Rchr
J-GLOBAL ID：200901028736433290
Update date: Apr. 12, 2024
NEMOTO-SASAKI Yoko
ササキ ヨウコ | NEMOTO-SASAKI Yoko
Affiliation and department：
Job title：
Lecturer
Homepage URL (1)：
https://www.teikyo-u.ac.jp/faculties/pharmacy_d/labo
Research field (4)：
Digestive surgery
, Tumor biology
, Pharmaceuticals - health and biochemistry
, Functional biochemistry
Research keywords (11)：
tumor metastasis
, がん
, リン脂質
, C. elegans
, レクチン
, 複合糖質
, tumor
, phospholipids
, C.elegans
, lectins
, glycoconjugates
Research theme for competitive and other funds (5)：
- 2020 - 2025 Regulation of colorectal cancer metastasis by fatty acid remodeling enzymes involved in glycerophospholipid metabolism
- 2019 - 2022 Cancelation of Warburg effect and anti cancer effect of pancreatic cancer cells by intracellular phospholipase A1.
- 2015 - 2018 Novel functions and relevance to the diseases of intracellular phospholipase A1
- 2012 - 2015 Research for the novel metabolic routes of endogenous marijuana-like substance, lysophosphatidylinosiol.
- 2002 - 2002 がん細胞選択的発現ベクターによる、ケモカイン遺伝子治療法の基礎的検討
Papers (26)：
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Keisuke Nakajima, Saori Oka, Takashi Tanikawa, Yoko Nemoto-Sasaki, Naoki Matsumoto, Hiroki Ishiguro, Yoichiro Arata, Takayuki Sugiura, Atsushi Yamashita. Lysophosphatidylinositol Induced Morphological Changes and Stress Fiber Formation through the GPR55-RhoA-ROCK Pathway. International journal of molecular sciences. 2022. 23. 18
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Takashi Tanikawa, Saori Oka, Keisuke Nakajima, Yasuhiro Hayashi, Yoko Nemoto-Sasaki, Yoichiro Arata, Takayuki Sugiura, Atsushi Yamashita. Expression and Distribution of GPR55, a Receptor for Lysophosphatidylinositol, in Mouse Tissues and Cells. BPB Reports. 2022. 5. 2. 16-20
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Yasuhiro Hayashi, Kiyoto Tsuchiya, Mizuki Yamamoto, Yoko Nemoto-Sasaki, Kazunari Tanigawa, Kotaro Hama, Yusuke Ueda, Takashi Tanikawa, Jin Gohda, Kenji Maeda, et al. N-(4-Hydroxyphenyl) retinamide suppresses SARS-CoV-2 spike protein-mediated cell-cell fusion by a dihydroceramide Δ4-desaturase 1-independent mechanism. Journal of virology. 2021. 95. 17. JVI0080721
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Naoki Matsumoto, Yoko Nemoto-Sasaki, Saori Oka, Seisuke Arai, Ikuo Wada, Atsushi Yamashita. Phosphorylation of human phospholipase A1 DDHD1 at newly identified phosphosites affects its subcellular localization. The Journal of biological chemistry. 2021. 100851-100851
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Yoko Nemoto-Sasaki, Tatsuro Irimura, Atsushi Yamashita. Gene expression analysis of lysophospholipid acyltransferases in mouse metastatic variant cell lines. 日本癌学会総会記事. 2019. 78回. P-1090
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MISC (10)：
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佐々木 洋子, 林 康広, 松本 直樹, 小泉 昂範, 橋本 貴史, 河合 宥佳, 山内 眞優, 前原 美那, 入村 達郎, 山下 純. マウスメラノーマおよび大腸がん細胞株におけるリゾリン脂質アシルトランスフェラーゼ発現量の比較. 日本生化学会大会プログラム・講演要旨集. 2019. 92回. [2P-032]
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山下 純, 古賀 裕基, 鈴木 尚孝, 林 康広, 佐々木 洋子, 岡 沙織, 谷川 尚, 杉浦 隆之. アシルグリセロリン酸アシルトランスフェラーゼ8(AGPAT8)の基質特異性とトランスアシレーション反応. 脂質生化学研究. 2012. 54. 152-154
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山下 純, 鈴木 尚孝, 古賀 裕基, 佐々木 洋子, 林 康広, 岡 沙織, 杉浦 隆之. 膜結合アシルトランスフェラーゼによるCoA依存性トランスアシレーション反応. 脂質生化学研究. 2011. 53. 48-51
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Tomita Y., Yang X., Kitakata H., Popivanova B.K., Nemoto-Sasaki Y., Mukaida Naofumi. Essential contribution of tumor necrosis factor receptor (TNF-R) p55-mediated signals in metastasis and carcinogenesis. Cancer Research Institute report. 2006. 2003. 26-26
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Kitakata H., Nemoto-Sasaki Y., Takahashi Yutaka, Mai M., Mukaida Naofumi. Essential roles of tumor necrosis factor receptor p55 in liver metastasis of intrasplenic administration of colon 26 cells. Cancer Research Institute report. 2003. 2000. 102-102
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Books (3)：
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パザパ薬学演習シリーズ13 生化学演習 第2版
京都廣川書店 2022
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パザパ薬学演習シリーズ13 生化学演習
京都廣川書店 2013
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The Molecular Immunology of Complex Carbohydrates 2, Advances in Experimental Medicine and Biology, vol. 491
Kluwer Academic/Plenum Publishers 2001
Lectures and oral presentations (49)：
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Phosphatidylcholine and phosphatidylethanolamine contents in colorectal cancer cell lines with different liver metastatic potential.
(2024)
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Comparison of phosphatidylcholine and phosphatidylethanolamine contents in mouse colon cancer metastatic variant cells
(2023)
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細胞内型ホスホリパーゼA1の酵素活性に対する二価金属イオンの反応性の相違と相互作用の解析
(日本薬学会第143年会 2023)
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The expressions of lysophosphatidylcholine acyltransferases (LPCATs) in highly liver-metastatic variant and parental cell lines of colon carcinoma.
(2022)
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ヒト細胞内型ホスホリパーゼA1のリン酸化は細胞内局在の制御に関わる
(第95回日本生化学会大会 2022)
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Education (4)：
- 1997 - 2000 The University of Tokyo
- 1995 - 1997 The University of Tokyo Graduate School, Division of Pharmaceutical Sciences
- 1993 - 1995 The University of Tokyo Faculty of Pharmaceutical Sciences Department of Pharmacy
- 1991 - 1993 The University of Tokyo
Professional career (2)：
- PhD (The University of Tokyo)
- Master (The University of Tokyo)
Work history (4)：
- 2012/04 - 現在 Teikyo University Lecturer
- 2007/04 - 2012/03 Teikyo University Assistant Professor
- 2003/04 - 2007/03 Teikyo University Research Associate
- 2000/04 - 2003/03 Cancer Research Institute, Kanazawa University Research Associate
Awards (1)：
- 2011/09 - The Naito Foundation The Naito Conference Poster Award Characterization of the galectin family genes of Caenorhabditis elegans: Carbohydrate-binding properties and phenotypes of mutant worms under stress conditions
Association Membership(s) (6)：
THE JAPANESE CONFERENCE ON THE BIOCHEMISRTY OF LIPIDS
, 日本薬学会
, 日本分子生物学会
, 日本生化学会
, 日本癌学会
, 日本糖質学会
