Rchr
J-GLOBAL ID：200901028128659390   Update date: Apr. 22, 2023

Kanamori Akiko

カナモリ アキコ | Kanamori Akiko
Affiliation and department：
東海大学 工学部生命化学科

About 東海大学 工学部生命化学科


Job title： 教授
Research field  (2)： Functional biochemistry ,  Structural biochemistry
Research keywords  (14)： γーグルタミルトランスペプチダーゼ(γ-GTP) ,  glutathione ,  糖化ストレス ,  酸化ストレス ,  抗酸化作用 ,  転移 ,  細胞接着 ,  シアル酸 ,  糖鎖 ,  Metastasis ,  Tumor ,  Cell adhesion ,  Sialic acid ,  Glycoconjugate
Research theme for competitive and other funds  (18)：
  • 2022 - 2023 チオールとセレノールの反応性を活用した酸化ストレス関連疾病の新規治療薬の開発
  • 2016 - 2022 セレン含有化合物の抗酸化力を活用した酸化ストレス関連疾病の新規治療薬の開発
  • 2015 - 2018 セレンの反応性を利用した病原性タンパク質の化学的・生化学的手法による制御
  • 2013 - 2015 Application of selenocysteine for enhancement of the reactivity of the enzymes related on redox regulation system
  • 2005 - 2006 Mechanisms involved in the induction of cell adhesion by hypoxia inducible factor
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Papers (46)：
  • AKIKO KANAMORI. Analysis of the effect of monosaccharide modified glutathione derivative on the concentration reduction of contact dermatitis causative agents. Bulletin of the Institute of Advanced Biosciences. 2023. 7. 11-14
  • Akiko Kanamori. Design and application of a glutathione derivative which has resistance against degradation by gamma-glutamyltranspeptidase. Bulletin of the Institute of Advanced Biosciences. 2022. 6. 6-9
  • Akiko Kanamori. Addition of selenoglutathione to culture medium of the cells where the expression level of glyoxalase 1 is suppressed can restore the resistance to both glycation and oxidative stress. Bulletin of the Institute of Advanced Biosciences. 2021. 5. 5-8
  • Kenta Arai, Yuumi Sato, Ikumi Nakajima, Manami Saito, Moeka Sasaki, Akiko Kanamori, Michio Iwaoka. Glutathione peroxidase-like functions of 1,2-diselenane-4,5-diol and its amphiphilic derivatives: Switchable catalytic cycles depending on peroxide substrates. Bioorganic & medicinal chemistry. 2021. 29. 115866-115866
  • Akiko Kanamori. Enhancement of cellular resistance to both oxidative and glycation stress by incorporation of selenoglutathione. Bulletin of the Institute of Advanced Biosciences. 2020. 4. 5-8
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MISC (38)：
  • Analysis and application of a glycosylated glutathione derivative which has resistance against degradation by gamma-glutamyltranspeptidase. 日本糖質学会年会要旨集. 2022. 41st. 205
  • 坪井亮, 熊坂実優, 金森審子, 横山奨, 木村啓志, 岡村陽介. 眼病予防薬剤を内包した高分子超薄膜の調製と機能評価. 日本バイオマテリアル学会大会予稿集(Web). 2018. 40th
  • 和泉雅之, DEDOLA Simone, 木内達人, 來間利江, 牧村裕, 瀬古玲, 金森審子, 迫野昌文, 伊藤幸成, 梶原康宏. ハイマンノース型糖鎖を有する糖タンパク質の精密化学合成とそれを利用したフォールディングセンサー酵素UGGTの基質認識機構の解明. 天然有機化合物討論会講演要旨集(Web). 2013. 55th
  • 和泉雅之, DEDOLA Simone, 牧村裕, 瀬古玲, 金森審子, 伊藤幸成, 梶原康宏. フォールディングセンサーUGGTの基質認識に重要な変性糖タンパク質の構造. 日本化学会講演予稿集. 2012. 92nd. 3
  • 伊藤 幸成, 金森 審子, 瀬古 玲. 化学合成をツールとする糖タンパク質の小胞体内機能解析-Functional analysis of glycoprotein biosynthesis in the ER through strategy of synthetic chemistry-特集 次世代ケミカルバイオロジーの新展開. 化學工業. 2011. 62. 2. 153-160
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Books (1)：
  • Cyclic sialic acid: a new regulatory mechanism of selectin ligand activity,In: Y. Inoue, Y. C. Lee and F. A. Troy (eds.), Sialobiology and Other Novel Formsof Glycosylation, 37-43
    Osaka, Japan: Gakushin Publisher 1999
Lectures and oral presentations  (58)：
  • Analysis of reactivity of a glycosylated glutathione derivative with chemicals causing contact dermatitis
    (2022)
  • Analysis of reactivity of a glycosylated glutathione derivative, which is not degraded by gamma-glutamyltranspeptidase, with chemicals causing contact dermatitis
    (2022)
  • Regulating of redox balance in cells by using a water-soluble cyclic diselenide and its amphiphilic derivatives with glutathione peroxidase-like activity
    (The 95th Annual Meeting of the Japanese Biochemical Society 2022)
  • Analysis and application of a glycosylated glutathione derivative which has resistance against degradation by gamma-glutamyltranspeptidase
    (日本糖質学会年会要旨集 2022)
  • Addition of selenoglutathione to culture medium of the cells where the expression level of glyoxalase 1 is suppressed can restore the resistance to both glycation and oxidative stress
    (日本分子生物学会年会プログラム・要旨集(Web) 2021)
ｍore...
Professional career (1)：
  • 理学博士 (東京大学)
Work history (7)：
  • 2022/04 - 現在 Tokai University School of Engineering professor
  • 2013/04 - 現在 Tokai University School of Engineering
  • 2010/04 - 2013/03 (独)科学技術振興機構 ERATO・伊藤グライコトリロジー(伊藤幸成研究総括) プロジェクト研究員
  • 2005/04 - 2010/03 Aichi Cancer Center, Research Institute
  • 1998/04 - 2005/03 Aichi Cancer Center, Research Institute
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Committee career (3)：
  • 2022/09 - 現在 The Japanese Biochemical Society Honorary Member
  • GlycoTokyo 幹事会員
  • 日本糖質学会 評議員
Association Membership(s) (6)：
日本メイラード学会 ,  日本免疫学会 ,  日本分子生物学会 ,  日本糖質学会 ,  日本生化学会 ,  日本癌学会
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