2017 - 2022 Changes in the gut microbiota acquired by exercise - Effects of detraining and retraining-
2019 - 2022 血清ペプチドバイオマーカーを用いた大腸がん早期発見の大規模前向き検証
2019 - 2022 腸内細菌叢からみた過敏性腸症候群の病態解明
2018 - 2021 Mucosa-associated microbiota and bacteriophage in the pathophysiology of irritable bowel syndrome (IBS)
2018 - 2021 環状ジヌクレオチドに対する免疫応答と腸管炎症制御メカニズムの解明
2018 - 2021 The effect of Wnt5a derived peptide to reduce intestinal inflammation
2017 - 2020 Analysis of endoscopic brush samples identified mucosa associated dysbiosis and the expression of tight junction protein in functional dyspepsia.
2017 - 2020 Development of new therapeutic strategies for cancer cachexia targeting gut microbiota
2017 - 2020 The effect of pyroglutamyl peptide on gut microbiota
2016 - 2020 機能性野菜を用いた腸内フローラ解析による生体恒常性維持効果の実証研究
2016 - 2019 The development of drug delivery system of carbon monoxide for inflammatory bowel disease
2006 - 2007 The invention of carbon monoxide inhalation system and the, utility of this system on the intestinal inflammau
2006 - 2007 Prediction of the cytotoxicity of additives in cosmetics on UV-exposed human skin keratinocytes
2006 - 2007 Hyperthermic treatment for early stage of rheumatoid arthritis
2005 - 2007 A study on the optimal predictive biomarkers for the effect of exercise-training on prevention of the lifestyle-related disease.
2005 - 2006 Cardioprotection with nuclear-targeted Akt/PKB
2004 - 2006 detection of marker groups indicating differentiating and regenerating stages of digestive cells using protein chips
2004 - 2005 Development of Hyperthermia Treatment for Early Stage of Rheumatoid Arthritis
2003 - 2004 Production of Oxidative Stress-Related ProteinChip and Its Evaluation on Biomarker for Common Disease
2002 - 2003 NF-κB as a therapeutic target in inflammatory bowel disease
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Papers (380)：
Hikaru Hashimoto, Tomohisa Takagi, Kohei Asaeda, Takeshi Yasuda, Mariko Kajiwara, Takeshi Sugaya, Katsura Mizushima, Ken Inoue, Kazuhiko Uchiyama, Kazuhiro Kamada, et al. D-alanine inhibits murine intestinal inflammation by suppressing IL-12 and IL-23 production in macrophages. Journal of Crohn's & colitis. 2024
Takahiro Nakano, Osamu Dohi, Tomohisa Takagi, Yuji Naito, Hayato Fukui, Hajime Miyazaki, Takeshi Yasuda, Takuma Yoshida, Yuka Azuma, Tsugitaka Ishida, et al. Characteristics of Gastric Mucosa-Associated Microbiota in Patients with Early Gastric Cancer After Successful Helicobacter pylori Eradication. Digestive diseases and sciences. 2023. 68. 12. 4398-4406
Hajime Miyazaki, Osamu Dohi, Tsugitaka Ishida, Mayuko Seya, Katsuma Yamauchi, Hayato Fukui, Takeshi Yasuda, Takuma Yoshida, Naoto Iwai, Toshifumi Doi, et al. Conventional versus underwater endoscopic resection for superficial non-ampullary duodenal epithelial tumours. Japanese journal of clinical oncology. 2023
Kazuhiko Uchiyama, Tomohisa Takagi, Katsura Mizushima, Kohei Asaeda, Mariko Kubota-Kajiwara, Takeshi Sugaya, Saori Kashiwagi, Yuki Minagawa, Yuma Hotta, Makoto Tanaka, et al. Clinical Background Factors as Predictors of the Efficacy of 5-Aminosalicylic Acid Suppositories in Patients with Ulcerative Colitis. Inflammatory intestinal diseases. 2023. 8. 2. 84-90
Osamu Handa, Hiroto Miura, Tingting Gu, Motoyasu Osawa, Hiroshi Matsumoto, Eiji Umegaki, Ryo Inoue, Yuji Naito, Akiko Shiotani. Reduction of butyric acid-producing bacteria in the ileal mucosa-associated microbiota is associated with the history of abdominal surgery in patients with Crohn’s disease. Redox Report. 2023. 28. 1
日本微小循環学会
, SOCIETY FOR FREE RADICAL RESEARCH JAPAN
, 日本消化器免疫学会
, THE JAPANESE SOCIETY OF INTERNAL MEDICINE
, JAPAN GASTROENTEROLOGICAL ENDOSCOPY SOCIETY
, 日本消化器病学会
