Rchr
J-GLOBAL ID:200901031799730651   Update date: Feb. 24, 2024

Yotsumoto Satoshi

ヨツモト サトシ | Yotsumoto Satoshi
Affiliation and department:
Job title: Associate Professor
Homepage URL  (1): http://toyaku-ls-immune.com
Research field  (1): Immunology
Research keywords  (6): Neutrophil ,  Neutrophil extracellular traps ,  単球 ,  がん転移 ,  NETosis ,  oxidized phospholipids
Research theme for competitive and other funds  (7):
  • 2022 - 2025 Development of cancer treatments targeting regulatory monocytes
  • 2022 - 2025 細胞内サイバネティック・アバターの遠隔制御によって見守られる社会の実現
  • 2022 - 2024 好中球細胞外トラップを標的とした新興感染症重症化予防薬の開発
  • 2019 - 2022 Analysis of molecular mechanisms of lipid peroxidation-dependent NET formation
  • 2017 - 2018 新規感染症治療薬”NET促進剤”の創出
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Papers (25):
  • Naoki Ikeda, Hiroaki Kubota, Risa Suzuki, Mitsuki Morita, Ayana Yoshimura, Yuya Osada, Keigo Kishida, Daiki Kitamura, Ayaka Iwata, Satoshi Yotsumoto, et al. The early neutrophil-committed progenitors aberrantly differentiate into immunoregulatory monocytes during emergency myelopoiesis. Cell Reports. 2023. 42. 3. 112165-112165
  • Shohei Takase, Young Sook Yun, Fuki Moriya, Saaya Sekine, Satoshi Yotsumoto, Katsunori Miyake, Tadahiro Yahagi, Akihiro Ito, Hideshi Inoue. 17β-neriifolin from unripe fruits of Cerbera manghas suppressed cell proliferation via the inhibition of HOXA9-dependent transcription and the induction of apoptosis in the human AML cell line THP-1. Journal of Natural Medicines. 2023. 77. 1. 180-187
  • Takuto Tokuhiro, Akane Ishikawa, Haruka Sato, Shunya Takita, Ayuri Yoshikawa, Ryoko Anzai, Shinichi Sato, Ryohei Aoyagi, Makoto Arita, Takumi Shibuya, et al. Oxidized Phospholipids and Neutrophil Elastase Coordinately Play Critical Roles in NET Formation. Frontiers in cell and developmental biology. 2021. 9. 718586-718586
  • YoungSook Yun, Mariko Shioura, Yukio Hitotsuyanagi, Satoshi Yotsumoto, Yuji Takahashi, Yutaka Aoyagi, Takeshi Kinoshita, Koichi Takeya, Hideshi Inoue. Garcinielliptone G from Garcinia subelliptica Induces Apoptosis in Acute Leukemia Cells. Molecules. 2021. 26. 9. 2422-2422
  • Takumi Shibuya, Asami Kamiyama, Hirotaka Sawada, Kenta Kikuchi, Mayu Maruyama, Rie Sawado, Naoki Ikeda, Kenichi Asano, Daisuke Kurotaki, Tomohiko Tamura, et al. Immunoregulatory Monocyte Subset Promotes Metastasis Associated With Therapeutic Intervention for Primary Tumor. Frontiers in immunology. 2021. 12. 663115-663115
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MISC (11):
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Patents (2):
  • がん転移抑制のための医薬組成物
  • 好中球細胞外トラップ形成促進剤
Books (5):
  • ファルマシア
    公益社団法人日本薬学会 2023
  • 細胞死のすべて-そのメカニズムと,生命現象・疾患との関わり
    医歯薬出版 2022 ISBN:9784006028305
  • シン・マクロファージ : あらゆる疾患を制御する機能的多様性
    羊土社 2022 ISBN:9784758104012
  • 細胞死 : その分子機構,生理機能,病態制御
    化学同人 2019 ISBN:9784759817317
  • 臨床免疫・アレルギー科
    科学評論社 2018
Lectures and oral presentations  (8):
  • 酸化リン脂質による好中球細胞死の誘導
    (第64回日本脂質生化学会 2022)
  • 脂質酸化依存的ネトーシスの誘導機構
    (第94回日本生化学会大会 2021)
  • 新しい単球サブセットによる がん転移の促進とその機構
    (第65回日本薬学会関東支部大会 2021)
  • ネトーシスにおける脂質酸化制御の分子機構
    (日本薬学会第140年会 2020)
  • Hyperoxidation of ether-linked phospholipids accelerates neutrophil extracellular trap formation
    (60th International Conference on the Bioscience of Lipids 2019)
more...
Professional career (1):
  • (BLANK)
Work history (5):
  • 2017/04 - 現在 Tokyo University of Pharmacy and Life Sciences Department of Immune regulation Research associate
  • 2013/08 - 2017/03 Tokyo University of Pharmacy and Life Sciences Department of Immune regulation Specially Appointed Research associate
  • 2010/01 - 2013/06 Tokyo Medical and Dental University Department of Biodefense Research Specially Appointed Research associate
  • 2008/04 - 2010/12 Akita University Specially Appointed Research associate
  • 1999/04 - 2008/03 Tokyo University of Pharmacy and Life Sciences Department of Drug Delivery Systems Research associate
Association Membership(s) (2):
THE JAPANESE BIOCHEMICAL SOCIETY ,  日本免疫学会
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