Muraki Katsuhiko

ムラキカツヒコ | Muraki Katsuhiko

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www.phar.agu.ac.jp/lab/cell_pharm/cellpharmacol.html

Research field (1)： Pharmacology

Research keywords (4)： ion channel , イオンチャンネル , Piezo channel , TRP channel

Research theme for competitive and other funds (35)：

2020 - 2023 がん細胞における機械刺激感受性PIEZOチャネルの機能および病態生理学意義の解明
2016 - 2019 Molecular mechanisms underlying alternation of ion channel expression and function by chronic inflammation
2014 - 2017 iPS因子によるカチオンチャネルの転写制御とチャネル発現異常による疾患
2011 - 2014 Degradation of cationic channel protein, which causes the cellular dysfunction
2011 - 2014 カチオンチャネルタンパク質の分解制御とその破綻による細胞異常

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Papers (122)：

Noriyuki Hatano, Masaki Matsubara, Hiroka Suzuki, Yukiko Muraki, Katsuhiko Muraki. HIF-1α Dependent Upregulation of ZIP8, ZIP14, and TRPA1 Modify Intracellular Zn2+ Accumulation in Inflammatory Synoviocytes. International Journal of Molecular Sciences. 2021. 22. 12. 6349-6349
Ohya S, Ito K, Hatano N, Ohno A, Muraki K, Imaizumi Y. Castration Induces Down-Regulation of A-Type K⁺ Channel in Rat Vas Deferens Smooth Muscle. International journal of molecular sciences. 2019. 20. 17
H Cabanas, K Muraki, C Balinas, N Eaton-Fitch, D Staines, S Marshall-Gradisnik. Validation of impaired Transient Receptor Potential Melastatin 3 ion channel activity in Natural Killer cells from Chronic Fatigue Syndrome/ Myalgic Encephalomyelitis patients. Mol Med. 2019
T Sekine, T Hirata, S Ishikawa, S Ito, K Ishimori, K Matsumura, K Muraki. Regulation of NRF2, AP-1, and NF-KB by cigarette smoke exposure in three-dimensional human bronchial epithelial cells. J. Appl. Toxicol. 2019. 39. 717-725
I Maki-Opas, M Hamalainen, LJ Moilanen, R Haavikko, TJ Ahonen, S Alakurtti, VM Moreira, K Muraki, J Yli-Kauhaluoma, E Moilanen. Pyrazine-fused triterpenoids block the TRPA1 ion channel in vitro and inhibit TRPA1-mediated acute inflammation in vivo. ACS Chem Neurosci. 2019

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MISC (88)：

Jing Li, Bing Hou, Sarka Tumova, Katsuhiko Muraki, Alexander Bruns, Melanie J. Ludlow, Alicia Sedo, Adam J. Hyman, Lynn McKeown, Richard S. Young, et al. Piezo1 Integration of Vascular Architecture with Physiological Force. FASEB JOURNAL. 2015. 29
大矢進, 松葉紗代, 丹羽里実, 村木克彦, 金塚早希, 中園裕利華, 波多野紀行, 藤井正徳, PENG Zhan, 鈴木孝禎. ヒストン脱アセチル化酵素阻害によるがん細胞カルシウム活性化クロライドチャネルTMEM16Aの発現抑制. 日本生化学会大会(Web). 2014. 87th
Secretion of skin moisture-related substances mediated by environmental sensor TRPV channels in keratinocyte. Cosmetology : Annual report of cosmetology. 2013. 21. 114-116
Katsuhiko Muraki, Hiroka Suzuki, Noriyuki Hatano, Yukiko Muraki, Yuka Itoh, Hidetoshi Hayashi, Kikuo Onozaki. Potent activation of TRPA1 channel by NADPH oxidase inhibitors. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2013. 121. 171P-171P
Noriyuki Hatano, Yuka Itoh, Hiroka Suzuki, Yukiko Muraki, Hidetoshi Hayashi, Kikuo Onozaki, Ian Wood, David Beech, Katsuhiko Muraki. Inflammatory stimulation induces expression of TRPA1 channel to regulate cytokine release. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2013. 121. 158P-158P

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Books (4)：

Physiological functions and pathophysiological aspects of TRPC1/4/5 channels and drug discovery targeting on them
2019
薬学のための医療統計学
廣川書店 2014
血管に対するK<SUP>+</SUP>チャネル開口薬の作用世界に誇る日本発K<SUP>+</SUP>チャネル開口薬ニコランジル
ライフメディコム社 2006
血管平滑筋イオンチャネルとリモデリング(第2版) イオンチャネル最前線
医歯薬出版 2005

Lectures and oral presentations (21)：

TRP channels and Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: Overview and Future Perspectives
(CFS/ME International 2018: RID - Research Innovation and Discovery Conference 2018)
TRP channels and Chronic Fatigue Syndrome/Myalgic Encephalomyeliti: Overview and Future Perspectives
(CFS/ME International 2018: RID - Research Innovation and Discovery Conference 2018)
TRP channels in arthritis
(Scandinavian Congress of Rheumatology 2018)
Pyrazine-fused triterpenoids block TRPA1 ion channel in vitro and inhibit TRPA1-mediated inflammation in vivo
(WCP2018 2018)
TRPC1/C4を介した細胞機能変化と炎症刺激
(TRP研究会2018 2018)

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Education (1)：

1989 - 1992 Nagoya City University Graduate School of Pharmaceutical Sciences

Professional career (1)：

Ph.D. (Nagoya City University)

Work history (6)：

2012/04/01 - 現在愛知学院大学大学院薬学研究科医療薬学専攻教授
2005/04/01 - 現在愛知学院大学薬学部薬効解析学教授
2000/01 - 2005/03 名古屋市立大学薬学部助教授・准教授
1996/02 - 1999/12 名古屋市立大学薬学部専任講師
1993/03 - 1996/01 名古屋市立大学薬学部助手

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Committee career (7)：

2007/04 - 現在 Japanese Society of Smooth muscle
2007/04 - 現在日本平滑筋学会学会評議員
1997/04 - 現在 Japanese Society of Pharmacology
1997/04 - 現在日本薬理学会学術評議員
2018/04/01 - 2020/03/31 名古屋市立大学薬学部自己点検評価委員会外部委員

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Awards (3)：

2002/03 - 日本薬理学会学術奨励賞
2001/07 - 日本心脈管作動物質学会研究奨励賞
1997/07 - 日本薬学会東海支部学術奨励賞

Association Membership(s) (6)：

JAPAN SOCIETY OF SMOOTH MUSCLE RESEARCH , Japananse Society of Pharmaceutical Sciences , Japanese Society of Pharmacology , The Pharmaceutical Society of Japan , Japansense Phramacological Society , 日本薬剤師会

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