Ogura Toshihiko

オグラトシヒコ | Ogura Toshihiko

Affiliation and department：
Job title： Professor

Research field (3)： Developmental biology , Molecular biology , Neuroscience - general

Research keywords (2)： mitochondria , 心臓、脈管発生

Research theme for competitive and other funds (45)：

2020 - 2024 Nuclear in situ metabolisms and nuclear receptors.
2019 - 2021 抗PD-1抗体不応答性がん患者に有効な併用治療薬の開発
2015 - 2021 細胞質から核に至る力覚機構の解明と新技術開発から医学的展開を目指す基礎研究
2018 - 2020 Molecular analyses on the common physiological aspects of astronauts and bed-ridden old patients.
2016 - 2019 Bio-platform to achieve mechanical stimulus to & resopose measurement of cell nucleus

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Papers (80)：

Atsushi Kubo, Keisuke Hitachi, Ryutaro Shirakawa, Toshihiko Ogura. Protective effects of Mkl1/2 against lipodystrophy and muscle atrophy via PI3K/AKT-independent FoxO repression. bioRxiv. 2023
Muna Al-Habsi, Kenji Chamoto, Ken Matsumoto, Norimichi Nomura, Baihao Zhang, Yuki Sugiura, Kazuhiro Sonomura, Aprilia Maharani, Yuka Nakajima, Yibo Wu, et al. Spermidine activates mitochondrial trifunctional protein and improves antitumor immunity in mice. Science. 2022. 378. 6618
Satoshi Furukawa, Masahiro Chatani, Atsushi Higashitani, Akira Higashibata, Fuminori Kawano, Takeshi Nikawa, Takuro Numaga-Tomita, Toshihiko Ogura, Fuminori Sato, Atsuko Sehara-Fujisawa, et al. Findings from recent studies by the Japan Aerospace Exploration Agency examining musculoskeletal atrophy in space and on Earth. NPJ microgravity. 2021. 7. 1. 18-18
Sun-Yong Kim, Tomoyuki Mori, Min Fey Chek, Shunji Furuya, Ken Matsumoto, Taisei Yajima, Toshihiko Ogura, Toshio Hakoshima. Structural insights into vesicle amine transport-1 (VAT-1) as a member of the NADPH-dependent quinone oxidoreductase family. Scientific reports. 2021. 11. 1. 2120-2120
Yusuke Watanabe, Daiki Seya, Dai Ihara, Shuhei Ishii, Taiki Uemoto, Atsushi Kubo, Yuji Arai, Yoshie Isomoto, Atsushi Nakano, Takaya Abe, et al. Importance of endothelial Hey1 expression for thoracic great vessel development and its distal enhancer for Notch-dependent endothelial transcription. The Journal of biological chemistry. 2020. 295. 51. 17632-17645

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MISC (81)：

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Patents (4)：

Lectures and oral presentations (19)：

The M project, Mechanical control of Metabolism, Mitochondira and Muscle (Keynote Lecture)
(3rd International Symposium on Mechanobiology, MBI, NUS, Singapore 2017)
代謝を調節する力学場としてのアクチン骨格
(ワークショップ(アクチンが担うメカノシグナリング) 分子生物学会/細胞生物学会合同年会 2017)
力学刺激から考える発生と再生、そして医学展開
(Molecular Cardiovascular Metabolic Conference 神戸ベイシェラトン 2017)
力学刺激から考える生命現象と工学技術による革新
(69回日本細胞生物学会仙台 2017)
A possibility of aging control - an approach from mechanobiology
(加齢研シンポジウム仙台 2017)

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Education (2)：

- 1988 Kyoto University Graduate School, Division of Medical Sciences Physiology
- 1984 Tohoku University Faculty of Medicine

Professional career (1)：

Work history (6)：

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Committee career (5)：

2012 - 2018 JST さきがけ構造生命科学アドバイザー
2018 - 3rd International Symposium on Mechanobiology International Scientific Committee
2018 - 第69回日本細胞生物学会プログラム委員(幹事)
2006 - 2008 Faculty of 1000 member
2008 - 内閣府先端医療特区評価委員

Association Membership(s) (2)：

Faculty of 1000(2006/04-2007/03 論文査読者) , IUBMB(2006/06-2006/06 Young Scientist Award 審査員)

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