Hirashima Masanori

ヒラシママサノリ | Hirashima Masanori

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： https://www.med.niigata-u.ac.jp/pha/

Research field (2)： Pharmacology , Anatomy

Research keywords (5)： VEGF , embryonic edema , development , blood vessels , lymphatic vessels

Research theme for competitive and other funds (13)：

2022 - 2025 血小板とリンパ管内皮細胞の相互作用を標的にした新たなリンパ浮腫治療の開発
2022 - 2025 リンパ管・血管分離を維持する血小板放出因子の作用機序
2021 - 2024 リンパ節におけるリンパ洞フィルターの分子・細胞基盤と免疫応答制御
2020 - 2023 血小板のリンパ組織発生における役割:生理活性物質の運び手としての血小板
2017 - 2019 ヒト胎児疾患モデルマウスの新規スクリーニング法の確立

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Papers (49)：

Hiromi Matsuda, Yoshiya Ito, Kanako Hosono, Seri Tsuru, Tomoyoshi Inoue, Shuji Nakamoto, Chie Kurashige, Masanori Hirashima, Shuh Narumiya, Hirotsugu Okamoto, et al. Roles of Thromboxane Receptor Signaling in Enhancement of Lipopolysaccharide-Induced Lymphangiogenesis and Lymphatic Drainage Function in Diaphragm. Arteriosclerosis, thrombosis, and vascular biology. 2021. 41. 4. 1390-1407
Kenji Matsuzawa, Hayato Ohga, Kenta Shigetomi, Tomohiro Shiiya, Masanori Hirashima, Junichi Ikenouchi. MAGIs regulate aPKC to enable balanced distribution of intercellular tension for epithelial sheet homeostasis. Communications biology. 2021. 4. 1. 337-337
Hasegawa, Akito, Hayashi, Ryota, Shimomura, Yutaka, Hirashima, Masanori, Abe, Riichiro. Only plantar lesion of punctate palmoplantar keratoderma with a novel missense mutation in the AAGAB gene: Two Japanese familial case reports and review of reported mutations. The Journal of Dermatology. 2021. 48. 12. 1926-1930
Ikue Tai-Nagara, Yukiko Hasumi, Dai Kusumoto, Hisashi Hasumi, Keisuke Okabe, Tomofumi Ando, Fumio Matsuzaki, Fumiko Itoh, Hideyuki Saya, Chang Liu, et al. Blood and lymphatic systems are segregated by the FLCN tumor suppressor. Nature communications. 2020. 11. 1. 6314-6314
Ueta K, Otowa Y, Kakeji Y, Hirashima M. PROX1 Is Associated with Cancer Progression and Prognosis in Gastric Cancer. Anticancer Res. 2018. 38. 11. 6139-6145

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MISC (5)：

Masanori Hirashima. Regulation of endothelial cell differentiation and arterial specification by VEGF and Notch signaling. ANATOMICAL SCIENCE INTERNATIONAL. 2009. 84. 3. 95-101
M Hirashima, T Suda. Differentiation of arterial and venous endothelial cells and vascular morphogenesis. ENDOTHELIUM-JOURNAL OF ENDOTHELIAL CELL RESEARCH. 2006. 13. 2. 137-145
J Rossant, M Hirashima. Vascular development and patterning: making the right choices. CURRENT OPINION IN GENETICS & DEVELOPMENT. 2003. 13. 4. 408-412
Nishikawa SI, Hirashima M, Nishikawa S, Ogawa M. Cell biology of vascular endothelial cells. Ann N Y Acad Sci. 2001. 947. 35-40
H Yoshida, N Takakura, M Hirashima, H Kataoka, K Tsuchida, S Nishikawa, S Nishikawa. Hematopoietic tissues, as a playground of receptor tyrosine kinases of the PDGF-receptor family. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY. 1998. 22. 3. 321-332

Education (2)：

1995 - 1999 京都大学大学院医学研究科博士課程分子医学系専攻
1989 - 1995 Kyoto University Faculty of Medicine Department of Medical Science

Professional career (1)：

博士(医学) (京都大学)

Work history (5)：

2019/01 - 現在 Niigata University Graduate School of Medical and Dental Sciences
2007/09 - 2018/12 Kobe University Graduate School of Medicine
2004/03 - 2007/08 Keio University School of Medicine
1999/11 - 2004/02 サミュエル・ルネンフェルド研究所博士研究員
1999/04 - 1999/10 Kyoto University Graduate School of Medicine

Awards (2)：

2009/09 - 成人血管病研究振興財団岡本研究奨励賞(第24回) 内皮細胞分化と血管・リンパ管形成に関する研究
2006/12 - 第14回日本血管生物医学会学術集会 Best Young Investigator Award

Association Membership(s) (4)：

THE JAPANESE SOCIETY ON THROMBOSIS AND HEMOSTASIS , THE JAPANESE VASCULAR BIOLOGY AND MEDICINE ORGANIZATION , THE JAPANESE SOCIETY OF LYMPHOLOGY , THE JAPANESE PHARMACOLOGICAL SOCIETY

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