Rchr
J-GLOBAL ID：200901027480766133   Update date: Feb. 29, 2024

Nakata Susumu

ナカタ ススム | Nakata Susumu
Affiliation and department：
Kyoto Pharmaceutical University

About Kyoto Pharmaceutical University


Homepage URL  (1)： http://labo.kyoto-phu.ac.jp/oncology/
Research field  (1)： Tumor biology
Research keywords  (5)： gastrointestinal cancer ,  glioblastoma ,  cancer metabolic reprogramming ,  cancer stem cells ,  cancer research
Research theme for competitive and other funds  (14)：
  • 2023 - 2027 Construction of pseudo-natural products using enzymes from medicinal plants and development of therapeutic agents for glioblastoma
  • 2023 - 2026 GGCT阻害によるNotch制御機構の解明と膠芽腫幹細胞を標的する新規治療法の確立
  • 2022 - 2025 GGCTとxCTのダブル阻害によりフェロトーシスを増強する全く新しいがん治療戦略
  • 2021 - 2024 バイオインフォマティクス的手法による放射線脳壊死関連M2マクロファージの機能解析
  • 2020 - 2023 GGCTによる代謝変容が誘導する新規Hedgehog経路活性化機構の解明
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Papers (61)：
  • Keiichi Ishihara, Ryuto Sakoda, Masako Mizoguchi, Mitsugu Fujita, Chiami Moyama, Yuri Okutani, Kazuyuki Takata, Miwa Tanaka, Takashi Minami, Haruhiko Sago, et al. Suppression of Sleeping Beauty-induced Gliomagenicity in Ts1Cje Mice, a Model of Down Syndrome. Anticancer research. 2024. 44. 2. 489-495
  • Yumiko Saito, Keiko Taniguchi, Hiromi Ii, Mano Horinaka, Susumu Kageyama, Susumu Nakata, Osamu Ukimura, Toshiyuki Sakai. Identification of c-Met as a novel target of γ-glutamylcyclotransferase. Scientific reports. 2023. 13. 1. 11922-11922
  • Yukie Nohara, Keiko Taniguchi, Hiromi Ii, Shun Masuda, Hiroko Kawakami, Masakatsu Matsumoto, Yasunao Hattori, Susumu Kageyama, Toshiyuki Sakai, Susumu Nakata, et al. Development of an activity-based chemiluminogenic probe for γ-glutamylcyclotransferase. Organic & biomolecular chemistry. 2023
  • Kaito Ohta, Hiromi Ii, Chiami Moyama, Shota Ando, Hisanori Nambu, Susumu Nakata, Naoto Kojima. Thiophene Carboxamide Analogs with Long Alkyl Chains Comprising Ethylene Glycol Units Inhibit Glioblastoma Cell Proliferation by Activating AMPK. Journal of Medicinal Chemistry. 2023
  • Chiami Moyama, Mitsugu Fujita, Hitoshi Okamoto, Hiromi Li, Susumu Nakata. Myb Repression Mediates Stat5b-knockdown-induced Apoptosis and Inhibits Proliferation of Glioblastoma Stem Cells. Cancer genomics & proteomics. 2023. 20. 2. 195-202
ｍore...
MISC (144)：
  • 齋藤 友充子, 谷口 恵香, 飯居 宏美, 堀中 真野, 影山 進, 中田 晋, 浮村 理, 酒井 敏行. c-Met発現低下を介したγ-glutamylcyclotrasnferase(GGCT)阻害による前立腺がん細胞増殖抑制の新規分子機構の解明(Identification of c-Met as a novel target of gamma-glutamylcyclotrasnferase in a prostate cancer cell line). 日本泌尿器科学会総会. 2023. 110回. AOP09-07
  • 飯居宏美, 近藤真帆, 伊藤公成, 中田晋. Suppression of Wnt pathway is involved in anticancer activity of GGCT knockdown in colorectal cancer cells. 日本癌学会学術総会抄録集(Web). 2023. 82nd
  • 中田晋, 小島直人. Novel AMPK activators inhibiting mitochondrial complex I that attack glioblastoma, and colon/lung cancer. 日本癌学会学術総会抄録集(Web). 2023. 82nd
  • 山本夏菜, 山向千晶, 松下眞子, 橋本彩花, 野瀬梢, 茂山千愛美, 藤田貢, 飯居宏美, 中田晋. The regulation of GGCT and hedgehog ligands expression in a glioblastoma stem cell model induced by sh-TP53, EGFRvIII and NRasG12V. 日本薬学会年会要旨集(Web). 2023. 143rd
  • 野瀬梢, 森昌也, 茂山千愛美, 飯居宏美, 藤田貢, 中田晋. γ-glutamylcyclotransferase knockdown inhibits proliferation of glioblastoma stem cells. 日本癌学会学術総会抄録集(Web). 2023. 82nd
ｍore...
Patents (2)：
  • NOVEL AMP-ACTIVATED PROTEIN KINASE ACTIVATOR
  • Novel AMPK activators
Books (1)：
  • LGR5 as a marker in brain cancer, Biomarkers in Disease: Methods, Discoveries and Applications
    Springer Netherlands 2015
Education (2)：
  • 2002 - 2006 Kyoto Prefectural University of Medicine Ph D program Medical Science
  • 1992 - 1998 Kyoto Prefectural University of Medicine
Professional career (1)：
  • 博士(医学) (京都府立医科大学)
Work history (8)：
  • 2015/01 - 現在 Kyoto Pharmaceutical University Department of Clinical Oncology Associate Professor
  • 2011/04 - 2014/12 Aichi Cancer Center Research Institute Oncological Pathology Senior Researcher
  • 2010/05 - 2011/03 Yokohama City University Regenerative Medicine Contracted Assistant
  • 2007/11 - 2010/04 German Cancer Research Center Division of Molecular Genetics Guest Scientist
  • 2007/04 - 2007/10 Second Okamoto General Hospital Gastrointestinal Divisions Medical Doctor
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Awards (1)：
  • 2007/11 - Alexander von Humboldt Foundation Fellowship
Association Membership(s) (7)：
日本がん分子標的治療学会 ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  THE JAPANESE SOCIETY OF INTERNAL MEDICINE ,  THE JAPANESE SOCIETY FOR HYGIENE ,  JAPAN GASTROENTEROLOGICAL ENDOSCOPY SOCIETY ,  The Japanese Society of Gastroenterology ,  THE JAPANESE CANCER ASSOCIATION
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