Rchr
J-GLOBAL ID:200901029596284821
Update date: Feb. 12, 2024
Muromoto Ryuta
ムロモト リユウタ | Muromoto Ryuta
Affiliation and department:
Job title:
Associate professor
Research field (1):
Pharmaceuticals - health and biochemistry
Research keywords (10):
サイトカイン
, TYK2
, インターフェロン
, 免疫
, シグナル伝達
, 核内受容体
, 自己免疫疾患
, 炎症
, 環境化学物質
, IL-17
Research theme for competitive and other funds (14):
- 2023 - 2025 ポストコロナの感染症・がん予防に向けての貪食促進型赤血球ワクチンの創製
- 2020 - 2023 自己免疫疾患発症制御に関与するTYK2新規機能の同定
- 2019 - 2022 アレルギー、免疫疾患制御に向けてのシグナル調節機構の解明
- 2019 - 2022 Effects of microplastic-derived chemicals on functions of regulatory T cells via nuclear receptor Nr4a.
- 2017 - 2020 IL-17A誘導性mRNA安定化応答が免疫疾患形成に果たす役割の解明
- 2015 - 2018 Effects of chemical mixtures contained in foods on immune response via nuclear receptors.
- 2012 - 2015 Effects of environmental chemicals on Th17 cells differenciation via aryl hydrocarbon receptor
- 2013 - 2015 The role of TYK2 in the modulation of inflammatory responses
- 2011 - 2014 癌・免疫疾患発症とシグナル異常:STAT3とNFーκBを中心として
- 2011 - 2011 The role of TYK2 in innate and acquired immune system
- 2009 - 2011 Effects of environmental chemicals on differentiation of helper-T 17 cells via retinoic acid receptor-related orphan receptors
- 2008 - 2010 Activation and regulation of the disease-related IL-6/STAT3 signaling
- 2008 - 2009 Analysis of DAXX-mediated cell death in pro-B cell line
- 2006 - 2006 インターフェロンによるB細胞増殖抑制機構の解明-新たな機能分子Daxx-
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Papers (105):
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Kota Kagohashi, Yuto Sasaki, Kiyotaka Ozawa, Takuya Tsuchiya, Shoya Kawahara, Kodai Saitoh, Michiko Ichii, Jun Toda, Yasuyo Harada, Masato Kubo, et al. Role of Signal-Transducing Adaptor Protein-1 for T Cell Activation and Pathogenesis of Autoimmune Demyelination and Airway Inflammation. The Journal of Immunology. 2024
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Jun-Ichi Kashiwakura, Shoya Kawahara, Iori Inagaki, Kyosuke Inui, Kodai Saitoh, Kota Kagohashi, Yuto Sasaki, Fuki Kobayashi, Yuichi Kitai, Ryuta Muromoto, et al. STAP-2 negatively regulates BCR-mediated B cell activation by recruiting tyrosine-protein kinase CSK to LYN. FEBS letters. 2023. 597. 19. 2433-2445
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Yuto Sasaki, Kodai Saitoh, Kota Kagohashi, Toyoyuki Ose, Shoya Kawahara, Yuichi Kitai, Ryuta Muromoto, Yuichi Sekine, Michiko Ichii, Akihiko Yoshimura, et al. STAP-2-Derived Peptide Suppresses TCR-Mediated Signals to Initiate Immune Responses. The Journal of Immunology. 2023
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Taiga Maemoto, Yuichi Kitai, Runa Takahashi, Haruka Shoji, Shunsuke Yamada, Shiho Takei, Daiki Ito, Ryuta Muromoto, Jun-Ichi Kashiwakura, Haruka Handa, et al. A peptide derived from adaptor protein STAP-2 inhibits tumor progression by downregulating epidermal growth factor receptor signaling. The Journal of biological chemistry. 2022. 299. 1. 102724-102724
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Shigeru Hashimoto, Ari Hashimoto, Ryuta Muromoto, Yuichi Kitai, Kenji Oritani, Tadashi Matsuda. Central Roles of STAT3-Mediated Signals in Onset and Development of Cancers: Tumorigenesis and Immunosurveillance. Cells. 2022. 11. 16
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MISC (97):
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室本竜太. Study on immunotoxicity through mRNA stability control mechanism. ImmunoTox Letter (Web). 2023. 55
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松田 正, 室本 竜太, 鍛代 悠一, 織谷 健司. 【IL-6阻害療法の基礎と臨床】IL-6とそのシグナル伝達系の分子基盤. リウマチ科. 2023. 69. 1. 1-12
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成家康太, 室本竜太, 松田正. Benzo[a]pyrene enhances IL-17-mediated responses by suppressing expression of Regnase-1 through AhR. 日本薬学会年会要旨集(Web). 2022. 142nd
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室本竜太. Study on immunotoxicity through mRNA stability control mechanism. 日本免疫毒性学会学術年会講演要旨集. 2022. 29th
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田中伸英, 村上侑斗, 平島洸基, 福田隼, 藤原広一, 渡邉瑞貴, 室本竜太, 松田正, 周東智. 抗炎症脂質レゾルビンE2の1,4,7-トリエン-ベンゼン置換による安定等価体の創製研究. 反応と合成の進歩シンポジウム講演要旨集. 2022. 48th
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Patents (1):
Education (2):
- 2002 - 2007 Hokkaido University Graduate School, Division of Pharmaceutical Sciences
- 1998 - 2002 Hokkaido University Faculty of Pharmaceutical Sciences
Professional career (1):
- PhD (Hokkaido University)
Work history (4):
- 2022/03 - 現在 Hokkaido University Faculty of Pharmaceutical Sciences Associate professor
- 2016/04 - 2022/02 Hokkaido University Faculty of Pharmaceutical Sciences Lecturer
- 2007/04 - 2016/03 Hokkaido University Faculty of Pharmaceutical Sciences Assistant Professor
- 2006/04 - 2007/03 日本学術振興会特別研究員
Committee career (3):
- 2020/10 - 現在 日本免疫毒性学会 評議員
- 2019/04 - 2022/01 日本薬学会 日本薬学会北海道支部 幹事
- 2020/02 - 2021/01 日本薬学会 日本薬学会北海道支部 庶務幹事
Awards (4):
- 2022/09 - 日本免疫毒性学会 第12回(2022年)奨励賞
- 2018/09 - 日本免疫毒性学会 第25回日本免疫毒性学会学術年会 年会賞
- 2013/04 - 日本免疫学会 平成25年度 Tadamitsu Kishimoto International Travel Award
- 2011 - 平成23年度日本薬学会北海道支部奨励賞
Association Membership(s) (3):
The Japanese Society of Immunotoxicology
, 日本薬学会
, 日本免疫学会
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