Rchr
J-GLOBAL ID：200901028204742677   Update date: Jan. 31, 2024

Takaoka Akinori

タカオカ アキノリ | Takaoka Akinori
Affiliation and department：
Hokkaido University Institute for Genetic Medicine, Research Section of Molecular Pathogenesis

About Hokkaido University Institute for Genetic Medicine, Research Section of Molecular Pathogenesis


Job title： Professor
Homepage URL  (1)： http://www.igm.hokudai.ac.jp/sci/
Research field  (2)： Immunology ,  Medical biochemistry
Research theme for competitive and other funds  (21)：
  • 2022 - 2027 Intrinsic immunityに着目した新しい抗ウイルス防御機構の探索
  • 2018 - 2021 Research on the immune system in uninfected cells that defines the immune response during viral infection
  • 2017 - 2020 The molecular mechanism of cancer specific cell death induction via novel innate immune signaling
  • 2013 - 2018 The novel post-transcriptional regulation mechanism of antiviral host defense
  • 2014 - 2017 Activation of innate immune response by DNA from food
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Papers (76)：
  • Nabeel Kajihara, Yoshino Tanaka, Riko Takeuchi, Takuto Kobayashi, Masafumi Tanji, Tsukasa Ataka, Shiho Nakano, Taisho Yamada, Akinori Takaoka, Yoshinori Hasegawa, et al. Augmented interferon regulatory factor 7 axis in whole tumor cell vaccines prevents tumor recurrence by inducing interferon gamma-secreting B cells. OncoImmunology. 2023. 12. 1
  • Taisho Yamada, Akinori Takaoka. Innate immune recognition against SARS-CoV-2. Inflammation and Regeneration. 2023. 43. 1
  • Akhilesh Kumar, Shalabh Mishra, Ashish Kumar, Ashwin Ashok Raut, Seiichi Sato, Akinori Takaoka, Himanshu Kumar. Essential role of Rnd1 in innate immunity during viral and bacterial infections. Cell death & disease. 2022. 13. 6. 520-520
  • Shin Hashizume, Masako Nakano, Kenta Kubota, Seiichi Sato, Nobuaki Himuro, Eiji Kobayashi, Akinori Takaoka, Mineko Fujimiya. Mindfulness intervention improves cognitive function in older adults by enhancing the level of miRNA-29c in neuron-derived extracellular vesicles. Scientific Reports. 2021. 11. 1. 21848-21848
  • Sunanda Baidya, Yoko Nishimoto, Seiichi Sato, Yasuhiro Shimada, Nozomi Sakurai, Hirotaka Nonaka, Koki Noguchi, Mizuki Kido, Satoshi Tadano, Kozo Ishikawa, et al. Dual Effect of Organogermanium Compound THGP on RIG-I-Mediated Viral Sensing and Viral Replication during Influenza a Virus Infection. Viruses. 2021. 13. 9. 1674-1674
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MISC (43)：
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Lectures and oral presentations  (8)：
  • Direct and indirect roles of RIG-I for antiviral defense against hepatitis B virus in human hepatocytes
    (International Conference on Antimicrobial Research 2014)
  • Role of the cytoplasmic RNA sensor RIG-I in innate immune defense against hepatitis B virus infection
    (11th International Conference on Innate Immunity 2014)
  • ZAPS acts as a key factor of RIG-I-mediated activation of innate immune responses during influenza virus
    (2nd International Conference on Clinical & Cellular Immunology 2013)
  • Innate immune signaling networks during host-microbe interaction
    (CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences 2013)
  • Nucleic acid sensors for detecting viral infection
    (IEIIS2012 Homeostatic Inflammation Symposium 2012)
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Education (4)：
  • - 1996 Sapporo Medical University Graduate School of Medicine
  • - 1996 Sapporo Medical University Graduate School, Division of Medicine
  • - 1992 Sapporo Medical University School of Medicine
  • - 1992 Sapporo Medical University Faculty of Medicine
Professional career (1)：
  • 博士(医学) (札幌医科大学)
Work history (13)：
  • 2017/10 - 現在 Hokkaido University Institute for Genetic Medicine
  • 2007/05 - 現在 Hokkaido University Institute for Genetic Medicine
  • 2012/04 - 2016/03 Hokkaido University Institute for Genetic Medicine
  • 2009/07 - 2012/03 Hokkaido University Institute for Genetic Medicine
  • 2002 - 2007 東京大学医学部免疫学講座 講師
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Committee career (5)：
  • 2014/04 - 現在 日本がん免疫学会 理事
  • 2014/01 - 現在 日本癌学会 評議員
  • 2013/06 - 現在 秋山記念生命科学振興財団 評議員
  • 2013/04 - 2015/03 北海道医学会 評議員
  • 2007 - 日本免疫学会 評議員
Awards (9)：
  • 2015/03 - 北海道大学 研究総長賞(優秀賞)
  • 2014/03 - 北海道大学 教育総長賞
  • 2013/03 - 北海道大学 研究総長賞
  • 2011 - 医学研究奨励賞 (日本医師会:日本)
  • 2005 - 三菱化学奨励賞 (分子生物学会:日本)
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Association Membership(s) (11)：
日本ウイルス学会 ,  日本免疫学会 ,  International Society for Interferon and Cytokine Research ,  International Cytokine Society ,  日本分子生物学会 ,  日本癌学会 ,  北海道医学会 ,  北海道癌談話会 ,  日本生化学会 ,  がん分子標的治研究会 ,  日本インターフェロン・サイトカイン学会
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