Research keywords (3)：
タンパク質の構造機能相関
, 高速原子間力顕微鏡
, 1分子計測
Research theme for competitive and other funds (15)：
2023 - 2027 The role of phase-separation upon radiation-induced DNA damages
2023 - 2026 Molecular mechanisms of the bacterial magnetic organelle surface proteins that functionalize the magnetosome as a biological magnetic needle
2022 - 高速原子間力顕微鏡を用いた子宮頸がん主要因タンパク質複合体の構造動態解明
2019 - 2021 ストレス依存的な細胞内外小胞の新規形態様式
2014 - 2019 Development of advanced high-speed AFM and analysis of proteins' action mechanism
2015 - 2018 New Paradigm for molecular mechanism of amyloid formation and disaggregation
2015 - 2017 Construction of a new reconstruction system and analysis of dynamic protein secretion machinery
2012 - 2017 Opening up New Structural Biology by High-speed AFM
2015 - 2016 ユビキチンによるタンパク質翻訳後修飾のダイナミクス
2013 - 2014 ユビキチンによるタンパク質翻訳後修飾のダイナミクス
2011 - 2013 葉緑体型ATP合成酵素の活性調節機構を構造の側面から理解する
2006 - 2010 ATP合成酵素の回転モーター制御の分子機構
2007 - 2009 εサブユニットによる葉緑体型ATP合成酵素の活性調節機構
2006 - 2007 葉緑体ATP合成酵素の活性調節機構の解明 研究課題
2000 - 2002 葉緑体内で回転するF1
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Papers (54)：
Kazusa Takeda, Holger Flechsig, Ikumi Muro, Romain Amyot, Fuminori Kobayashi, Noriyuki Kodera, Toshio Ando, Hiroki Konno. Structural Dynamics of E6AP E3 Ligase HECT Domain and Involvement of a Flexible Hinge Loop in the Ubiquitin Chain Synthesis Mechanism. Nano Letters. 2023. 23. 24. 11940-11948
Tomoko Hirano, Kazuo Ebine, Takashi Ueda, Takumi Higaki, Takahiro Watanabe-Nakayama, Hiroki Konno, Hisako Takigawa-Imamura, Masa H Sato. The SYP123-VAMP727 SNARE complex delivers secondary cell wall components for root hair shank hardening in Arabidopsis. The Plant cell. 2023. 35. 12. 4347-4365
Masaharu Hazawa, Dini Kurnia Ikliptikawati, Yuki Iwashima, De-Chen Lin, Yuan Jiang, Yujia Qiu, Kei Makiyama, Koki Matsumoto, Akiko Kobayashi, Goro Nishide, et al. Super-enhancer trapping by the nuclear pore via intrinsically disordered regions of proteins in squamous cell carcinoma cells. Cell Chemical Biology. 2023
小野賢二郎, 中山隆宏, 辻まゆみ, 梅田健一, 小口達敬, 紺野宏記, 篠原もえ子, 木内祐二, 古寺哲幸, TEPLOW David B. 高速原子間力顕微鏡を用いたAβプロトフィブリルの構造動態とレカネマブの作用. Dementia Japan. 2023. 37. 4
佐藤雅彦, 海老根一生, 上田貴志, 檜垣匠, 紺野宏記, 中山隆宏, 平野朋子. SYP123-VAMP727 is involved in the secretion of the inner cell wall components to the root hair shank in Arabidopsis. 日本植物生理学会年会(Web). 2022. 63rd
紺野宏記, 羽澤勝治, 芳坂綾子, 佐々木理乃, 矢幡信成, 古寺哲幸, 安藤敏夫. Investigation of formation process of Prx high molecular weight complexes and its physiological significance. 日本生体エネルギー研究会討論会講演要旨集. 2020. 46th
室郁弥, 中山(渡辺)隆宏, 古寺哲幸, 安藤敏夫, 紺野宏記. Observation of the structural dynamics of HECT-type ubiquitin ligase using high-speed AFM. 日本生体エネルギー研究会討論会講演要旨集. 2020. 46th
Structural biology of the mechanism of linear ubiquitin modification by the linear ubiquitin synthase LUBAC-ubiquitin binding enzyme (E2) complex
(2023)
1999 - 2002 Tokyo Institute of Technology Interdisciplinary Graduate School of Science and Engineering Department of Electronic Chemistry
1997 - 1999 Kanazawa University
1995 - 1997 Kanazawa University
1990 - 1994 Hokkaido Pharmaceutical University School of Pharmacy Department of Pharmacy Department of Pharmacy
Professional career (1)：
Doctor of Science (Tokyo Institute of Technology)
Work history (7)：
2017/10 - 現在 Kanazawa University
2011/11 - 2017/09 Kanazawa University
2009/08 - 2011/10 Tokyo Institute of Technology Chemical Resources Laboratory, Resources Recycling Process Laboratory, Chemical Resources Laboratory Resources Recycling Process Laboratory Assistant Professor
2005/08 - 2009/07 -:東京工業大学 資源化学研究所 助手
2002/04 - 2005/07 :科学技術振興機構 ERATO ATP システムプロジェクト 研究員
2000/01 - 2002/03 :日本学術振興会 特別研究員
1994/04 - 1995/03 岩手県立釜石病院 薬剤師
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Committee career (3)：
2020/03 - 2020/12 日本生体エネルギー研究会 第46回討論会 代表世話人
2014 - 2016 日本生化学会北陸支部 幹事
2015 - 2015 日本生物物理学会 第53回日本生物物理学会実行委員
Awards (1)：
2018/09 - Biophysics and Physicobiology Editors' Choice Award 2018 Demonstration of correlative atomic force and transmission electron microscopy using actin cytoskeleton
Association Membership(s) (3)：
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
, THE JAPANESE BIOCHEMICAL SOCIETY
, THE BIOPHYSICAL SOCIETY OF JAPAN
