Rchr
J-GLOBAL ID：200901032740971309
Update date: Jan. 17, 2024
Yokomatsu Tsutomu
ヨコマツ ツトム | Yokomatsu Tsutomu
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Affiliation and department：
Tokyo University of Pharmacy and Life Science School of Pharmacy
About Tokyo University of Pharmacy and Life Science School of Pharmacy
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Detailed information
Job title：
教授
Research field (1)：
Pharmaceuticals - chemistry and drug development
Research keywords (8)：
化学修飾
, バイオイソスター
, 酵素阻害剤
, 情報伝達
, chemical modification
, bioisostere
, enzyme inhibitor
, transduction
Research theme for competitive and other funds (4)：
酵素阻害剤の創製
含リンバイオアイソスターの合成とその生物活性評価
Development of Reactions mimicking Enzymatic Functions
Synthesis and Biological Evaluation of Bioisosteres containing Phosphorus
MISC (86)：
T Yamagishi, K Fujii, S Shibuya, T Yokomatsu. Asymmetric synthesis of phosphonic acid analogues for acylcarnitine. TETRAHEDRON. 2006. 62. 1. 54-65
T Murano, H Kobayakawa, Y Yuasa, T Yokomatsu, S Shibuya. Improved synthesis of 1,3-propanediol derivatives having a diethoxyphosphoryldifluoroethyl functional group at the 2-position: Application to chemoenzymatic synthesis of novel acyclic nucleotide analogues of adenosine bisphosphates. SYNTHESIS-STUTTGART. 2005. 187-192. 2. 187-192
A practical synthesis of 8-hydroxyacyclovir and 9-(carbomethoxymethyl)guanine, metabolites of acyclovir. Heterocycles. 2005. 65, 1967-1973
M Luic, G Koellner, T Yokomatsu, S Shibuya, A Bzowska. Calf spleen purine-nucleoside phosphorylase: crystal structure of the binary complex with a potent multisubstrate analogue inhibitor. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY. 2004. 60. 1417-1424
Synthesis of chiral -amino--hydroxyphosphonate derivatives from unsaturated phosphonates. Synlett. 2004. 2505-2508
ｍore...
Professional career (2)：
(BLANK)
薬学博士
Association Membership(s) (3)：
有機合成化学協会
, アメリカ化学会(American Chemical Society)
, 日本薬学会
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