Rchr
J-GLOBAL ID:200901031683490050   Update date: Feb. 29, 2024

Saino Tomoyuki

サイノ トモユキ | Saino Tomoyuki
Affiliation and department:
Job title: professor
Research field  (3): Morphology, anatomy ,  Cell biology ,  Anatomy
Research keywords  (9): 自律神経節 ,  外分泌腺 ,  細動脈 ,  カルシウムシグナリング ,  カルシウムイメージング ,  cell signalling ,  arterioles ,  calcium imaging ,  bioimaging
Research theme for competitive and other funds  (29):
  • 2022 - 2025 Long-term potentiation mechanism by glutamate receptors of the carotid body in model rats of sleep apnea syndrome
  • 2022 - 2025 Do nerve-related trace amines control exocrine cell function? -elucidation of neuro-exocrine linkage-
  • 2019 - 2023 マスト細胞の脱顆粒応答は分泌刺激の種類で変化するか?-イメージングによる解析-
  • 2020 - 2022 唾液アミラーゼ活性は痛みの客観的評価指標となるか?
  • 2017 - 2020 微量アミン関連受容体は脳血管に影響を及ぼすのか?-脳細動脈を用いた形態機能解析
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Papers (74):
  • Takuya Yokoyama, Tomoyuki Saino, Nobuaki Nakamuta, Yoshio Yamamoto. Immunohistochemical localization of P2Y12 purinoceptors in the rat carotid body. Autonomic Neuroscience. 2024. 103158-103158
  • Satsuki Maesawa, Takuya Yokoyama, Wakana Sakanoue, Yoshio Yamamoto, Masato Hirakawa, Hirohisa Shiraishi, Kenichi Sato, Tomoyuki Saino. ADP-mediated Modulation of Intracellular Calcium Responses in Chromaffin Cells: The Role of Ectonucleoside Triphosphate Diphosphohydrolase 2 on Rat Adrenal Medulla Function. Journal of Histochemistry & Cytochemistry. 2023. 72. 1. 41-60
  • Naoto Yoshino, Takuya Yokoyama, Hironori Sakai, Ikumi Sugiyama, Takashi Odagiri, Masahiro Kimura, Wataru Hojo, Tomoyuki Saino, Yasushi Muraki. Suitability of Polymyxin B as a Mucosal Adjuvant for Intranasal Influenza and COVID-19 Vaccines. Vaccines. 2023. 11. 11. 1727-1727
  • Hironori Higashio, Takuya Yokoyama, Tomoyuki Saino. A convenient fluorimetry-based degranulation assay using RBL-2H3 cells. Bioscience, Biotechnology, and Biochemistry. 2023
  • Wakana SAKANOUE, Takuya YOKOYAMA, Masato HIRAKAWA, Satsuki MAESAWA, Kenichi SATO, Tomoyuki SAINO. 3-Iodothyronamine, a trace amine-associated receptor agonist, regulates intracellular Ca2+ increases via CaMK II through Epac2 in rat cerebral arterioles. Biomedical Research. 2023. 44. 5. 219-232
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MISC (116):
  • 吉野 直人, 横山 拓矢, 酒井 博則, 杉山 育美, 小田切 崇, 木村 将大, 北條 渉, 齋野 朝幸, 村木 靖. ポリミキシンBの粘膜アジュバント作用 インフルエンザおよびCOVID-19経鼻ワクチン開発における可能性. 臨床とウイルス. 2023. 51. 3. 195-195
  • 坂野上 和奏, 齋野 朝幸, 横山 拓矢, 平川 正人, 伊藤 元, 佐藤 健一. 微量アミン関連受容体(TAAR)アゴニストである3-iodothyronamineはラット脳細動脈においてTAARとは別の受容体にも働く. 日本歯科麻酔学会雑誌. 2022. 50. 抄録号. 182-182
  • 東尾 浩典, 横山 拓矢, 齋野 朝幸. ライブイメージング技術に立脚した簡便なマスト細胞脱顆粒アッセイ系の構築. 日本生化学会大会プログラム・講演要旨集. 2021. 94回. [P-694]
  • 伊藤 元, 横山 拓矢, 平川 正人, 坂野上 和奏, 齋野 朝幸, 佐藤 健一. ラット切歯乳頭における味蕾様細胞集塊の形態. 日本歯科麻酔学会雑誌. 2021. 49. 抄録号. 119-119
  • 大越 魁, 横山 拓矢, 齋野 朝幸, 中牟田 信明, 山本 欣郎. ラット気管における刷子細胞の形態. 日本獣医学会学術集会講演要旨集. 2019. 162回. 343-343
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Books (6):
  • カルシウムイメージング技術の基礎
    組織細胞化学 2011,日本組織細胞化学会編,学際企画 2011
  • 組織標本を用いたカルシウムバイオイメージングの実際(共著)
    組織細胞化学2004, 組織細胞化学会編集,学際企画 2004
  • 高速共焦点レーザー顕微鏡によるCa<sup>2+</sup>のマッピング(共著)
    組織細胞化学2000 2000
  • Mutations of Arginine-198 in Sarcoplasmic Reticulum Ca<sup>2+</sup>-ATPase Cause Inhibition of Hydrolysis of the Phosphoenzyme Intermediate formed from Inorganic Phosphate.(jointly worked)
    Elsevier Science B.V. 2000
  • Deletions or Specific Substitutions of a Few Residues in the NH<sub>2</sub>-terminal Region Ala3-Thr9 of Sarcoplasmic Reticulum Ca<sup>2+</sup>-ATPase Cause Inactivation and Rapid Degradation of the Enzyme Expressed in COS-1 Cells.(jointly worked)
    Elsevier Science B.V. 2000
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Lectures and oral presentations  (30):
  • The investigation of the distribution of autonomic nerves on superior tarsal plate.
    (International council of ophthalmology, World ophthalmology congress. 2018)
  • Intracellular Calcium Dynamics and Expression of P2Y and IP3 Receptors in a Cycling G1-phase cell.
    (Japanese Association of Anatomists (JAA) The 62nd annual meeting of Tohoku and Hokkaido Regions 2016)
  • α1-Adrenoceptors relate Ca2+ modulation and mucin secretion in rat lacrimal grand.
    (The 120th Anuual Meeting of The Japanese Association of Anatomists and the 92nd Annual Meeting of the Physiological Society of Japan 2015)
  • Effects of protease-activated receptors (PARs) on intracellular calcium dynamics of acinar cells in rat lachrimal glands.
    (International Symposium Anatomical Science for advance in health and clinical therapy 2013)
  • Protease-activated receptor 2 affects protein secretion through a multifunctional Ca2+/calmodulin-dependent protein kinase (CAMK II) pathway in rat parotid gland acinar cells.
    (FAOBMB Mini-Symposium - Molecular Bases for Medical and Pharmaceutical Sciences - 2013)
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Education (2):
  • 1994 - 1998 Asahikawa Medical University
  • 1985 - 1991 Asahikawa Medical University School of Medicine Medical Course
Professional career (1):
  • MD. Ph D.
Work history (8):
  • 2014/04 - 現在 Iwate Medical University Department of Anatomy (Cell Biology) Professor
  • 2008 - 2014 Iwate Medical University School of Medicine
  • 2007 - 2008 Iwate Medical University School of Medicine
  • 2006 - 2007 Iwate Medical University School of Medicine
  • 1998 - 2006 Iwate Medical University School of Medicine
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Committee career (9):
  • 2022/04 - 現在 盛岡第一高校学校運営協議会委員
  • 2019/04 - 現在 The medical association of Iwate Medical University Vice-president
  • 2019/04 - 現在 Anatomical Science International Managing Editor
  • 2014/12 - 現在 日本バイオイメージング学会 評議員
  • 2011/04 - 現在 日本解剖学会 学術評議員
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Awards (3):
  • 2006 - 第21回日本顕微鏡学会論文賞
  • 2004 - 第3回インテリジェント・コスモス奨励賞
  • 2003 - 岩手医科大学圭陵会学術賞
Association Membership(s) (10):
歯科麻酔学会 ,  THE JAPAN SOCIETY FOR MEDICAL EDUCATION ,  JAPANESE SOCIETY FOR MICROCIRCULATION ,  The Japanese Molecular Biological Society ,  日本顕微鏡学会 ,  The American Society for Cell Biology ,  The Japanese BioImaging Society ,  The Japanease Association of Anatomists ,  The Japanese Biochemical Society ,  The Japanese Pediatric Society
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