Igawa Kazunobu

イガワカズノブ | Igawa Kazunobu

Affiliation and department：
Homepage URL (1)： https://www.kumadai-igawa.info/

Research field (2)： Synthetic organic chemistry , Structural/physical organic chemistry

Research theme for competitive and other funds (21)：

2023 - 2026 Development of Silicon Containing Biomolecule based on Stereocontrol of Asymmetric Silicon
2020 - 2025 Development of DYASIN: Novel Approach to Enantioenriched Chiral Molecules
2020 - 2023 GSK-3活性化作用に基づいた心臓線維化抑制薬開発に向けた基盤研究
2020 - 2023 キラルケイ素分子の精密合成法開発と新規生物活性分子創製への展開
2021 - 2022 Design of Bifunctional Selenium Catalysts and Its Application to Precise Organic Synthesis

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Papers (86)：

Akihiro Kuroo, Kazunobu Igawa, Katsuhiko Tomooka. Stereoselective synthesis of multi-functionalized chiral silacyclopentanes. Chemistry Letters. 2024
Takehiro Kishigami, Shin Ishikane, Masaki Arioka, Kazunobu Igawa, Yosuke Nishimura, Fumi Takahashi-Yanaga. 2,5-Dimethyl-celecoxib induces early termination of inflammatory responses by transient macrophage accumulation and inhibits the progression of cardiac remodeling in a mouse model of cryoinjury-induced myocardial infarction. Journal of Pharmacological Sciences. 2024. 154. 2. 97-107
Takahiro Moriyama, Makoto Yoritate, Naoki Kato, Azusa Saika, Wakana Kusuhara, Shunsuke Ono, Takahiro Nagatake, Hiroyuki Koshino, Noriaki Kiya, Natsuho Moritsuka, et al. Linkage-Editing Pseudo-Glycans: A Reductive α-Fluorovinyl-C-Glycosylation Strategy to Create Glycan Analogs with Altered Biological Activities. Journal of the American Chemical Society. 2024. 146. 3. 2237-2247
Yuki Arakawa, Takuma Shiba, Kazunobu Igawa. Selenium-linked cyanobiphenyl-based liquid crystal dimers: the effects of chalcogen linkage and spacer length on the twist-bend nematic phase. Liquid Crystals. 2024
Masaki Arioka, Fumi Seto-Tetsuo, Takeru Inoue, Koichi Miura, Shin Ishikane, Kazunobu Igawa, Katsuhiko Tomooka, Fumi Takahashi-Yanaga, Toshiyuki Sasaguri. Differentiation-inducing factor-1 reduces lipopolysaccharide-induced vascular cell adhesion molecule-1 by suppressing mTORC1-S6K signaling in vascular endothelial cells. Life sciences. 2023. 335. 122278-122278

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MISC (54)：

臼井一晃, 成田望実, 江藤亮介, 飯塚直子, 梅野智大, 井川和宣, 友岡克彦, 今井喜胤, 唐澤悟. Oxidation of phosphine in the inner rim of helicene and chiroptical properties. 基礎有機化学討論会要旨集. 2022. 32nd (CD-ROM)
Kazunobu Igawa, Kazuhiro Uehara, Yuuya Kawasaki, Katsuhiko Tomooka. Stereochemical study on planar-chiral cyclic molecules using polysaccharide-based column chromatography. Chirality. 2022
Kazunobu Igawa, Yuuya Kawasaki, Yusuke Ano, Takeru Kashiwagi, Kouhei Ogawa, Jun Ichi Hayashi, Ryota Morita, Yukari Yoshioka, Kazuhiro Uehara, Katsuhiko Tomooka. Preparation of enantioenriched chiral organic molecules by dynamic asymmetric induction from a outer chiral source. Chemistry Letters. 2019. 48. 7. 726-729
山田泰之, 三原のぞみ, 森田健太郎, 高谷光, 北河康隆, 井川和宣, 友岡克彦, 田中健太郎. 超分子会合体形成反応を利用した窒素架橋鉄ポルフィリノイド二核錯体型エタン酸化触媒の活性化. ホスト-ゲスト・超分子化学シンポジウム講演要旨集. 2018. 16th
Kazunobu Igawa. Asymmetric Synthesis of Chiral Silicon Molecules and Stereoselective Transformations Thereof. JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN. 2017. 75. 9. 6-16

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Patents (8)：

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Lectures and oral presentations (48)：

軸不斉を有するナフチルイソキノリン N-オキシド誘導体の合成と立体化学的安定性に関する研究
(日本化学会第104春期年会 2024)
ナフトベンゾフラノール誘導体の位置選択的ハロゲン化とクロスカップリングによる新規ヘテロビアリール類の合成
(日本化学会第104春期年会 2024)
分子内C-Hアミノ化を鍵反応とする螺旋環内縁部に置換基を有するアザオキサ[6]ヘリセンの合成
(日本化学会第104春期年会 2024)
1,1’-ビアズレン骨格で構成される不斉ヘリセン化合物とそのカチオンラジカルの構造と性質
(日本化学会第104春期年会 2024)
動的キラルなN-アリールアミドの合成と変換
(日本化学会第104春期年会 2024)

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Education (2)：

- 2003 Tokyo Institute of Technology Science of Engineering
- 2003 Tokyo Institute of Technology Graduate School, Division of Science and Engineering Applied Chemistry

Professional career (1)：

Doctor of Engineering (Tokyo Institute of Technology)

Work history (6)：

2022/09 - 現在 Kumamoto University
2007/04 - 2022/08 Kyushu University Institute for Materials Chemistry and Engineering
2004/12 - 2007/03 - 東京工業大学大学院理工学研究科助手
2003 - 2004 万有製薬株式会社合成技術研究所研究員
2003 - 2004 Banyu Pharmaceutical Co., LTD. Process R & D Researcher

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Awards (10)：

2023/12 - The 16th International Conference on Cutting-Edge Organic Chemistry in Asia Asian Core Program Lectureship Award (Taiwan) Chemistry of Chiral Silicon Molecules: Approaches to Chiral Silacarboxylic Acids and Their Ester Derivatives
2016 - 宇部興産学術振興財団宇部興産学術振興財団第57回学術奨励賞
2014 - ケイ素化学協会ケイ素化学協会奨励賞
2014 - 万有生命科学振興国際交流財団 Banyu Chemist Award (2014)
2012 - 日本化学会若い世代の特別講演賞

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Association Membership(s) (6)：

ケイ素化学協会 , 有機合成化学協会 , 日本化学会 , The Society of Silicon Chemistry Japan , The Society of Synthetic Organic Chemistry, Japan , The Chemical Society of Japan

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