Rchr
J-GLOBAL ID：200901022100319529   Update date: Jan. 30, 2024

Terada Tomoyuki

テラダ トモユキ | Terada Tomoyuki
Affiliation and department：
Osaka Ohtani University Faculty of Phamacy

About Osaka Ohtani University Faculty of Phamacy


Job title： Professor Emeritus
Homepage URL  (2)： http://www.osaka-ohtani.ac.jp/dept/ph/index.html ,  http://www.osaka-ohtani.ac.jp/
Research field  (4)： Functional biochemistry ,  Clinical pharmacy ,  Pharmacology ,  Pharmaceuticals - health and biochemistry
Research keywords  (7)： transcriptional factor ,  enzyme expression ,  cDNA cloning ,  enzyme gene ,  enzymology ,  Drug and Xenobiotic Metabolism ,  Cellular and Molecular Biology
Research theme for competitive and other funds  (9)：
  • 1997 - 1998 トレフォイルペプチドの機能構造と細胞増殖制御に果す役割
  • 1996 - 1997 Relationship between wild type and point-mutated bovine liver dihydrodiol dehydrogenase 3, DD3 in their 3D-structures and activities
  • 1995 - 1996 Cellular Biochemical Studies on Reulatory Mechanism of Gastric Acid Secretion
  • The anlytical studies for the protein function
  • Research for the detection and analyses of cancer progeressions
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Papers (89)：
  • Kahori Shimizu, Moe Ono, Takenari Mikamoto, Yuya Urayama, Sena Yoshida, Tomomi Hase, Shotaro Michinaga, Hiroki Nakanishi, Miho Iwasaki, Tomoyuki Terada, et al. Overexpression of lysophospholipid acyltransferase, LPLAT10/LPCAT4/LPEAT2, in the mouse liver increases glucose-stimulated insulin secretion. The FASEB Journal. 2024. 38. 2
  • Kahori Shimizu, Syogo Nishimuta, Yuri Fukumura, Shotaro Michinaga, Yuka Egusa, Tomomi Hase, Tomoyuki Terada, Fuminori Sakurai, Hiroyuki Mizuguchi, Koji Tomita, et al. Liver-specific overexpression of lipoprotein lipase improves glucose metabolism in high-fat diet-fed mice. PLOS ONE. 2022. 17. 9. e0274297-e0274297
  • Shimizu, K, Egusa, Y, Nishimuta, S, Fukumura, Y, Yoshimura, M, Inomoto, T, Terada, T, Tomita, K, Nishinaka, T. Dietary calamondin supplementation slows the progression of non-alcoholic fatty liver disease in C57BL/6 mice fed a high-fat diet. Int.J.Food Sci.Nutr. 2021. 72. 3. 335-347
  • Shimizu, K, Ogiya, Y, Yoshinaga, K, Kimura, H, Michinaga, S, Ono, M, Taketomi, A, Terada, T, Sakurai, F, Mizuguchi, H, et al. ZFAND3 Overexpression in the Mouse Liver Improves Glucose Tolerance and Hepatic Insulin Resistance. Exp.Clin.Endocrinol.Diabetes. 2021
  • Shimizu, K, Sakurai, F, Iizuka, S, Ono, R, Tsukamoto, T, Nishimae, F, Nakamura, S. I, Nishinaka, T, Terada, T, Fujio, Y, et al. Adenovirus Vector-Induced IL-6 Promotes Leaky Adenoviral Gene Expression, Leading to Acute Hepatotoxicity. J.immunol. 2021. 206. 2. 410-421
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MISC (11)：
  • 清水かほり, 西中徹, 冨田晃司, 寺田知行. 糖尿病治療・予防を目指した改良型アデノウイルスベクターによる遺伝子と食品に関する検討The investigation of genes using an improved adenovirus vector and food for the treatment and prevention of type 2 diabetes mellitus. 薬学雑誌. 2018. 139. 47-51
  • Kahori Shimizu, Sakurai Fuminori, Shunsuke Iizuka, Masashi Tachibana, Toru Nishinaka, Tomoyuki Terada, Hiroyuki Mizuguchi. Adenovirus Vector-Induced Hepatotoxicity During the Early Phase of Adenoviral Treatment Is Attributed to Inflammatory Cytokine-Induced Leaky Expression of Adenovirus Genes. MOLECULAR THERAPY. 2017. 25. 5. 264-265
  • K. Shimizu, Y. Ogiya, T. Nishinaka, F. Sakurai, H. Mizuguchi, K. Tomita, T. Terada. Study of zinc finger AN1-type domain gene transduction by a novel adenovirus vector with lower hepatotoxicity for treatment of diabetes mellitus. HUMAN GENE THERAPY. 2016. 27. 11. A179-A179
  • Takeshi Miura, Toru Nishinaka, Tomoyuki Terada. Potential Targeting Region for the Specific Inhibition of Human Monomeric Carbonyl Reductases of the Short-Chain Dehydrogenase/Reductase Superfamily. DRUG METABOLISM REVIEWS. 2009. 41. 54-55
  • Takeshi Miura, Toru Nishinaka, Tomoyuki Terada. COMPARATIVE STUDY OF HUMAN MONOMERIC CARBONYL REDUCTASES IN TISSUE DISTRIBUTION, REDUCTASE ACTIVITY, AND COENZYME SPECIFICITY. DRUG METABOLISM REVIEWS. 2007. 39. 191-192
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Patents (3)：
  • Method of inhibiting aldose reductase in vivo with intrinsic inhibitors of aldose reductase.
  • Method of inhibiting aldose reductase in vivo with intrinsic inhibitors of aldose reductase.
  • Process for making intrinsic inhibitors of aldose reductase
Books (10)：
  • The Enzymes
    2019
  • The Enzymes
    2015
  • Regulation of promoter activity of the aldose reductase gene through the multiple stress response region, MSRR
    Enzymology and Molecular Biology of Carbonyl Metabolism 13, Purdue Press 2007
  • Expression of carbonyl reductases in fetal human brain, but not in adult
    Enzymology and Molecular Biology of Carbonyl Metabolism 13, Purdue Press 2007
  • Cloning and expression of cDNA encoding bovine liver dihydrodiol dehydrogenase 3, DD3.
    Adv.Exp.Med.Biol. 1997
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Lectures and oral presentations  (129)：
  • 高脂肪食摂取マウスに対してアジアの柑橘類か_与える影響の検討
    (第68回 日本薬学会近畿支部大会 2019)
  • 改良型アデノウイルスベクターを用いたホスファチジルエタノールアミンメチル基転移酵素の高発現がマウス初代培養肝細胞に与える影響の検討
    (第68回 日本薬学会近畿支部大会 2019)
  • リポタンパク質リパーゼの肝臓特異的な高発現か_高脂肪食摂取マウスに与える影響の検討
    (第68回 日本薬学会近畿支部大会 2019)
  • 2型糖尿病感受性遺伝子の高発現および発現抑制がエネルギー代謝に与える影響の検討 -カルシウムカルモジュリン依存性キナーゼ-
    (第68回 日本薬学会近畿支部大会 2019)
  • 2 型糖尿病感受性遺伝子の高発現が糖代謝に与える影響の検討 -AN1 型ジンクフィンガータンパク質-
    (第68回 日本薬学会近畿支部大会 2019)
ｍore...
Works (3)：
  • ヒトヒドロキシステロイド/ジヒドロジオール脱水素多型に関する研究
    1998 -
  • Study of a novel variant of human 3α-hydroxysteroid/dehydrodiol dehydrogenase.
    1998 -
  • Process for making intrinsic inhibitors of aldose reductase
    1991 -
Education (4)：
  • - 1980 Osaka University
  • - 1980 Osaka University Graduate School, Division of Pharmaceutical Sciences
  • - 1978 Osaka University of Pharmaceutical Sciences Faculty of Pharmaceutical Sciences
  • - 1978 Osaka University of Pharmaceutical Sciences Faculty of Pharmaceutical Science
Professional career (1)：
  • Ph.D.(Pharmaceutical Sciences) (Osaka University)
Work history (9)：
  • 2021/06 - 現在 Osaka Ohtani University Faculty of Phamacy Professor Emeritus
  • 2021/06 - 2021/06 Osaka Ohtani University Laboratory of Biochemistry, Faculty of Pharmacy, Professor Emeritus
  • 2006/04 - 2019/03 Faculty of Pharmacy, Osaka Ohtani University Professor
  • 2005/04 - 2006/03 Faculty of Education and Social Welfare, Ohtani Women's University Professor
  • 2005/01 - 2005/03 Graduate School of Pharmaceutical Sciences, Osaka University Associste Professor
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Committee career (13)：
  • 2019/04 - 現在 日本薬学会 代議員
  • 2006/04 - 現在 日本薬学会 近畿支部委員
  • 2013/04 - 2015/03 日本薬学会 代議員
  • 2012/04 - 2014/03 日本薬学会近畿支部会 幹事
  • 2010/04 - 2013/03 日本薬学会 Biol.Pharm.Bull. 誌 編集委員
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Association Membership(s) (10)：
International Work Shop of Carbonyl Metabolism ,  日本生化学会 ,  日本薬学会 ,  International Workshop of Enzymology and Molecular Biology of Carbonyl Metabolism ,  Japan Society of Endocrine Disruptor Research ,  Japanese Society of Toxicology ,  Japanese Society for the Study of Xenobiotics ,  Molecular Biology Society of Japan ,  Japanese Society of Biochemistry ,  Japanese Society of Pharmaceutical Sciences
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