Takara Kohji

タカラコウジ | Takara Kohji

Affiliation and department：
Job title： Associate Professor

Research field (3)： Clinical pharmacy , Pharmacology , Pharmaceuticals - health and biochemistry

Research keywords (3)：生物系薬学 , 医療薬学 , Biopharmaceutics

Research theme for competitive and other funds (9)：

2014 - 2017 Establishment of an novel reversal of anticancer drug resistance based on the epigenetic information
2008 - 2013 低酸素下における癌細胞の抗癌剤感受性に関する分子生物学的解析
2008 - 2013 抗癌剤感受性に及ぼす影響因子の網羅的解析
2011 - 2012 Individualization of cancer chemotherapyusing the epigenetic mutation analysis
2009 - 2010 Development and clinical application of biomarker for predicting the sensitivity to chemotherapeutic agents

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Papers (108)：

YUKO NAKAYAMA, DAICHI ENOMOTO, KAZUHIRO YAMAMOTO, KOHJI TAKARA. Molecular Characteristics of Everolimus-resistant Renal Cell Carcinoma Cells Generated by Continuous Exposure to Everolimus. Anticancer Research. 2023. 43. 10. 4349-4357
YUKO NAKAYAMA, KOHJI TAKARA, TETSUYA MINEGAKI, KAZUHIRO YAMAMOTO, TOMOHIRO OMURA, IKUKO YANO. Induction of Cross-resistance to ABCB1 Substrates in Venetoclax-resistant Human Leukemia HL60 Cells. Anticancer Research. 2021. 41. 9. 4239-4248
Komada F, Nakayama Y, Takara K. [Analysis of Time-to-onset and Onset-pattern of Interstitial Lung Disease after the Administration of Monoclonal Antibody Agents]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2018. 138. 12. 1587-1594
Fumiaki Kitazawa, Shin-ichi Fuchida, Yoko Kado, Kumi Ueda, Takatoshi Kokufu, Akira Okano, Mayumi Hatsuse, Satoshi Murakami, Yuko Nakayama, Kohji Takara, et al. Pharmacokinetic Interaction Between Tacrolimus and Fentanyl in Patients Receiving Allogeneic Hematopoietic Stem Cell Transplantation. ANNALS OF TRANSPLANTATION. 2017. 22. 575-580
Fumiaki Kitazawa, Shin-Ichi Fuchida, Fumitaka Ise, Yoko Kado, Kumi Ueda, Takatoshi Kokufu, Akira Okano, Mayumi Hatsuse, Satoshi Murakami, Yuko Nakayama, et al. Combination of lenalidomide and low-dose dexamethasone therapy promotes the anticoagulant activity of warfarin in patients with immunoglobulin light-chain amyloidosis. ONCOLOGY LETTERS. 2017. 14. 1. 475-479

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MISC (144)：

中山優子, 高良恒史, 山本和宏, 大村友博, 矢野育子. 消化管上皮細胞モデルにおけるABCB1発現・機能に及ぼすエベロリムス長期曝露の影響. 日本薬学会年会要旨集. 2021. 141年会. 29P01-289
牧野夢叶, 堀部紗世, 楠見里紗, 豊田真世子, 河内正二, 佐々木直人, 高良恒史, 力武良行. 活性酸素の増加はシスプラチン耐性獲得に関与する. 日本薬学会年会要旨集. 2020. 140年会. 28P-am035S
中山優子, 高良恒史, 峯垣哲也, 山本和宏, 矢野育子. 新規Bcl-2選択的阻害剤の長期間曝露がヒト白血病細胞株に及ぼす影響. 日本薬学会年会要旨集. 2019. 139年会. 4. 133-133
北澤文章, 片山実佳, 村山和子, 森本拓也, 上田久美, 中山優子, 高良恒史, 佐原敏之, 淵田真一, 島崎千尋. 同種造血幹細胞移植時に発現する口腔粘膜炎の重症度に影響を与えるリスク因子. 日本病院薬剤師会雑誌. 2018. 54. 9. 1126-1130
駒田富佐夫, 中山優子, 高良恒史. モノクローナル抗体医薬品による血液に対する有害事象の発症時期ならびに発症パターンに関する調査. 医薬品情報学. 2018. 20. 2. 72-80

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Books (1)：

Pathophysiological and Biochemical Analyses for “Life-Style Related or Intractable Diseases” - Target Validation for Drug Therapy
Research Signpost 2006

Education (3)：

1996 - 2000 Kobe University
1994 - 1996 Kyoto Pharmaceutical University Graduate School of Pharmaceutical Sciences
1990 - 1994 Kyoto Pharmaceutical University Pharmaceutical Sciences Pharmacy

Professional career (2)：

Work history (3)：

Committee career (1)：

Association Membership(s) (6)：

日本TDM学会 , 日本臨床薬理学会 , 日本薬物動態学会 , 日本医療薬学会 , 日本癌学会 , 日本薬学会

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