu Miyazaki, Atsuhiko Ichimura, Ryo Kitayama, Naoki Okamoto, Tomoki Yasue, Feng Liu, Takaaki Kawabe, Hiroki Nagatomo, Yohei Ueda, Ichiro Yamauchi, et al. C-type natriuretic peptide facilitates autonomic Ca2+ entry in growth plate chondrocytes for stimulating bone growth. eLife. 2022. 11
  • 岡本 直樹, 市村 敦彦, 宮崎 侑, 北山 諒, 安江 智己, 劉 楓, 川邊 隆彰, 長友 宏樹, 柿澤 昌, 西 美幸, et al. C型ナトリウム利尿ペプチドは軟骨細胞内Ca2+シグナル経路を活性化し骨伸長を促進する. 日本薬学会年会要旨集. 2022. 142年会. 28M-pm16S
  • Feng Liu, Luxin Xu, Miyuki Nishi, Atsuhiko Ichimura, Hiroshi Takeshima. Enhanced Ca2+ handling in thioglycolate-elicited peritoneal macrophages. Cell Calcium. 2021. 96. 102381-102381
  • 宮崎 侑, 市村 敦彦, 北山 諒, 辻本 真人, 山崎 大樹, 西 美幸, 竹島 浩. カウンターイオンチャネルTRIC-Bの欠損はマウス成長板軟骨細胞において形態異常を引き起こす. 日本薬学会年会要旨集. 2020. 140年会. 28M-am06S
ｍore...
MISC (64)：
  • Kristyn Gumpper, Ki Ho Park, Mingzhai Sun, Pei-Hui Lin, Tao Tan, Miyuki Nishi, Hiroshi Takeshima, Jianjie Ma. TRIM Family Proteins in Intracellular Vesicle Trafficking. BIOPHYSICAL JOURNAL. 2017. 112. 3. 239A-239A
  • Xinyu Zhou, Kristyn Gumpper, Xinxin Wang, Junwei Wu, Tao Tan, Miyuki Nishi, Hiroshi Takeshima, Jianjie Ma, Hua Zhu. MG29 Interacts with Bin1 for Maintaining T-Tubule Structure in Skeletal Muscle Physiology and Regeneration. BIOPHYSICAL JOURNAL. 2017. 112. 3. 118A-118A
  • 武井大祐, 西美幸, 深田宗一朗, 土居雅夫, 岡村均, 上住聡芳, 吉田守克, 宮里幹也, 市村敦彦, 市村敦彦, et al. 活性化した筋衛星細胞におけるMyoD依存的なGm7325遺伝子の発現. 日本筋学会学術集会プログラム・抄録集. 2017. 3rd. 117-117
  • 趙 成珠, 市村 敦彦, 山本 浩司, 竹島 浩. TRIC-Bチャネルの骨形成と骨芽細胞における生理機能の解析. 日本薬学会年会要旨集. 2016. 136年会. 3. 179-179
  • Peihui Lin, Chuanxi Cai, Hua Zhu, Jae-Kyun Ko, Moonsun Hwang, Zui Pan, Tao Tan, Daiju Yamazaki, Hiroshi Takeshima, Irina Korichneva, et al. Zinc Binding to MG53 Facilitates Repair of Injury to Cell Membrane. BIOPHYSICAL JOURNAL. 2016. 110. 3. 589A-589A
ｍore...
Books (1)：
  • 基礎生命科学
    京都廣川書店 2008
Lectures and oral presentations  (4)：
  • TRIC channel subtypes, willing partners with Ca2+ release channels in intracellular stores
    (Gordon Research Conference: Ca2+ signaling 2011)
  • Immuno-proteomic approach to E-C coupling: junctophilin and TRIC channel in cardiac Ca2+ release
    (IUPS Whole-day Symposium 2009)
  • TRIC channel subtypes and SR/ER Ca2+ release
    (Gordon Research Conference: Muscle Excitation-Contraction Coupling 2009)
  • Molecular components supporting ryanodine receptor-mediated Ca2+ release: roles of junctophilin and TRIC channel in cardiac Ca2+ release
    (JST Japan-Mexico Scientific Workshop 2009)
Works (4)：
  • ノシセプチン受容体の生理機能
    1998 -
  • Physiological functions of nociceptin receptor
    1998 -
  • リアノジン受容体の構造と機能
    1994 -
  • Structure-function relationship of ryanodine receptor
    1994 -
Education (4)：
  • - 1989 Kyoto University
  • - 1989 Kyoto University Graduate School, Division of Medical Sciences
  • - 1983 Tokyo University of Agriculture and Technology Faculty of Agriculture
  • - 1983 Tokyo University of Agriculture and Technology Faculty of Agriculture
Professional career (1)：
  • 博士(医学) (京都大学)
Work history (12)：
  • 2000 - 2001 Kurume University Institute of Life Science
  • 2000 - 2001 Kurume University, Institute of Life Science, Professor
  • 2001 - - 東北大学 医学部 教授
  • 2001 - - Tohoku University, Faculty of medicine, Professor
  • 1995 - 2000 The University of Tokyo Faculty of Medicine
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Awards (1)：
  • 2000 - 生化学会奨励賞
Association Membership(s) (4)：
日本筋学会 ,  日本薬学会 ,  Biophysical Society ,  日本生化学会
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