Sado Takashi

サドタカシ | Sado Takashi

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： https://sites.google.com/view/kindai-epigenetics/

Research field (1)： Genetics

Research keywords (7)：クロマチン , ノンコーディングRNA , エピジェネティクス , X染色体不活性化 , Epigenetics , DNA Methylation , X-inactivation

Research theme for competitive and other funds (21)：

2020 - 2024 生命発動と器官発生・制御に関わるヒト受精胚分子機序の解明
2017 - 2020 Elucidation of oocyte molecular mechanism on imprinted X chromosome inactivation enabling a sequential development
2017 - 2019 ヘテロクロマチン形成におけるXist RNA作動エレメントの役割
2016 - 2017 ヘテロクロマチン形成とクロマチン環境
2014 - 2015 染色体活性制御と偽ヘテロクロマチン化の相関

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Papers (57)：

Rawin Poonperm, Saya Ichihara, Hisashi Miura, Akie Tanigawa, Koji Nagao, Chikashi Obuse, Takashi Sado, Ichiro Hiratani. Replication dynamics identifies the folding principles of the inactive X chromosome. Nature Structural & Molecular Biology. 2023. 30. 8. 1224-1237
Saya Ichihara, Koji Nagao, Takehisa Sakaguchi, Chikashi Obuse, Takashi Sado. SmcHD1 underlies the formation of H3K9me3 blocks on the inactive X chromosome in mice. Development. 2022
Ruka Matsuura, Tatsuro Nakajima, Saya Ichihara, Takashi Sado. Ectopic Splicing Disturbs the Function of Xist RNA to Establish the Stable Heterochromatin State. Frontiers in Cell and Developmental Biology. 2021. 9
Takashi Sado. Does XIST safeguard against sex-biased human diseases?. Molecular cell. 2021. 81. 8. 1598-1600
Hiroaki Ohishi, Wan Kin Au Yeung, Motoko Unoki, Kenji Ichiyanagi, Kei Fukuda, Shoji Maenohara, Kenjiro Shirane, Hatsune Chiba, Takashi Sado, Hiroyuki Sasaki. Characterization of genetic-origin-dependent monoallelic expression in mouse embryonic stem cells. Genes to cells : devoted to molecular & cellular mechanisms. 2020. 25. 1. 54-64

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MISC (36)：

Koji Nagao, Shin-Ya Isobe, Yoshi-Nobu Ohkubo, Yoko Hayashi-Takanaka, Hiroshi Kimura, Takashi Sado, Chikashi Obuse. Constitution of Higher Order Heterochromatin Structure Based on Epigenetic Code. GENES & GENETIC SYSTEMS. 2016. 91. 6. 318-318
Takashi Sado. X chromosome inactivation in the mouse. GENES & GENETIC SYSTEMS. 2016. 91. 6. 320-320
Tatsuro Nakajima, Yuko Hoki, Hiroyuki Sasaki, Takashi Sado. The defects in X-inactivation by partially dysfunctional Xist allele. GENES & GENETIC SYSTEMS. 2015. 90. 6. 390-390
Hiroaki Ohishi, Motoko Unoki, Kei Fukuda, Shoji Maenohara, Kyohei Hori, Hatsune Chiba, Takashi Sado, Hiroyuki Sasaki. Transcriptional regulation of monoallelically expressed genes in ground-state embryonic stem cells. GENES & GENETIC SYSTEMS. 2015. 90. 6. 369-369
Yuki Sakakibara, Hiroyuki Sasaki, Marnie Blewitt, Takashi Sado. X chromosome inactivation in the mouse embryos deficient for SmcHD1. GENES & GENETIC SYSTEMS. 2015. 90. 6. 390-390

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Books (4)：

X-Chromosome Inactivation
Human Press (Springer Nature) 2018 ISBN:9781493987658
Encyclopedia of Reproduction 2nd Edition
Academic Press (Elsevier) 2018 ISBN:9780128118993
エピジェネティクス実験スタンダード
羊土社 2017 ISBN:9784758101998
遺伝子発現制御機構クロマチン,転写制御,エピジェネティクス
東京化学同人 2017 ISBN:9784807909179

Education (3)：

Professional career (1)：

Work history (4)：

2014/04 - 現在 Kindai University Faculty of Agriculture
2009/05 - 2014/03 Medical Institute of Bioregulation, Kyushu Univ. Associate professor
2000/04 - 2009/04 The Graduate University for Advanced Studies
1999/05 - 2009/04 National Institute of Genetics

Committee career (2)：

Awards (1)：

Association Membership(s) (6)：

日本エピジェネティクス研究会 , 日本RNA学会 , 日本分子生物学会 , 日本遺伝学会 , The Molecular Biology Society of Japan , The Genetics Society of Japan

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