Research theme for competitive and other funds (55)：
2021 - 2023 Paradigm shift in mutation research brought by next generation sequencing: from specific locus test to whole genome analysis
2021 - 2023 Analysis of radiation effects based on high-sensitive detection of mutations in mice and cells exposed to protracted low-dose-rate irradiation.
2017 - 2022 Development of comprehensive identification of spontaneous mutations based on whole genome sequencing applicable for the assessment of low-dose mutagens.
2018 - 2020 The mechanisms of selection of the translation initiation codon; analysis of illegitimate translation in mutant mice created by genome editing
2000 - 2018 Construction of large-scale integrated knowledge database with simulation and data-mining through high-speed network system
2000 - 2018 Gene-driven mutagenesis to construct model mice for human genetic diseases from point-mutation mouse library.
1999 - 2018 Information Biology to elucidate biological function bridging genetics and informatics
2013 - 2016 Elucidation of regulatory mechanisms of GLI transcription factors in Hh signaling using mouse point mutations in Sufu
2013 - 2016 Detection of mouse germline mutations by ultra-throughput genomic analyses and development of the risk assessment system for low-dose mutagens
2009 - 2012 High-throughput development of disease model mice by using next-generation technologies.
2006 - 2007 Genetic analyses of Highly conserved Conserved noncoding sequences in vertebrates
1993 - 1995 Studies on brain functions by gene replacement method.
1993 - 1995 Establishment of DNA repair-deficient or-superproficient mice and their development and molecular basis of genetic instability
1994 - 1994 単一遺伝子病の分子・細胞生物学的研究
1993 - 1994 GENE CONVERSION ASSOCIATED WITH HOMOLOGOUS RECOMBINATION AND DNA REPAIR OF THE MOUSE.
1993 - 1993 導入遺伝子に基づく個体発がんの研究
1993 - 1993 相同組換え遺伝子導入による発癌機構の研究
1993 - 1993 標的遺伝子組換えにみられるジーンコンバージョンの解析
1991 - 1993 相同組換え遺伝子導入による発癌機構の研究
1989 - 1991 導入オンコジ-ンの体細胞突然変異によって起こる個体発癌の研究
ゲノム配列と生物情報を繋ぐ情報処理DB の開発
高速大規模分子生物学/ゲノム解析システム開発
高速大規模発生工学システム構築
新規変異(SNP)発見システム開発
点突然変異生物個体ライブラリー構築
ゲノム創薬/遺伝子機能モデル動物
高速高精度ゲノム配列解析/QTL マッピング
バイオメトリックス/バイオイメージング
データベース情報処理
育種/ミュータジェネシス
Development of information biology bridging DNA sequences and biological functions
Developlent of large-scale high-throughput molecular biological system/genome analysis system
Constraction of high throughput embryonic engineering
Development of novel mutation (SNP) discovery system
Construction of point-mutation mouse library
Genome medicine/model animal for gene function analysis
High throughput genome sequencing/QTL mapping
Biometrics/bioimaging
Database analysis
Inbreeding/mutagenesis
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Papers (105)：
Kaito Harada, Takashi Yahata, Makoto Onizuka, Takamasa Ishii, Abd Aziz Ibrahim, Eri Kikkawa, Yoichi Gondo, Kiyoshi Ando. Mitochondrial Electron Transport Chain Complex II Dysfunction Causes Premature Aging of Hematopoietic Stem Cells. Stem cells (Dayton, Ohio). 2023. 41. 1. 39-49
Yoichi Gondo. DETECTION OF TRANSGENERATIONAL GENETIC EFFECTS BASED ON WHOLE-GENOME SEQUENCING IN THE MOUSE MODEL. Radiation Protection Dosimetry. 2022. 198. 13-15. 1137-1142
Arikuni Uchimura, Hirotaka Matsumoto, Yasunari Satoh, Yohei Minakuchi, Sayaka Wakayama, Teruhiko Wakayama, Mayumi Higuchi, Masakazu Hashimoto, Ryutaro Fukumura, Atsushi Toyoda, et al. Early embryonic mutations reveal dynamics of somatic and germ cell lineages in mice. Genome research. 2022. 32. 5. 945-955
Daiki Hashimoto, Kota Fujimoto, Shin Morioka, Shinya Ayabe, Tomoya Kataoka, Ryutaro Fukumura, Yuko Ueda, Mizuki Kajimoto, Taiju Hyuga, Kentaro Suzuki, et al. Establishment of mouse line showing inducible priapism-like phenotypes. Reproductive Medicine and Biology. 2022. 21. 1. e12472.1-e12472.11
Bohu Pan, Luyao Ren, Vitor Onuchic, Meijian Guan, Rebecca Kusko, Steve Bruinsma, Len Trigg, Andreas Scherer, Baitang Ning, Chaoyang Zhang, et al. Assessing reproducibility of inherited variants detected with short-read whole genome sequencing. Genome Biology. 2022. 23. 1. 2:1-2:26
A Multidisciplinary Challenge to Assess the Next-generation Risks of Low-dose-rate Long-term Gamma-ray Exposure by Whole-genome Sequencing in the Mouse Model
(ICRP2023: 7th International Symposium on the System of Radiation Protection 2023)
High-precision detection of de novo mutations and application to risk assessment for the low-dose-rate longtime exposure to radiation
(The 14th International Workshop on Advanced Genomics (14AGW) 2023)
From Chemical Mutagens to Radiation: “IDENSHI” is quite confusing
(The 95th Annual Meeting of Japanese Society of Genetics 2023)
1980 - 1987 University of Colorado Graduate School, Boulder, USA Department of Molecular, Cellular and Developmental Biology
Professional career (1)：
Ph.D. (University of Colorado, Boulder)
Work history (11)：
2022/08 - 現在 Tokai University Institute of Medical Sciences Research Scientist
2021/04 - 現在 Osaka University Research Center for Nuclear Physics Visiting Scientist
2021/04 - 現在 Tokai University School of Medicine Visiting Professor
2018/01 - 2023/03 RIKEN BioResource Center Visiting Scientist
2018/01 - 2021/03 Tokai University School of Medicine Professor
1999/08 - 2017/12 RIKEN Team Leader
1995/04 - 1999/07 Tokai University Institute of Medical Sciences Associate Professor
1993/04 - 1995/03 Kyushu University Institute of Medical Regulation Assistant Professor
1990/10 - 1993/03 Tokai University School of Medicine Junior Research Associate
1989/07 - 1990/09 Fox Chase Cancer Center, USA Postdoctoral Research Associate
1987/11 - 1989/07 The Jackson Laboratory, USA Postdoctoral Researcher
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Committee career (10)：
2019/10 - 現在 The 195th Committee of Radiation member
2014 - 現在 Genes and Genetic Systems Advisory Board Member
2012 - 現在 MicroArray Quality Control/Sequencing Quality Control Consortium Member
2002 - 現在 Genome Technology Committee Academic Member
2012/06 - 2022/06 Radiation Effects Research Foundation Scientific Advisory Committee
2021 - 2022 Genetics Society of Japan Executive Councilor
2017 - 2018 Genetics Society of Japan Executive Councilor
2015 - 2016 International Mammalian Genome Society Nomination and Election Committee Member
2011 - 2014 Genetics Society of Japan Executive Counsilor
2006 - 2009 International Mammalian Genome Society Secretariat
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Awards (3)：
2012 - X-GENE COngress & EXPO Oxford Nanopore Excellent Poster Award
2010 - Genetics Society of Japan Best Paper Award
2009 - The Organizing Committee of the 8th International Workshop on Advanced Genomics Excellent Poster Award
Association Membership(s) (8)：
International Mammalian Genome Society
, Society of Evolutionary Studies, Japan
, Japanese Society for Bioinformatics
, Japanese Cancer Association
, The Molecular Biology Society of Japan
, The Genetics Society of Japan
, The Genetics Society of America
, Japanese Society of Human Genetics
