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J-GLOBAL ID：200901022124152587   Update date: Apr. 25, 2024

Kimura Tohru

キムラ トオル | Kimura Tohru
Affiliation and department：
Kitasato University School of Science

About Kitasato University School of Science


Job title： Professor
Homepage URL  (1)： http://www.kitasato-u.ac.jp/sci/resea/seibutsu/stemcell/index.html
Research field  (2)： Zoological sciences ,  Developmental biology
Research keywords  (2)： 幹細胞学と生殖細胞学 ,  Stem cell and germ cell biology
Research theme for competitive and other funds  (23)：
  • 2023 - 2028 DNAメチル化編集技術を使った、エピゲノム制御コアの探索と解析
  • 2022 - 2025 雌雄の生殖細胞の性分化を推進させるクロマチンリモデリング複合体の解析
  • 2020 - 2023 がん幹細胞発生でのAktシグナル経路によるエピゲノム制御と代謝制御の解明
  • 2011 - 2015 Regulation of cellular function by late endosomal kinase signaling
  • 2012 - 2014 生殖細胞と多能性幹細胞の相互転換
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Papers (73)：
  • JunLong Chen, Shinichiro Horiuchi, So Kuramochi, Tomoyuki Kawasaki, Hayato Kawasumi, Saeko Akiyama, Tomoki Arai, Kenichi Morinaga, Tohru Kimura, Tohru Kiyono, et al. Human intestinal organoid-derived PDGFRα + mesenchymal stroma enables proliferation and maintenance of LGR4 + epithelial stem cells. Stem cell research & therapy. 2024. 15. 1. 16-16
  • Saeko Akiyama, Noriaki Saku, Shoko Miyata, Kenta Ite, Hidenori Nonaka, Masashi Toyoda, Akihide Kamiya, Tohru Kiyono, Tohru Kimura, Mureo Kasahara, et al. Drug metabolic activity as a selection factor for pluripotent stem cell-derived hepatic progenitor cells. Progress in molecular biology and translational science. 2023. 199. 155-178
  • Kenta Ite, Masashi Toyoda, Saeko Akiyama, Shin Enosawa, Saeko Yoshioka, Takaaki Yukitake, Mayu Yamazaki-Inoue, Kuniko Tatsumi, Hidenori Akutsu, Hiroshi Nishina, et al. Stem cell challenges and opportunities. Progress in molecular biology and translational science. 2023. 199. 379-395
  • Yoko Itakura, Yasuko Hasegawa, Yurika Kikkawa, Yuina Murakami, Kosuke Sugiura, Chiaki Nagai-Okatani, Norihiko Sasaki, Mariko Umemura, Yuji Takahashi, Tohru Kimura, et al. Spatiotemporal changes of tissue glycans depending on localization in cardiac aging. Regenerative therapy. 2023. 22. 68-78
  • Tohru Kimura, Batdorj E, AlOgayil N, Zhuang QK, Galvez JH, Bauermeister K, Nagata K, Kimura T, Ward MA, Taketo T, et al. Genetic variation in the Y chromosome and sex-biased DNA methylation in somatic cells in the mouse. Mammalian genome : official journal of the International Mammalian Genome Society. 2022
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MISC (15)：
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Patents (2)：
  • 分化状態の制御が可能な高等動物細胞を提供する方法
  • HIVコファクター抑制剤
Books (6)：
  • Regulatory Networks in Stem Cells
    Humana/Springer 2009
  • Developmental Biology of Neoplastic Growth, Progress in Molecular and Subcellular Biology Series
    Springer 2005
  • The Gene Knockout Factsbook II
    Academic Press 1998
  • Apoptosis, Pezcoller Foundation Symposia Publicatiuon
    Plenum Press 1994
  • The Status of Differentiation Therapy of Cancer vol. II, Serono Symposia Publication from
    Raven Press 1991
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Works (24)：
  • マウスPIWIファミリーによる減数分裂期の染色体構造の制御
    2012 -
  • 幹細胞システム制御機構におけるリン酸化シグナルの機能解析
    2011 -
  • マウスPIWIファミリーによる減数分裂期の染色体構造の制御
    2011 -
  • 幹細胞システム制御機構におけるリン酸化シグナルの機能解析
    2010 -
  • 幹細胞システム制御機構におけるリン酸化シグナルの機能解析
    2009 -
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Education (2)：
  • - 1994 Osaka University
  • - 1989 Osaka University School of Science
Professional career (1)：
  • PhD
Work history (7)：
  • 2013/04 - 現在 Kitasato University School of Science Professor
  • 2010/04 - 2013/03 Osaka University
  • 2005/02 - 2010/03 Osaka University
  • 2001/11 - 2005/01 Osaka University Research Institute for Microbial Diseases
  • 1998/09 - 2001/10 Osaka University Research Institute for Microbial Diseases Assistant Professor
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Awards (1)：
  • 1995 - 井上研究奨励賞
Association Membership(s) (4)：
International Society for Stem Cell Research ,  日本発生生物学会 ,  日本生化学会 ,  日本分子生物学会
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