Nakamura Seikou

ナカムラセイコウ | Nakamura Seikou

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： https://www.kyoto-phu.ac.jp/education_research/laboratory/?c=laboratory_view&pk=4

Research field (2)： Environmental and pharmaceutical development resources , Pharmaceuticals - chemistry and drug development

Research keywords (2)：生薬学・天然物化学 , Natural Product Pharmacology

Research theme for competitive and other funds (15)：

2023 - 2027 Construction of pseudo-natural products using enzymes from medicinal plants and development of therapeutic agents for glioblastoma
2021 - 2024 糖化タンパク質による神経新生阻害をターゲットとする新規認知症治療薬シード探索研究
2020 - 2024 がん化学療法抵抗性改善機能に基づく天然由来新規医薬品シーズの開拓
2020 - 2023 Elucidation of the pathogenesis of pulmonary fibrosis mediated by dopamine receptors and development of novel therapeutic agents
2020 - 2023 Development of antiviral agents against herpes simplex virus from medicinal plants based on the control of aciclovir phosphorylation enzyme

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Papers (200)：

Kousuke Araki, Minami Hara, Shohei Hamada, Takahiro Matsumoto, Seikou Nakamura. Antiproliferative Activities of Cynaropicrin and Related Compounds against Cancer Stem Cells. Chemical & pharmaceutical bulletin. 2024. 72. 2. 200-208
Seikou Nakamura. Development of Functional Compounds Using Chemically Unstable Compounds Obtained from Medicinal Plants. YAKUGAKU ZASSHI. 2024. 144. 1. 21-26
Takumi Inoue, Moe Ota, Yui Amijima, Haru Takahashi, Shohei Hamada, Seikou Nakamura, Yusuke Kobayashi, Takahiro Sasamori, Takumi Furuta. Dual Chalcogen-Bonding Interactions for the Conformational Control of Urea**. Chemistry - A European Journal. 2023. 29. 60
Junko Tsukioka, Tomoka Takami, Yuki Ario, Seikou Nakamura. Production of Dihydroisocoumarins by Callus Induction from Hydrangea macrophylla var. thunbergii Leaves. Chemical and Pharmaceutical Bulletin. 2023. 71. 11. 832-837
Junko Tsukioka, Yutaro Ohki, Momona Nakao, Seikou Nakamura. Quantitative analysis of taxiphyllin, a cyanogenic glycoside, in the leaves of Hydrangea macrophylla var. thunbergii. Journal of Natural Medicines. 2023. 77. 4. 978-985

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MISC (130)：

吉谷優奈, 山下遥加, 髙橋彩乃, 小堀由郁子, 玉野優果, 鵜川孔汰, 松本崇宏, 松田久司, 中村誠宏. ショウガ科Boesenbergia rotunda含有シクロヘキセニルカルコン panduratin A の合成とがん幹細胞に対する増殖抑制評価. 日本生薬学会第68回年会オンライン開催. 2022
中村誠宏. 薬用食品由来成分を利用した難治性疾患予防・治療薬の開発研究. 日本生薬学会第68回年会オンライン開催. 2022
Identification for High-affinity Proteins to Sesquiterpene Lactone, Cynaropicrin, with Cytotoxicity and Inhibitory Activity against Nitric Oxide Production in RAW264.7 Cells. 10th Asian Association of Schools of Pharmacy (AASP) Conference 2022. 2022
中嶋聡一, 中嶋聡一, 中嶋聡一, 青木麻琴, 森川敏生, 中村誠宏, 松田久司, 松田久司. Effects of flavonoids on suppression of neurite outgrowth by glycated proteins, and search for motif on target mRNAs. 日本薬学会年会要旨集(Web). 2022. 142nd
森川敏生, 長友暁史, 坂本裕介, 萬瀬貴昭, 中嶋聡一, 中嶋聡一, 中村誠宏, 二宮清文, 二宮清文, 吉川雅之, et al. Biofunctional khellactone-type coumarins from the leaves of Angelica furcijuga Kitagawa. 香料・テルペンおよび精油化学に関する討論会講演要旨集. 2022. 66th

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Patents (1)：

Books (3)：

Lectures and oral presentations (21)：

オオツヅラフジ (Sinomenium acutum) 茎および根茎中のがん幹細胞増殖抑制活性物質の探索
(日本薬学会第 143 年会 2023)
薬用植物から得られる化学的に不安定な成分を使用した機能性化合物の開発研究
(日本薬学会第 143 年会 2023)
Bacopa monniera に含有される Aβ結合物質 plantainoside B による Aβ凝集体の検出と神経保護作用
(日本薬学会第 143 年会 2023)
がん幹細胞に対する駆逐作用を有する染料アカネ (Rubia argyi, 根部) 由来成分の探索研究
(日本薬学会第 143 年会 2023)
既存の抗がん薬とは異なる作用機序を有する薬用植物由来抗がん薬の開発研究 -生細胞イメージングシステムを利用した生薬川骨由来成分の抗がん作用の機序解析-
(日本薬学会第 143 年会 2023)

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Education (5)：

1999 - 2003 Kyoto Pharmaceutical University Graduate School of Pharmaceutical Sciences
1997 - 1999 Kyoto Pharmaceutical University Graduate School of Pharmaceutical Sciences
- 1999 Kyoto Pharmaceutical University Graduate School, Division of Pharmaceutical Sciences
1994 - 1997 Kyoto Pharmaceutical University Pharmaceutical Sciences
- 1997 Kyoto Pharmaceutical University Faculty of Pharmaceutical Science

Professional career (1)：

Work history (4)：

2013/10 - 現在 Kyoto Pharmaceutical University Pharmacognosy Associate Professor
2007/04 - 2013/09 Kyoto Pharmaceutical University Pharmacognosy Assistant professor
2005/06 - 2007/03 Kyoto Pharmaceutical University Pharmacognosy Assiant professor
2003/04 - 2005/05 The University of North Carolina at Chapel Hill School of Pharmacy Postdoctoral Fellow

Committee career (3)：

Association Membership(s) (3)：

日本生薬学会 , 日本薬学会 , MEDICAL AND PHARMACEUTICAL SOCIETY FOR WAKAN-YAKU

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