Rchr
J-GLOBAL ID：200901026920411085
Update date: Mar. 11, 2024
Matsuzaki Takanobu
マツザキ タカノブ | Matsuzaki Takanobu
Affiliation and department：
Job title：
Associate Director
Research field (2)：
Pharmacology
, Clinical pharmacy
Research keywords (5)：
PBPK model
, Drug interactions
, Pharmacokinetics
, トランスポーター
, 腎障害
Research theme for competitive and other funds (2)：
- 2003 - 2007 急性腎不全モデルラットにおける薬物トランスポータ群の発現変動解析
- 2003 - 2007 Analysis of drug transporters in rats with acute renal failure.
Papers (21)：
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Yasuto Kido, Isamu Nanchi, Takanobu Matsuzaki, Ryosuke Watari, Hayato Kiyohara, Naomi Seki, Tomohiko Okuda. Prediction of drug-drug interaction risk of P-glycoprotein substrate in drug discovery. Drug Metabolism and Pharmacokinetics. 2024
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Ryosuke Watari, Hiromi Sawada, Hiroshi Hashimoto, Yasuyuki Kasai, Ryoko Oka, Ryosuke Shimizu, Takanobu Matsuzaki. Utility of Coproporphyrin-I Determination in First-in-Human Study for Early Evaluation of OATP1B Inhibitory Potential Based on Investigation of Ensitrelvir, an Oral SARS-CoV-2 3C-Like Protease Inhibitor. Journal of Pharmaceutical Sciences. 2024
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Shimizu R, Sonoyama T, Fukuhara T, Kuwata A, Matsuzaki T, Matsuo Y, Kubota R. Evaluation of the Drug-Drug Interaction Potential of Ensitrelvir Fumaric Acid with Cytochrome P450 3A Substrates in Healthy Japanese Adults. Clinical drug investigation. 2023
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Shimizu R, Matsuzaki T, Oka R, Sonoyama T, Fukuhara T, Kuwata A, Matsuo Y, Kubota R. Evaluation of drug-drug interactions of ensitrelvir, a SARS-CoV-2 3CL protease inhibitor, with transporter substrates based on in vitro and a clinical study. Journal of clinical pharmacology. 2023
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Yasuto Kido, Isamu Nanchi, Yasuyuki Fusamae, Takanobu Matsuzaki, Takanori Akazawa, Hiromi Sawada, Makoto Iwasaki, Kimiko Nishida, Eiichi Tsuchiya, Tomohiko Okuda. Species difference in brain penetration of P-gp and BCRP substrates among monkey, dog and mouse. Drug metabolism and pharmacokinetics. 2022. 42. 100426-100426
ｍore...
MISC (5)：
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泉 裕一郎, 青柳 利紀, 廣山 眞巳, 松崎 尊信, 安岡 有紀子, 河原 克雅, 斉藤 秀之, 冨田 公夫, 野々口 博史, 田上 昭人. 腎マクラデンサ細胞内バソプレッシンV1a受容体を介したレニン-アンジオテンシン-アルドステロン系の調節. 日本内分泌学会雑誌. 2008. 84. 2. 691-691
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泉 裕一郎, 青柳 利紀, 廣山 眞巳, 松崎 尊信, 安岡 有紀子, 三部 篤, 宮崎 博喜, 藤原 葉子, 中山 裕史, 江田 幸政, et al. 腎マクラデンサ細胞内バソプレッシンV1a受容体を介したレニン-アンギオテンシン-アルドステロン系の調節. 日本腎臓学会誌. 2008. 50. 3. 312-312
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松崎 尊信, 吉留 佳奈子, 森崎 崇文, 渡邊 博志, 濱田 哲暢, 野々口 博史, 江田 幸政, 冨田 公夫, 齋藤 秀之. 虚血再灌流・急性腎不全ラットにおける尿細管薬物トランスポータの発現変動解析. 薬剤学: 生命とくすり. 2006. 66. Suppl. 233-233
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Iwakiri Maria, Matsuzaki Takanobu, Yoshitome Kanako, Watanabe Hiroshi, Hamada Akinobu, Saito Hideyuki. REGULATION OF RENAL ORGANIC ANION TRANSPORTER EXPRESSIONS IN RAT KIDNEY ASSOCIATED WITH STREPTOZOTOCIN-INDUCED DIABETES MELLITUS. Abstracts of Annual meeting of Japanese Society for the Study of Xenobiotics. 2006. 21. 0. 340-340
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Yoshitome Kanako, Matsuzaki Takanobu, Watanabe Hiroshi, Hamada Akinobu, Saito Hideyuki. EFFECT OF HYPOMAGNESEMIA ON THE EXPRESSION AND FUNCTION OF ORGANIC ANION TRANSPORTERS, rOAT1 AND rOAT3, IN CISPLATIN-TREATED RAT KIDNEY. Abstracts of Annual meeting of Japanese Society for the Study of Xenobiotics. 2006. 21. 0. 263-263
Education (4)：
- 2017 - 2018 University of Manchester Centre for Applied Pharmacokinetic Research (CAPKR)
- 2005 - 2008 Kumamoto University Graduate School of Pharmaceutical Sciences
- 2003 - 2005 Kumamoto University Graduate School of Pharmaceutical Sciences
- 1999 - 2003 Kumamoto University School of Pharmacy
Work history (1)：
Association Membership(s) (1)：
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