Rchr
J-GLOBAL ID：200901028785668120
Update date: Jan. 17, 2024
ADACHI TAKAHIRO
アダチ タカヒロ | ADACHI TAKAHIRO
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Research field (6)：
Applied biochemistry
, Conservation science (plants)
, Molecular biology
, Functional biochemistry
, Applied biofunctional and bioprocess engineering
, Polymer materials
Research keywords (10)：
タンパク質生産
, 血球
, 基底膜
, ゼラチン
, コラーゲン
, 遺伝子組換え
, カイコ
, molecular biology
, biochemistry
, biotechnology
Research theme for competitive and other funds (6)：
2007 - 2010 ヒト型ゼラチンを合成する遺伝子組換えカイコの作出
1998 - 2010 遺伝子組み換えカイコを利用したタンパク質生産
1998 - 2009 Synthesis of human collagen in silkworms, Bombyx mori
1998 - 2006 カイコ血球において合成されるIV型コラーゲンに関する研究
1995 - 1997 海産生物ホヤにおけるバナジウム濃縮に関連する研究
Involvement of type IV collagen in self-defense reaction and metamorphosis in insects
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Papers (9)：
Takashi Kitajima, Sei Obuse, Takahiro Adachi, Masahiro Tomita, Yoshihiro Ito. Recombinant Human Gelatin Substitute With Photoreactive Properties for Cell Culture and Tissue Engineering. BIOTECHNOLOGY AND BIOENGINEERING. 2011. 108. 10. 2468-2476
Shinya Urano, Chinatsu Kaneko, Takahito Nei, Natsuki Motoi, Ryushi Tazawa, Masato Watanabe, Masahiro Tomita, Takahiro Adachi, Hiroko Kanazawa, Koh Nakata. A cell-free assay to estimate the neutralizing capacity of granulocyte-macrophage colony-stimulating factor autoantibodies. JOURNAL OF IMMUNOLOGICAL METHODS. 2010. 360. 1-2. 141-148
Takahiro Adachi, Xiaobiao Wang, Tomoko Murata, Masanobu Obara, Hidenori Akutsu, Masakazu Machida, Akirihiro Umezawa, Masahiro Tomita. Production of a Non-Triple Helical Collagen alpha Chain in Transgenic Silkworms and Its Evaluation as a Gelatin Substitute for Cell Culture. BIOTECHNOLOGY AND BIOENGINEERING. 2010. 106. 6. 860-870
Masahiro Tomita, Rika Hino, Shingo Ogawa, Masashi Iizuka, Takahiro Adachi, Katsuhiko Shimizu, Hisaya Sotoshiro, Katsutoshi Yoshizato. A germline transgenic silkworm that secretes recombinant proteins in the sericin layer of cocoon. TRANSGENIC RESEARCH. 2007. 16. 4. 449-465
Katsuhiko Shimizu, Shingo Ogawa, Rika Hino, Takahiro Adachi, Masahiro Tomita, Katsutoshi Yoshizato. Structure and function of 5 '-flanking regions of Bombyx mori fibroin heavy chain gene: Identification of a novel transcription enhancing element with a homeodomain protein-binding motif. INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2007. 37. 7. 713-725
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MISC (6)：
Katsuhiko Shimizu, Shingo Ogawa, Rika Hino, Takahiro Adachi, Masahiro Tomita, Katsutoshi Yoshizato. Structure and function of 5 '-flanking regions of Bombyx mori fibroin heavy chain gene: Identification of a novel transcription enhancing element with a homeodomain protein-binding motif. INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2007. 37. 7. 713-725
Tomita M, Hino R, Ogawa S, Iizuka M, Adachi T, Shimizu K, Sotoshiro H, Yoshizato K. A germline transgenic silkworm that secretes recombinant proteins in the sericin layer of cocoon. Transgenic Res. 2007, 16, 449-65. Transgenic Res. 2007. 16. 449-65.
Takahiro Adachi, Masahiro Tomita, Katsuhiko Shimizu, Shingo Ogawa, Katsutoshi Yoshizato. Generation of hybrid transgenic silkworms that express Bombyx mori prolyl-hydroxylase alpha-subunits and human collagens in posterior silk glands: Production of cocoons that contained collagens with hydroxylated proline residues. JOURNAL OF BIOTECHNOLOGY. 2006. 126. 2. 205-219
T Adachi, M Tomita, K Yoshizato. Synthesis of prolyl 4-hydroxylase ot subunit and type IV collagen in hemocytic granular cells of silkworm, Bombyx mori: Involvement of type IV collagen in self-defense reaction and metamorphosis. MATRIX BIOLOGY. 2005. 24. 2. 136-154
T Ueki, T Adachi, S Kawano, M Aoshima, N Yamaguchi, K Kanamori, H Michibata. Vanadium-binding proteins (vanabins) from a vanadium-rich ascidian Ascidia sydneiensis samea. BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION. 2003. 1626. 1-3. 43-50
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Patents (1)：
ヒト・コラーゲンを産生する形質転換カイコ
Books (1)：
コラーゲンの製造と応用展開
シーエムシー出版 ISBN:9784781300719
Lectures and oral presentations (17)：
Recombinant aipha1 chain of human type I collagen in the silkworms Bombyx mori: production of human gelatin as a novel biomaterial
(Yokosuka Science Festa 2009 2009)
カイコによって生産されたヒト型ゼラチンの細胞生物学的評価
(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会 2008)
カイコによって生産されたヒト型ゼラチンの細胞生物学的評価
(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会 2008)
遺伝子組換えカイコを用いたヒトI型コラーゲンα1鎖の産生
(第30回日本分子生物学会年会・第80回日本生化学会大会 2007)
遺伝子組換えカイコを用いたヒトI型コラーゲンalpha1鎖の産生
(第30回日本分子生物学会年会・第80回日本生化学会大会合同大会 2007)
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Education (5)：
- 2002 Hiroshima University
- 2002 Hiroshima University Doctor course
- 1998 Hiroshima University Master course
- 1996 Hiroshima University Faculty of Science
- 1996 Hiroshima University Faculty of Science
Professional career (1)：
Doctor of science (Hiroshima University)
Association Membership(s) (4)：
マトリックス研究会
, 日本再生医療学会
, 日本分子生物学会
, The Molecular Biology Society of Japan
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