Okamoto Hirokazu

オカモトヒロカズ | Okamoto Hirokazu

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www-yaku.meijo-u.ac.jp/kenkyu/drug-deli/
Research theme for competitive and other funds (6)：

2016 - 2019 免疫系ヒト化マウスを用いた癌免疫回避機構解明と次世代遺伝子ワクチンによる克服戦略
2015 - 2019 Development of novel dry powder inhalers with high performance which disintegrate and well in the lungs
2014 - 2018 Development of Novel Dry siRNA Powders for Inhalation Based on Spontaneous Lipid Nanoparticle Constitution in Lung
2010 - 2012 Trial to suppress gene expression in airway by intratracheal administration of dry-powdered siRNA
2010 - 2011 DEVELOPMENT OF PERSONALIZED ANTICANCER THERAPY BY INHALABLE DRY POWDER BASED ON NONINVASIVE LUNG DEPOSITION MONITORING

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Papers (100)：

Tomoyuki Okuda, Maki Okazaki, Akihiko Hayano, Hirokazu Okamoto. Stability of Naked Nucleic Acids under Physical Treatment and Powder Formation: Suitability for Development as Dry Powder Formulations for Inhalation. Pharmaceutics. 2023. 15. 12. 2786-2786
Naomi Muramatsu, Misa Ichikawa, Tomoko Katagiri, Yumi Taguchi, Takashi Hatanaka, Tomoyuki Okuda, Hirokazu Okamoto. p53 dry gene powder enhances anti-cancer effects of chemotherapy against malignant pleural mesothelioma. Gene Therapy. 2023
奥田知将, 平大樹, 岡本浩一. 吸入剤と関連試験法. 薬剤学. 2022. 82. 4. 188-194
Misa Ichikawa, Naomi Muramatsu, Wataru Matsunaga, Takahiro Ishikawa, Tomoyuki Okuda, Hirokazu Okamoto, Akinobu Gotoh. Effects of inhalable gene transfection as a novel gene therapy for non-small cell lung cancer andmalignant pleural mesothelioma. Sci. Rep. 2022. 12. 8634
中村敏史, 山本雅史, 島浩一郎, 池上信昭, 岡本浩一. 薬剤師外来における吸入指導がもたらす喘息患者の吸入継続率向上と増悪抑制効果. 日本病院薬剤師会雑誌. 2021. 57. 9. 981-985

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MISC (32)：

岡本浩一, 奥田知将. ヒアルロン酸ゲルを用いたNSAIDs 徐放性膝関節腔内注射剤の開発. 名城大学総合研究所紀要. 2021. 26. 99-102
奥田知将, 岡本浩一. 模擬肺液中での自己組織化siRNA/脂質ナノ粒子の物性・機能. 名城大学総合研究所紀要. 2021. 26. 131-134
奥田知将, 岡本浩一. アデノ随伴ウイルスベクターによる吸入遺伝子治療を志向した基盤研究. 名城大学総合研究所紀要. 2020. 25. 149-152
奥田知将, 岡本浩一. 自己組織化ナノ粒子型吸入粉末剤の実用化を目指した基礎研究. 名城大学総合研究所紀要. 2019. 24. 137-140
奥田知将, 岡本浩一. 注射用siRNA/脂質ナノ粒子の自己組織化に適した凍結乾燥製剤の開発. 名城大学総合研究所紀要. 2018. 23. 191-194

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Professional career (1)：

薬学博士 (京都大学)

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