Yuan Bo

エンパク | Yuan Bo

Affiliation and department：

Research field (3)： Tumor biology , Clinical pharmacy , Pharmaceuticals - health and biochemistry

Research keywords (9)：薬物トランスポーター , 抗がん剤 , がん , 天然物由来物質 , 薬物併用効果 , 医療系薬学 , 生物系薬学 , Cell Biology , Biopharmaceutics

Research theme for competitive and other funds (9)：

2021 - 2024 Fundamental research of antidepressant-like effect of a novel curcumin derivative CUD003 in mice
2020 - 2023 Fundamental research of antitumor activity of arsenic compound in combination with active bufadienolide compounds against glioblastoma cells
2019 - 2023 Can the FAD012, a ferulic acid derivative, be a new preventive agent for ischemic cerebrovascular disorder?
2020 - 2021 Studies on the antitumor activity of new synthetic analogs of ferulic acid against leukemia cells
2019 - 2020 Fundamental research of antitumor activity of new synthetic analogs of ferulic acid and curcumin

Show all

Papers (79)：

Takashi Asano, Meiyan Xuan, Naohiro Iwata, Jun Takayama, Kousuke Hayashi, Yosuke Kato, Toshiya Aoyama, Hiroshi Sugo, Hirokazu Matsuzaki, Bo Yuan, et al. Involvement of the Restoration of Cerebral Blood Flow and Maintenance of eNOS Expression in the Prophylactic Protective Effect of the Novel Ferulic Acid Derivative FAD012 against Ischemia/Reperfusion Injuries in Rats. International Journal of Molecular Sciences. 2023. 24. 11. 9663-9663
Bo Yuan, Hidetomo Kikuchi, Jingmei Li, Atsushi Kawabata, Kozo Yao, Norio Takagi, Mari Okazaki. Cytotoxic Effects of Darinaparsin, a Novel Organic Arsenical, against Human Leukemia Cells. International Journal of Molecular Sciences. 2023. 24. 3. 2282-2282
Bo Yuan, Jingmei Li, Shin-Ich Miyashita, Hidetomo Kikuchi, Meiyan Xuan, Hirokazu Matsuzaki, Naohiro Iwata, Shinya Kamiuchi, Katsuyoshi Sunaga, Takeshi Sakamoto, et al. Enhanced Cytotoxic Effects of Arenite in Combination with Active Bufadienolide Compounds against Human Glioblastoma Cell Line U-87. Molecules. 2022. 27. 19. 6577-6577
Yoshio Nishimura, Hidetomo Kikuchi, Takanori Kubo, Rie Arai, Yuki Toguchi, Bo Yuan, Katsuyoshi Sunaga, Hidetsura Cho. Synthesis of 4,4-Disubstituted 3,4-Dihydropyrimidin-2(1H)-ones and -thiones, the Corresponding Products of Biginelli Reaction Using Ketone, and Their Antiproliferative Effect on HL-60 Cells. Chemical and Pharmaceutical Bulletin. 2022. 70. 2. 111-119
Hideki Hayashi, Misuzu Mori, Mina Harashima, Tatsuya Hashizume, Miho Furiya, Chihaya Mukaigaito, Emi Takemura, Mariko Yamada, Kanako Mise, Bo Yuan, et al. Apolipoprotein E-Containing Lipoproteins and LRP1 Protect From NMDA-Induced Excitotoxicity Associated With Reducing α2-Macroglobulin in Müller Glia. Investigative Opthalmology & Visual Science. 2021. 62. 13. 23-23

ｍore...

MISC (51)：

渡口由姫, 菊地秀与, 西村良夫, 袁博, 新井理絵, 久保貴紀, 長秀連, 須永克佳. ヒト急性前骨髄球性白血病細胞株NB4に対する2-methylthio dihydropyrimidine誘導体の細胞毒性. 日本薬学会年会要旨集. 2022. 142年会. 26PO5-06S
菊地秀与, 渡口由姫, 西村良夫, 袁博, 新井理絵, 久保貴紀, 長秀連, 須永克佳. ヒト白血病細胞株NB4およびHL-60に対する2-thioxo-dihydropyrimidine誘導体の細胞毒性. 日本薬学会年会要旨集. 2022. 142年会. 26PO5-07
袁博, 菊地秀与, 高木教夫, 岡崎真理. 微量元素研究領域の最前線:生理機能の解明と創薬研究ヒ素化合物の臨床応用および抗腫瘍活性メカニズム. Biomedical Research on Trace Elements. 2021. 32. 2. 60-60
袁博, 高木教夫, 岡崎真理, 平野俊彦. 元素の力で切り拓く次世代の低分子創薬〜重水素から高周期元素までヒ素化合物の抗腫瘍活性およびその新規臨床応用の可能性(Anti-tumor activity of arsenic compounds and its potential novel application in clincs). 日本薬学会年会要旨集. 2021. 141年会. S11-5
菊地秀与, 西村良夫, 久保貴紀, 袁博, 須永克佳, 長秀連. 2-thioxo-dihydropyrimidine誘導体のHL-60細胞の細胞周期に及ぼす影響. 日本薬学会年会要旨集. 2021. 141年会. 28P02-169

ｍore...

Lectures and oral presentations (2)：

微量元素研究領域の最前線:生理機能の解明と創薬研究ヒ素化合物の臨床応用および抗腫瘍活性メカニズム
(Biomedical Research on Trace Elements 2021)
元素の力で切り拓く次世代の低分子創薬〜重水素から高周期元素までヒ素化合物の抗腫瘍活性およびその新規臨床応用の可能性(Anti-tumor activity of arsenic compounds and its potential novel application in clincs)
(日本薬学会年会要旨集 2021)

Education (2)：

1998 - 2000 Tokyo University of Pharmacy and Life Sciences Department of Pharmaceutical Sciences, Graduate School of Pharmacy Pharmacy
1988 - 1993 ShenYang Pharmaceutical University School of Pharmacy Pharmacy

Professional career (1)：

Ph.D.

Work history (7)：

2022/10 - 現在 Josai University Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences Department of Pharmaceutical Professor
2019/04 - 2022/09 School of Pharmacy, Faculty of Pharmacy and Pharmaceutical Sciences, Josai University Laboratory of Pharmacology Associate professor
2013/04 - 2019/03 Tokyo University of Pharmacy and Life Sciences Department of Applied Biochemistry, School of Pharmacy Assistant professor
2009/04 - 2013/03 Tokyo University of Pharmacy and Life Sciences Department of Clinical Molecular Genetics, School of Pharmacy Assistant professor
2009/07 - 2010/08 University of California, San Francisco (UCSF) Department of Bioengineering and Therapeutic Sciences Visiting assistant professor

Show all

Awards (3)：

2012/03 - Tokyo University of Pharmacy and Life Sciences Nakako Yoshida Memorial Award Cytocidal effects of arsenite on human-derived normal and malignant cells, and its pharmacokinetics in APL patients
1999 - Iwaki Scholarship Foundation Scholarship from Iwaki Scholarship Foundation
1998 - Scholarship of Independent Administrative Institution Japan Student Services Organization Scholarships for International Students in Japan

Association Membership(s) (4)：

Specialty Committee of Hematology of World Federation of Chinese Medicine Societies Council Member & Vice Secretary General , THE PHARMACEUTICAL SOCIETY OF JAPAN , THE JAPANESE BIOCHEMICAL SOCIETY , The Japanese Pharmacological Society

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page