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J-GLOBAL ID：200901029158740903   Update date: Feb. 01, 2024

Ito Akihiko

イトウ アキヒコ | Ito Akihiko
Affiliation and department：
Kindai University Faculty of Medicine Department of Medicine

About Kindai University Faculty of Medicine Department of Medicine


Job title： Associate Professor
Research field  (1)： Experimental pathology
Research keywords  (2)： 癌転移の分子機構 ,  Molecular Basis of Metastasis
Research theme for competitive and other funds  (38)：
  • 2021 - 2025 食道癌術前化学療法の治療効果予測-低酸素イメージングと癌シグナル伝達因子との相関
  • 2021 - 2024 接着分子内在化を機序とする抗体創薬の基礎研究
  • 2022 - 2024 脳腫瘍を標的とする抗体薬物複合体の開発
  • 2019 - 2022 Immune related gene-expression profiling for the combination of chemotherapy and PD-1/PD-L1 inhibition.
  • 2018 - 2021 Analysis of tissue degeneration by internal pressure elevation
Show all
Papers (281)：
  • Fuka Takeuchi, Aki Sugano, Azusa Yoneshige, Man Hagiyama, Takao Inoue, Akihiro Wada, Yutaka Takaoka, Akihiko Ito. Potential Contribution of Cell Adhesion Molecule 1 to the Binding of SARS-CoV-2 Spike Protein to Mouse Nasal Mucosa. Cells Tissues Organs. 2023
  • Ilamangai Nagaretnam, Azusa Yoneshige, Fuka Takeuchi, Ai Ozaki, Masaru Tamura, Shiori Suzuki, Toshiaki Shigeoka, Akihiko Ito, Yasumasa Ishida. Granulomatous inflammatory responses are elicited in the liver of PD-1 knockout mice byde novogenome mutagenesis. 2023
  • Xilin Wu, Elena A. B. Azizan, Emily Goodchild, Sumedha Garg, Man Hagiyama, Claudia P. Cabrera, Fabio L. Fernandes-Rosa, Sheerazed Boulkroun, Jyn Ling Kuan, Zenia Tiang, et al. Somatic mutations of CADM1 in aldosterone-producing adenomas and gap junction-dependent regulation of aldosterone production. Nature Genetics. 2023. 55. 6. 1009-1021
  • Kohsuke Isomoto, Koji Haratani, Takahiro Tsujikawa, Yusuke Makutani, Hisato Kawakami, Masayuki Takeda, Kimio Yonesaka, Kaoru Tanaka, Tsutomu Iwasa, Hidetoshi Hayashi, et al. Mechanisms of primary and acquired resistance to immune checkpoint inhibitors in advanced non-small cell lung cancer: A multiplex immunohistochemistry-based single-cell analysis. Lung cancer (Amsterdam, Netherlands). 2022. 174. 71-82
  • 金村 宙昌, 林 秀敏, 原谷 浩司, 中川 和彦, 冨田 秀太, 谷崎 潤子, 鈴木 慎一郎, 川中 雄介, 津谷 あす香, 福田 泰, et al. 進展型小細胞肺癌における免疫チェックポイント阻害薬の効果と腫瘍微小免疫環境の関連. 肺癌. 2022. 62. 5. 442-442
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MISC (159)：
  • 武内風香, 萩山満, 菅野亜紀, 高岡裕, 佐々木健郎, 伊藤彰彦. Indigo Plant Leaf Extract Inhibits SARS-CoV-2 Spike Binding to Angiotensin-Converting Enzyme 2. 日本病理学会会誌. 2022. 111. 1
  • 萩山満, 米重あづさ, 武内風香, 伊藤彰彦. Adhesion molecule CADM1 contributes to proliferation of endometrial glandular cells. 日本病理学会会誌. 2022. 111. 1
  • 萩山 満, 米重 あづさ, 伊藤 彰彦. 上皮単層における細胞生存への寄与 接着分子CADM1. 日本病理学会会誌. 2021. 110. 1. 247-247
  • 大谷 知之, 村上 幸祐, 木村 雅友, 松木 充, 佐藤 隆夫, 松村 謙臣, 伊藤 彰彦. 子宮留膿腫に関連して生じた内膜偽リンパ腫. 日本病理学会会誌. 2021. 110. 1. 338-338
  • 米重 あづさ, 萩山 満, 伊藤 彰彦. 水柱下培養装置を用いた高眼圧性緑内障モデルの構築. 日本病理学会会誌. 2021. 110. 1. 363-363
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Books (6)：
  • Highlights in Cell Adhesion and Migration.
    Frontiers Media SA 2022
  • Linking experimental pathology experts in designing in vitro models of pathological conditions with researchers investigating molecular mechanisms of pathogenesis
    2019
  • Cell Adhesion and Migration in the Development of Multicellular Organisms.
    2019
  • はじめの一歩のイラスト病理学
    羊土社 2012
  • Alzheimer's disease pathogenesis-core concepts, shifting paradigms and therapeutic targets, Expression and cerebral function of amyloid precursor protein after rat traumatic brain injury
    Intech open access publisher 2011
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Lectures and oral presentations  (124)：
  • Asp isomerization in CADM1 shedding products is potentially involved in neurodegeneration induced by elevated pressure
    (2023)
  • Testicular teratomagenesis with overexpression of GANP
    (2023)
  • Therapeutic strategy for pleural mesothelioma using antibodies against cell adhesion molecule1
    (2023)
  • 接着分子CADM1/TSLC1に対する抗体を用いた胸膜中皮腫の新たな治療戦略.
    (第45回日本分子生物学会年会 日本生物物理学会 共催 2022)
  • Decrease of BRCA2-interaction DSS1 contributes to reducing the side effects of chemotherapy in breast carcinomas
    (2022)
ｍore...
Education (4)：
  • - 1998 Kobe University School of Medicine Faculty of Medicine
  • - 1998 Kobe University Faculty of Medicine
  • - 1995 Osaka University
  • - 1995 Osaka University Graduate School, Division of Medicine
Professional career (1)：
  • (BLANK)
Awards (4)：
  • 2002 - 日本がん転移学会学術奨励賞
  • 2001 - 日本病理学会学術奨励賞
  • 日本がん転移学会研究奨励賞
  • 日本病理学会学術奨励賞
Association Membership(s) (2)：
日本病理学会 ,  日本癌学会
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