Rchr

J-GLOBAL ID：200901030799528163 Update date: Jan. 09, 2023

Funabashi Toshiya

フナバシトシヤ | Funabashi Toshiya

Affiliation and department：
Homepage URL (1)： http://www.marianna-u.ac.jp/physiology/index.html

Research field (4)： Basic brain sciences , Physiology , Neuroscience - general , Neuropathology

Research keywords (10)： sex difference , pulsatile LH secretion , surge of LH secretion , Gonadotropin-releasing hormone , preoptic area , CRH , bed nucleus stria terminalis , pain , Oligodendrocyte progenitor cell , Feeding

Research theme for competitive and other funds (50)：

2022 - 2025 Mechanism for effects of of ketone diet feeding on changes in skeletal muscles induced by excercise
2020 - 2023 痛み行動の性差発現における分界条床核背外側CRHニューロンの役割
2017 - 2023 Studies of physiological role of microglia on hippocampus-dependent learning
2017 - 2020 Studies of the mechanism for the establishment of sexual differences in hippocampal learning processes
2016 - 2019 Hypothalamic hypogonadism: Elucidation of the mechanisms controlling GnRH neural activity via Toll-like receptor 4

2014 - 2017 Mechanism for microglia involvement of the brain higher function

2014 - 2017 Molecular mechanism for the sex difference in learning ability by feeding environment

2015 - 2017 性成熟後の母性行動発現に及ぼす離乳期の母性様行動発現とニコチン暴露の影響の機序解明

2014 - 2016 Role of microglia in functional hypothalamic hypogonadism

2013 - 2016 The molecular basis of improving learning function with maternal experiences of pregnancy-delivery- pup rearing

2011 - 2013 Development of the method of selecting the sperm in the ART (Assisted reproductive technology)

2011 - 2013 離乳期の経験による成熟後の学習機能の変化に及ぼすニコチン曝露の影響

2011 - 2013 Sex differences in learning and its mechanism

2008 - 2010 The effect of social isolation on the circuit formation in the brain

2008 - 2010 Acetylcholine mediates learning-dependent AMPA receptor delivery into the CA3-CA1 synapses

2008 - 2010 情動・認知機能を定量化する包括的な行動毒性試験の構築

2007 - 2008 Sex difference in pain response and its mechanism (2)

2007 - 2008 Sex and functional differences in the lateral hypothalamic area which controls feeding behavior

2006 - 2007 Role of gonadal steroids on the in vivo acetylcholine release in the hippocampus

2006 - 2007 本能空腹感と情動空腹感によって調節される摂食行動の神経基盤の解明

2005 - 2007 ラット嗅板を用いたGnRHパルス分泌におけるcAMPの役割に関する研究

2005 - 2007 Neural basis for generating gonadotropin-releasing hormone surge

2005 - 2006 Mechanism for sex difference in pain responses (1) Mapping of and time course of the exression of phosphorylated CREB induced by formalin

2003 - 2005 大脳辺縁系-視床下部系神経核の性特異的「かたち」づくりの仕組み:性同一性障害者の性腺刺激ホルモン分泌様式を手がかりとして

2003 - 2004 Sex difference in the GABAergic control of gonadotropin release in rats

2004 - 2004 性同一性障害者の性腺刺激ホルモン分泌調節中枢性機序-「汎視床下部性分化異常」という新しい疾患概念の提出

2002 - 2003 Sex differences in the stress responses in the amygdala

2002 - 2003 Non-estrogenic effects of endocrine disrupters on the central nervous system

2001 - 2003 ヒトにおけるニコチンの生殖内分泌機能におよぼす影響

2001 - 2001 培養胎仔鼻板のGnRHニューロンを用いてGnRHサージ発生器を作成する試み

1999 - 2000 Role of Ca^<2+> channel in the function of gonadotropin-releasing hormone surge generator in rats

1999 - 2000 Analysis of neuronal circuit for the gonadotropin-releasing hormone surege generator (GnRH) using an in vitro GnRH surge generator model

1996 - 2000 生殖機能とニコチン:ラットの性腺刺激ホルモン分泌に対するニコチンの作用

1998 - 1999 Effects of menstrual cycles on the human circadian clock

1997 - 1998 Determination of the Characteristic of the GnRH Surge Generator by Multifarious Approaches

1997 - 1998 GnRHサージ機構の老化における胎児型GADの役割

1998 - 1998 培養胎仔鼻板GnRHパルス発生器電気活動の記録

1998 - 中枢性排卵調節機構の老化機序

1996 - 1996 視床下部エストロジェン受容体mRNAの多様性

1994 - 1995 Demonstration that the neural network for the LHRH surge generator is distinct from that for the pulse generator.

1995 - 視床下部エストロジェン受容細胞のエストロジェンによる老化

1995 - 1995 視床下部におけるLHRHmRNAの多様性:その生理的意義

1994 - 障害されたLHRH神経細胞の機能修復過程に関する研究

1994 - 1994 内側視索前野の性ホルモン受容体遺伝子発現のエストロジェンによる調節

1992 - 1993 Electrophysiological demonstration of the functional bimorphism of LHRH neurons in rats

1993 - 核磁気共鳴画像解析法による眼球内水分動態の解析

1993 - 1993 中枢神経系の超早期遺伝子に対するアンチヌクレオチドの効果

1990 - 1991 Electrophysiological identification of LHRH neurons that are involved in the LH surge induced by positive feedback action of estrogen.

1989 - 1990 Visualization and Quantitative Analysis of Neuropeptide Secretion from Cultured Individual Neurons

1987 - てんかんモデル、キンドリング、の形成に対する神経成長因子の関与

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Papers (145)：

Hiroko Hagiwara, Kenji Sakimura, Manabu Abe, Keiichi Itoi, Yoshinori Kamiya, Tatsuo Akema, Toshiya Funabashi. Sex differences in pain-induced modulation of corticotropin-releasing hormone neurons in the dorsolateral part of the stria terminalis in mice. Brain research. 2021. 1773. 147688-147688
Mitsutoshi Kurosaka, Yuji Ogura, Shuichi Sato, Kazuhisa Kohda, Toshiya Funabashi. Transcription factor signal transducer and activator of transcription 6 (STAT6) is an inhibitory factor for adult myogenesis. Skeletal muscle. 2021. 11. 1. 14-14
Yuji Ogura, Shuichi Sato, Mitsutoshi Kurosaka, Takashi Kotani, Hiroto Fujiya, Toshiya Funabashi. Age-related decrease in muscle satellite cells is accompanied with diminished expression of early growth response 3 in mice. Molecular biology reports. 2020. 47. 2. 977-986
Yuji Ogura, Chiaki Kakehashi, Toshinori Yoshihara, Mitsutoshi Kurosaka, Ryo Kakigi, Kazuhiko Higashida, Sei-Etsu Fujiwara, Tatsuo Akema, Toshiya Funabashi. Ketogenic diet feeding improves aerobic metabolism property in extensor digitorum longus muscle of sedentary male rats. PloS one. 2020. 15. 10. e0241382
工藤貴章, 藤谷博人, 後藤勝正, 黒坂光寿, 小倉裕司, 谷田部かなか, 大野真弘, 小林創, 舩橋利也, 幸田和久, et al. 微弱電流刺激(MENS)と高気圧酸素療法(HBO)の併用による骨格筋損傷の修復促進効果. 聖マリアンナ医科大学雑誌. 2018. 46. 3. 206-206

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MISC (179)：

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Books (15)：

QUICK生理学・解剖学 : 人体の構造と機能・病態生理
羊土社 2022 ISBN:9784758121187
Intensive lectures : illustrated physiology
2022 ISBN:9784758317917
標準生理学第9版
医学書院 2019
Guyton anf Hall Textbook of Medical Physiology
Elsevier 2018
オックスフォード生理学第4版
丸善 2016

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Lectures and oral presentations (29)：

GnRHニューロンの制御におけるミクログリアの関与
(第90回日本生理学会大会・学会提携シンポジウム 2013)
摂食行動を調節する視床下部外側野の性差
(第28回日本肥満学会シンポジウム 2007)
性差から見た摂食行動調節の神経基盤
(第4回行動神経内分泌学会講演 2007)
Estrogen and glucose-sensing neurons
(89th Annual Meeting for the Endocrine Society Symposium 2007)
摂食行動の性差
(第84回日本生理学会大会シンポジウム 2007)

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Works (1)：

ラット視床下部のプロエンケファリンのmRNAとpre-mRNAHormone
舩橋利也 1996 -

Education (2)：

1986 - 1990 Yokohama City University Graduate Graduate School of Medicine
1978 - 1984 Yokohama City University

Professional career (1)：

医学博士 (横浜市立大学)

Work history (6)：

2010/04 - 現在 St.Marianna University School of Medicine
1990/04 - 2010/03 横浜市立大学医学部生理学
1991/04 - 1993/03 ロックフェラー大学神経生物学ポストドクトラルフェロー
1986/04 - 1990/03 Yokohama City University Graduate
1985/04 - 1986/03 一般外科臨床研修医

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Awards (2)：

2002 - 横浜市立大学横浜医学会賞
2001 - 日本神経内分泌学学会川上賞

Association Membership(s) (4)：

The Japan Endocrine Society , Society for Neuroendocrinology , THE JAPAN NEUROSCIENCE SOCIETY , THE PHYSIOLOGICAL SOCIETY OF JAPAN

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