Rchr
J-GLOBAL ID：200901025716334202
Update date: Jan. 30, 2024
Sohda Miwa
Sohda Miwa
Affiliation and department：
Nagasaki International University
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Detailed information
Research field (3)：
Pharmaceuticals - health and biochemistry
, Oral medicine (pathology)
, Cell biology
Research keywords (4)：
intracellular trafficking
, organelle
, olfactory receptor
, sjogren's syndrome
Research theme for competitive and other funds (13)：
2016 - 2019 シェーグレン症候群におけるTLR3活性化とその制御
2011 - 2015 Role of golgins, proteins for Golgi homeostasis, in secretory membrane traffic.
2010 - 2013 シェーグレン症候群の酸化ストレス制御による口腔乾燥症状緩和に向けて
2009 - 2011 Analysis of molecular mechanism of hypophosphatasia
2008 - 2010 Golgi structure and golgins
2005 - 2007 小胞体-ゴルジ体間小胞輸送における輸送小胞の運搬機構
2003 - 2005 ゴルジ体における輸送小胞繋留機構の解析
2003 - 2004 Identification and characterization of proteins required for the Golgi structure
1999 - 2001 小胞輸送因子p115をリン酸化する酵素の解析
1997 - 1998 Analysis of high molecular proteins localized at the cytoplasmic side of the Golgi apparatus
1996 - 1996 ゴルジ装置細胞質側に局在する高分子蛋白質ファミリーの解析
1995 - 1996 ゴルジ装置細胞質側に局在する新しい蛋白質ファミリーの解析
1994 - 1994 ゴルジ装置局在蛋白質CGP360の性質、機能に関する研究
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Papers (34)：
Keiichi Komaru, Yasuhito Satou, Hiba A. Al-Shawafi, Natsuko Numa-Kinjoh, Miwa Sohda, Kimimitsu Oda. Glycosylation-deficient mutations in tissue-nonspecific alkaline phosphatase impair its structure and function and are linked to infantile hypophosphatasia. FEBS JOURNAL. 2016. 283. 6. 1168-1179
Miwa Sohda, Yoshio Misumi, Kimimitsu Oda. TNF alpha triggers release of extracellular vesicles containing TNFR1 and TRADD, which can modulate TNF alpha responses of the parental cells. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 2015. 587. 31-37
Natsuko Numa-Kinjoh, Keiichi Komaru, Yoko Ishida, Miwa Sohda, Kimimitsu Oda. Molecular phenotype of tissue-nonspecific alkaline phosphatase with a proline (108) to leucine substitution associated with dominant odontohypophosphatasia. MOLECULAR GENETICS AND METABOLISM. 2015. 115. 4. 180-185
Ryuichi Ishida, Akitsugu Yamamoto, Kazuhisa Nakayama, Miwa Sohda, Yoshio Misumi, Takuo Yasunaga, Nobuhiro Nakamura. GM130 is a parallel tetramer with a flexible rod-like structure and N-terminally open (Y-shaped) and closed (I-shaped) conformations. FEBS JOURNAL. 2015. 282. 11. 2232-2244
Miwa Sohda, Yoshio Misumi, Shigenori Ogata, Shotaro Sakisaka, Shinichi Hirose, Yukio Ikehara, Kimimitsu Oda. Trans-Golgi protein p230/golgin-245 is involved in phagophore formation. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2015. 456. 1. 275-281
ｍore...
MISC (10)：
相田美和, 吉村建. シェーグレン症候群-発症におけるTLR3の役割を中心として. 月刊アレルギーの臨床. 2018. 518. 977-979
織田公光, 沼ー金城 奈津子, 相田美和, 小丸圭一, 網塚憲生. アルカリフォスファターゼと低フォスファターゼ症. Clinical Calcium. 2014. 24. 2. 77-83
織田公光, 沼(金城)奈津子, 相田美和, 小丸圭一, 網塚憲生. バイオミネラリゼーション~結晶学から臨床まで~アルカリフォスファターゼと低フォスファターゼ症. Clinical Calcium. 2014. 24. 2. 233-239
Sohda, M, Misumi, Y, Yamamoto, A, Yano, A, Nakamura, N, Ikehara, Y. Identification and characterization of a novel Golgi protein, GCP60, that interacts with the integral membrane protein giantin. J Biol Chem. 2001. 276. 45298-45306
MISUMI Y, SOHDA M, TASHIRO A, SATO H, IKEHARA Y. An essential cytoplasmic domain for the Golgi localization of Coiled-coil proteins with a COOH-terminal membrane anchor. J Biol Chem. 2001. 276. 9. 6867-6873
ｍore...
Education (1)：
- 1987 Kyushu University School of Pharmaceutical Sciences
Professional career (1)：
医学
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