Rchr
J-GLOBAL ID：200901025047008736   Update date: Apr. 09, 2024

Shimoda Nobuyoshi

シモダ ノブヨシ | Shimoda Nobuyoshi
Affiliation and department：
National Center for Geriatrics and Gerontrogy

About National Center for Geriatrics and Gerontrogy


Job title： Chief
Research field  (2)： Systems genomics ,  Genomics
Research keywords  (2)： エピジェネティクス ,  epigenetics
Research theme for competitive and other funds  (3)：
  • 2018 - 2021 Elucidation of zebrafish Dnmt3aa target genomic regions and region-specific factors in hematopoiesis
  • 2017 - 2020 Development of a new mouse model to induce Alzheimer's pathology
  • 2016 - 2019 Mechanism of transgene silencing that is visualized in zebrafish embryos
Papers (30)：
  • Yuya Asanomi, Tetsuaki Kimura, Nobuyoshi Shimoda, Daichi Shigemizu, Shumpei Niida, Kouichi Ozaki. CRISPR/Cas9-mediated knock-in cells of the late-onset Alzheimer's disease-risk variant, SHARPIN G186R, reveal reduced NF-κB pathway and accelerated Aβ secretion. Journal of human genetics. 2024
  • Fumihiko Yasuno, Yasuyuki Kimura, Aya Ogata, Hiroshi Ikenuma, Junichiro Abe, Hiroyuki Minami, Takashi Nihashi, Kastunori Yokoi, Saori Hattori, Nobuyoshi Shimoda, et al. Neuroimaging biomarkers of glial activation for predicting the annual cognitive function decline in patients with Alzheimer's disease. Brain, behavior, and immunity. 2023
  • Masaki Shirai, Nobuyoshi Shimoda, Haruko Takahashi, Kazuya Takayama, Yutaka Kikuchi. Microarray transcriptome datasets of maternal-zygotic DNA methyltransferase 3aa-/- zebrafish during early developmental stages. Data in Brief. 2023. 47. 108967-108967
  • Fumihiko Yasuno, Atsushi Watanabe, Yasuyuki Kimura, Yumeka Yamauchi, Aya Ogata, Hiroshi Ikenuma, Junichiro Abe, Hiroyuki Minami, Takashi Nihashi, Kastunori Yokoi, et al. Estimation of blood-based biomarkers of glial activation related to neuroinflammation. Brain, Behavior, & Immunity - Health. 2022. 26. 100549-100549
  • Fumihiko Yasuno, Yasuyuki Kimura, Aya Ogata, Hiroshi Ikenuma, Junichiro Abe, Hiroyuki Minami, Takashi Nihashi, Kastunori Yokoi, Saori Hattori, Nobuyoshi Shimoda, et al. Involvement of inflammation in the medial temporal region in the development of agitation in Alzheimer's disease: an in vivo positron emission tomography study. Psychogeriatrics. 2022
ｍore...
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