Nakamura Yutaka

ナカムラユタカ | Nakamura Yutaka

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www12.plala.or.jp/environ_org_chem/index.html

Research field (4)： Molecular biochemistry , Bioorganic chemistry , Synthetic organic chemistry , Structural/physical organic chemistry

Research keywords (6)： Fluorous Chemistry , Natural Product Synthesis , Synthetic Organic Chemistry , Fluorous Chemistry , Synthetic Organic Chemistry , 天然物合成

Research theme for competitive and other funds (11)：

2020 - 2022 越後白雪茸抽出成分の合成と構造活性相関に関する研究
2020 - 2021 糖質を出発物質としたピロールアルカロイドの全合成研究
2018 - 2019 新潟県産きのこ越後白雪茸Bisidiomycetes-Xより見いだされた新規ピロールアルカロイドの合成研究
2018 - 2019 疎水性タグを用いたペプチド性海洋天然物のミックスチャー合成
2012 - 2016 Synthetic Studies of Cyclic Depsipeptide, Grassypeptolides from Marine Cyanobacteria

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Papers (34)：

Toshio Sakamoto, Ayaka Nishida, Naoki Wada, Yutaka Nakamura, Shinji Sato, Tetsuya Konishi, Seiichi Matsugo. Identification of a Novel Pyrrole Alkaloid from the Edible Mushroom Basidiomycetes-X (Echigoshirayukidake). Molecules. 2020. 25. 21. 4879
Vijayasree V. Giridharan, Vengadeshprabhu Karupppagounder, Somasundaram Arumugam, Yutaka Nakamura, Ashrith Guha, Tatiana Barichello, Joao Quevedo, Kenichi Watanabe, Tetsuya Konishi, Rajarajan A. Thandavarayan. 3,4-Dihydroxybenzalacetone (DBL) Prevents Aging-Induced Myocardial Changes in Senescence-Accelerated Mouse-Prone 8 (SAMP8) Mice. Cells. 2020. 9. 3. 597
Ken Takakura, Shouhei Takatou, Ryoichi Tomiyama, Thuong Manh Le, Dinh Thi Nguyen, Yutaka Nakamura, Tetsuya Konishi, Seiichi Matsugo, Osamu Hori. Inhibition of nuclear factor-κB p65 phosphorylation by 3,4-dihydroxybenzalacetone and caffeic acid phenethyl ester. Journal of Pharmacological Sciences. 2018. 137. 3. 248-255
Ryoichi Tomiyama, Ken Takakura, Shouhei Takatou, Thuong M. Le, Takumi Nishiuchi, Yutaka Nakamura, Tetsuya Konishi, Seiichi Matsugo, Osamu Hori. 3,4-dihydroxybenzalacetone and caffeic acid phenethyl ester induce preconditioning ER stress and autophagy in SH-SY5Y cells. Journal of Cellular Phsiology. 2017. 233. 2. 1671-1684
3,4-dihydroxybenzalacetone protects against Parkinson's disease-related neurotoxin 6-OHDA through Akt/Nrf2/glutathione pathway. J. Cell. Biochem. 2013. 115. 1. 151-160

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MISC (1)：

Seiji Takeuchi, Yutaka Nakamura, Yoshiaki Ohgo, Dennis P. Curran. Catalytic enantioselective protonation of a samarium enolate with fluorous chiral and achiral proton sources in fluorous biphasic systems. Tetrahedron Letters. 1998. 39. 47. 8691-8694

Books (8)：

One-pot multi-substrate screening
2006
フルオラス保護基を用いた海洋天然物の合成
シーエムシー出版 2005
Sections 3.3.2-3.3.4
2005
Under Non-biphasic Conditions
2004 ISBN:9783527307210
Enantioselective Catalysis in Non-biphasic Conditions
2004

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Lectures and oral presentations (66)：

コウホネ(<I>Nuphar japonicum</I>)に含まれるグルコシルセラミド合成酵素阻害物質の単離と、その評価
(第14回東北糖鎖研究会 2020)
水生植物コウホネに含まれるグルコシルセラミド合成酵素阻害活性の性質と阻害物質単離の試み
(第13回東北糖鎖研究会 2019)
新規構造を持つグルコシルセラミド合成酵素阻害物質の探索
(第13回東北糖鎖研究会 2019)
(+)-および(-)-グランジウバリンAの全合成と絶対立体配置の決定
(第76回有機合成化学協会関東支部シンポジウム-新潟(長岡)シンポジウムー 2018)
パキストリドAの提出構造の全合成
(第76回有機合成化学協会関東支部シンポジウム-新潟(長岡)シンポジウムー 2018)

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Education (3)：

1990 - 1993 Kanagawa University Graduate School, Division of Engineering
1988 - 1990 Kanagawa University Graduate School, Division of Engineering
- 1988 Kanagawa University Faculty of Engineering

Professional career (2)：

工学 (神奈川大学)
工学 (神奈川大学)

Work history (12)：

2012/04 - 現在 Niigata University of Pharmacy and Applied Life Sciences Faculty of Applied Life Sciences Department of Applied Life Sciences Professor
2012/04/01 - 現在 Niigata University of Pharmacy and Applied Life Sciences Faculty of Applied Life Sciences
2007/04/01 - 2012/03/31 Niigata University of Pharmacy and Applied Life Sciences Faculty of Applied Life Sciences
2007/04 - 2012/03 Niigata University of Pharmacy and Applied Life Sciences Faculty of Applied Life Sciences Department of Applied Life Sciences Associate Professor
2004/04/01 - 2007/03/31 Niigata University of Pharmacy and Applied Life Sciences Faculty of Applied Life Sciences

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Association Membership(s) (5)：

日本フッ素化学会 , フルオラス科学研究会 , アメリカ化学会 , 有機合成化学協会 , 日本化学会

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