Rchr
J-GLOBAL ID:200901026809819180   Update date: Feb. 01, 2024

Itoh Toshiki

イトウ トシキ | Itoh Toshiki
Affiliation and department:
Job title: Professor
Research field  (1): Functional biochemistry
Research theme for competitive and other funds  (18):
  • 2022 - 2025 Osteoclast fusion mechanism based on plasma membrane curvature and tension
  • 2019 - 2022 A feedback mechanism between the plasma membrane and the actin cytoskeleton underneath during cell migration
  • 2016 - 2019 Role of plasma membrane tension in cell polarity
  • 2014 - 2019 Molecular mechanisms of cell competition between normal and transformed cells
  • 2015 - 2018 Structural analysis of membrane-deforming SYLF domain proteins
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Papers (55):
  • Toshiki Itoh, Kazuya Tsujita. Exploring membrane mechanics: The role of membrane-cortex attachment in cell dynamics. Current Opinion in Cell Biology. 2023. 81. 102173-102173
  • Kaori Kanemaru, Makoto Shimozawa, Manabu Kitamata, Rikuto Furuishi, Hinako Kayano, Yui Sukawa, Yuuki Chiba, Takatsugu Fukuyama, Junya Hasegawa, Hiroki Nakanishi, et al. Plasma membrane phosphatidylinositol (4,5)-bisphosphate is critical for determination of epithelial characteristics. Nature Communications. 2022. 13. 1
  • Shinya Yuge, Koichi Nishiyama, Yuichiro Arima, Yasuyuki Hanada, Eri Oguri-Nakamura, Sanshiro Hanada, Tomohiro Ishii, Yuki Wakayama, Urara Hasegawa, Kazuya Tsujita, et al. Mechanical loading of intraluminal pressure mediates wound angiogenesis by regulating the TOCA family of F-BAR proteins. Nature Communications. 2022. 13. 1
  • Kazuya Tsujita, Reiko Satow, Shinobu Asada, Yoshikazu Nakamura, Luis Arnes, Keisuke Sako, Yasuyuki Fujita, Kiyoko Fukami, Toshiki Itoh. Homeostatic membrane tension constrains cancer cell dissemination by counteracting BAR protein assembly. Nature Communications. 2021. 12. 1
  • Tomoko Kamasaki, Yumi Miyazaki, Susumu Ishikawa, Kazuya Hoshiba, Keisuke Kuromiya, Nobuyuki Tanimura, Yusuke Mori, Motosuke Tsutsumi, Tomomi Nemoto, Ryota Uehara, et al. FBP17-mediated finger-like membrane protrusions in cell competition between normal and RasV12-transformed cells. iScience. 2021. 24. 9. 102994-102994
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MISC (46):
Books (2):
  • リッピンコットシリーズ イラストレイテッド細胞分子生物学 / 第3章 生体膜、第4章 細胞骨格
    丸善出版 2012
  • タンパク質実験ハンドブック / タンパク質実験ハンドブック
    羊土社 2010
Lectures and oral presentations  (88):
  • DA-Rafは細胞膜と活性化Rasに結合することによりRas-ERK経路の全体的抑制因子として機能する
    (日本生化学会大会(Web) 2021)
  • Regulation of Cell Membrane Tension by Membrane Curvature-Inducing Proteins
    (日本細胞生物学会大会(Web) 2021)
  • 67kDaラミニンレセプターはビタミンEとの結合によりパルミトイル化修飾を受ける
    (日本生化学会大会プログラム・講演要旨集 2020)
  • 生体膜の変形が制御するバイオロジー 膜曲率誘導タンパク質による細胞膜の張力恒常性維持機構
    (日本生化学会大会プログラム・講演要旨集 2020)
  • 細胞接着と細胞膜から見たメカノ細胞生物学 細胞膜張力と膜変形タンパク質によるがん細胞運動・浸潤の制御
    (日本細胞生物学会大会講演要旨集 2020)
more...
Education (3):
  • 1994 - 1999 The University of Tokyo Graduate School of Science Department of Biophysics and Biochemistry
  • 1992 - 1994 The University of Tokyo Faculty of Science Department of Biophysics and Biochemistry
  • 1990 - 1992 The University of Tokyo
Professional career (1):
  • 博士(理学) (東京大学)
Work history (6):
  • 2013/01 - 現在 Kobe University Biosignal Research Center
  • 2007/04 - 2012/12 Kobe University Graduate School of Medicine
  • 2005/02 - 2007/03 The University of Tokyo The Institute of Medical Science
  • 2003/06 - 2005/01 Yale University School of Medicine Postdoctoral fellow
  • 2000/01 - 2003/05 The University of Tokyo The Institute of Medical Science
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Committee career (3):
  • 2015 - 現在 日本細胞生物学会 代議員
  • 2015 - 現在 日本生化学会 評議員
  • 2013 - 現在 日本脂質生化学会 幹事
Awards (1):
  • 2009/10 - 社団法人日本生化学会 日本生化学会奨励賞 エンドサイトーシスにおける細胞膜の形状制御機構
Association Membership(s) (5):
THE JAPANESE CANCER ASSOCIATION ,  THE JAPANESE CONFERENCE ON THE BIOCHEMISTRY OF LIPIDS ,  JAPAN SOCIETY FOR CELL BIOLOGY ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE BIOCHEMICAL SOCIETY
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