Research theme for competitive and other funds (23)：
2022 - 2025 Enzymological studies on N-acyl-PS a novel triacyl-type phospholipid
2019 - 2022 The analysis of physiological functions of triacyl-type phospholipids
2016 - 2019 Enzymological analysis of a trace phosphopilid N-acyl-phosphatidylethanolamine
2015 - 2018 Biochemical and functional analysis of PLAAT family members as lipid-metabolizing enzymes
2014 - 2017 Novel mechanisms for the biosynthesis of the lipid mediator regulating appetite and obesity
2013 - 2016 Analyses of the generation mechanisms for the bioactive lipids N-acylethanolamines
2012 - 2015 Functional analysis of PLA/AT family members functioning as lipid-metabolizing enzymes
2009 - 2011 Enzymological analysis of N-acylethanolamines as lipid mediators
2007 - 2008 Analysis on the metabolism and physiological function of anandamide and related fatty acid amide compounds
2005 - 2006 Functional analysis of a novel enzyme of the phospholipase D type involved in the endocannabinoid
1999 - 2000 Enzymological and molecular biological studies on anandamide amidohydrolase
1997 - 1998 Studies on an enzyme hydrolyzing anandamide, an endogenous ligand for cannabinoid receptors
1997 - 1997 Biosynthesis and metabolism of cannabimimetic anandamide
1996 - 1996 内因性マリファナ様物質アナンダミドの代謝酵素の研究
1996 - 1996 中枢性カンナビノイド受容体の内因性リガンド(アナンダミド)の代謝
1995 - 1995 内因性マリファナ様物質のアナンダミドの代謝酵素に関する研究
1995 - 1995 Molecular pathophysiological studies on arachidonate lipoxygenases
1994 - 1995 Isozymes of cyclooxygenase and lipoxygenase
1994 - 1994 エイコサノイドによる脳下垂体前葉ホルモンの分泌調節に関する研究
1989 - 1991 Study on the physiological and pathological dynamics of cyclooxygenase and lipoxygenase enzymes
1987 - 1988 Studies on Mammalian Lipoxygenases
生理活性脂質代謝関連酵素に関する酵素学的ならびに分子生物学的研究
Enzymological and molecular biological studies on the enzymes involved in the metabolism of bioactive lipids
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Papers (155)：
Mohammad Mamun Sikder, Toru Uyama, Sumire Sasaki, Katsuhisa Kawai, Nobukazu Araki, Natsuo Ueda. PLAAT1 expression triggers fragmentation of mitochondria in an enzyme activity-dependent manner. Journal of biochemistry. 2023. 175. 1. 101-113
S M Khaledur Rahman, Sumire Sasaki, Toru Uyama, Zahir Hussain, Mohammad Mamun Sikder, Hiroyuki Saiga, Mari Ohmura-Hoshino, Ken-Ichi Ohta, Yoshimi Miki, Katsuaki Hoshino, et al. PLAAT1 deficiency alleviates high-fat diet-induced hepatic lipid accumulation in mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2023. 37. 7. e23032
Keisuke Kitakaze, Hanif Ali, Raiki Kimoto, Yasuhiro Takenouchi, Hironobu Ishimaru, Atsushi Yamashita, Natsuo Ueda, Tamotsu Tanaka, Yasuo Okamoto, Kazuhito Tsuboi. GDE7 produces cyclic phosphatidic acid in the ER lumen functioning as a lysophospholipid mediator. Communications biology. 2023. 6. 1. 524-524
Mauro Maccarrone, Vincenzo Di Marzo, Juerg Gertsch, Uwe Grether, Allyn C Howlett, Tian Hua, Alexandros Makriyannis, Daniele Piomelli, Natsuo Ueda, Mario van der Stelt. Goods and bads of endocannabinoid system as a therapeutic target: Lessons learned after 30 years. Pharmacological reviews. 2023
Margaryta Tevosian, Hristo Todorov, Ermelinda Lomazzo, Laura Bindila, Natsuo Ueda, Davide Bassetti, Davide Warm, Sergei Kirischuk, Heiko J Luhmann, Susanne Gerber, et al. NAPE-PLD deletion in stress-TRAPed neurons results in an anxiogenic phenotype. Translational psychiatry. 2023. 13. 1. 152-152
Keisuke Kitakaze, Hanif Ali, Raiki Kimoto, Yasuhiro Takenouchi, Hironobu Ishimaru, Atsushi Yamashita, Natsuo Ueda, Tamotsu Tanaka, Yasuo Okamoto, Kazuhito Tsuboi. Cyclic phosphatidic acid is produced by GDE7 in the ER lumen as a lysophospholipid mediator. Research Square. 2022
1983 - 1987 The University of Tokushima, Graduate School Division of Medicine (PhD course)
1977 - 1983 The University of Tokushima Faculty of Medicine School of Medicine
Professional career (1)：
医学博士 (The University of Tokushima)
Work history (5)：
2003/10 - 現在 香川大学医学部, 教授
2001 - 2003 Kagawa Medical University
1994 - 2000 The University of Tokushima Faculty of Medicine
1988 - 1994 The University of Tokushima Faculty of Medicine
1987 - 1988 The University of Tokushima Faculty of Medicine
Committee career (6)：
2021 - 現在 日本ビタミン学会 理事
2003 - 現在 日本脂質生化学会 幹事
1996 - 現在 日本炎症・再生医学会 評議員
2009/05 - 2021 日本ビタミン学会 幹事
1998/05 - 2009/05 日本ビタミン学会 評議員
日本生化学会 評議員
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Awards (3)：
2020 - International Cannabinoid Research Society Mechoulam Award Enzymological studies on endocannabinoids and related N-acylethanolamines
2018 - 日本ビタミン学会 学会賞
1990 - 日本ビタミン学会 奨励賞
Association Membership(s) (7)：
国際カンナビノイド研究会 (International Cannabinoid Research Society)
, 日本脂質生化学会
, 米国生化学分子生物学会(American Society for Biochemistry and Molecular Biology)
, 日本炎症・再生医学会
, 日本ビタミン学会
, 日本生化学会
, 日本栄養・食糧学会
