Research field (3):
Applied molecular and cellular biology
, Food sciences
, Applied biochemistry
Research keywords (8):
加齢性疾患
, 生活習慣病
, アンチエイジング
, テロメラーゼ
, 老化
, Cancer
, Telomerase
, Senescence
Research theme for competitive and other funds (26):
2021 - 2024 Molecular basis for the activation of exosome-mediated gut-brain interaction by food
2016 - 2019 Molecular basis for the exosome-mediated food function
2014 - 2018 Construction of the libraries and the database including health functions in Nepalese wild mushrooms
2012 - 2016 Screening for anti-aging food that regulates intestinal function and clarification of its molecular basis
2012 - 2015 Nicotinamide potentiates HDAC inhibitor-induced cytotoxicity in human breast cancer cells through DNA damage accumulation
2007 - 2008 Analysis of molecular basis for aging regulated by cellular senescence programs and its application to development of anti-aging drugs
2005 - 2006 Molecular basis for senescence and aging, and its application for anti-aging medicine.
2006 - 腸内細菌の有する生理活性に関する研究
2003 - 2004 Identification of factors inducing cellular senescence and possible application them to drug design
2002 - 2004 Development of tecnologies for production of high affinity human antibodies and its application to specific therapies and risk evaluation.
2000 - 2001 ガン細胞の有限寿命化に向けた多面的アプローチ
1999 - 2000 活性酸素消去能をもつ還元水による糖尿病の抑制
1996 - 1996 不死化細胞株におけるテロメラーゼ活性発現機構の解析
1996 - ヒトモノクローナル抗体作製技術の開発
1996 - 動物細胞による組換えタンパク質高発現系の開発
1996 - 細胞老化制御因子に関する研究
1996 - 動物細胞におけるテロメラーゼ制御機構に関する研究
1996 - Establishment of production system of human monoclonal antibody
1996 - Establishment of highly efficient expression system of recombinant proteins in mammalian cells
1996 - Study on cellular senescence regulatory factor
1996 - Telomerase regulation in mammalian cells
1995 - 1995 ヒトリンパ球系細胞からの新規インターフェロン様タンパク質の単離と同定
生活習慣病治療・予防のための新規創薬ターゲットとしての老化制御因子の同定及び機能解析
テロメラーゼプロモーターを用いた新規抗ガン治療法の開発
Novel anticancer therapy using human TERT promoter
Repression mechanisms of telomerase
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Papers (223):
Takeki Hamasaki, Kiichro Teruya, Yoshinori Katakura. Effect of Hita Tenryo WaterTM, a natural mineral water, on allergic symptoms induced by cedar in mice. Heliyon. 2024. 10. 5. e26915
Sonam Tamrakar, Dongmei Wang, Eri Hiraki, Chunguang Han, Yang Ruan, Ahmed E Allam, Yhiya Amen, Yoshinori Katakura, Kuniyoshi Shimizu. Deacylated Derivative of Hericenone C Treated by Lipase Shows Enhanced Neuroprotective Properties Compared to Its Parent Compound. Molecules (Basel, Switzerland). 2023. 28. 11
Asuka Ishibashi, Miyako Udono, Mikako Sato, Yoshinori Katakura. Molecular Mechanisms for the Carnosine-Induced Activation of Muscle-Brain Interaction. Nutrients. 2023. 15. 6
Akane Mihara, Tomoyuki Ohara, Jun Hata, Sanmei Chen, Takanori Honda, Sonam Tamrakar, Akiko Isa, Dongmei Wang, Kuniyoshi Shimizu, Yoshinori Katakura, et al. Association of serum s-adenosylmethionine, s-adenosylhomocysteine, and their ratio with the risk of dementia and death in a community. Scientific reports. 2022. 12. 1. 12427-12427
Tsukasa Fujiki, Ryosuke Shinozaki, Miyako Udono, Yoshinori Katakura. Identification and Functional Evaluation of Polyphenols That Induce Regulatory T Cells. Nutrients. 2022. 14. 14
Jun Hata, Tomoyuki Ohara, Yoshinori Katakura, Kuniyoshi Shimizu, Shuntaro Yamashita, Daigo Yoshida, Takanori Honda, Yoichiro Hirakawa, Mao Shibata, Satoko Sakata, et al. Association Between Serum β-Alanine and Risk of Dementia. American journal of epidemiology. 2019. 188. 9. 1637-1645
日本食品免疫学会
, 日本分子生物学会
, 日本免疫学会
, 日本動物細胞工学会
, 日本農芸化学会
, Japanese Association for Animal Cell Technology
, The Molecular Biology Society of Japan
, Japanese Society for Immunology
, and Agrochemistry
, Biotechnology
, Japan Society for Bioscience