Research field (2):
Functional biochemistry
, Applied biochemistry
Research keywords (1):
酵素工学
Research theme for competitive and other funds (8):
2020 - 2023 Development for quantum-theoretical approach by observing hydrogen atom positions in drug target proteins
2016 - 2020 Crystal structure analysis for intermediate in enzymatic reaction by using neutron beam
2012 - 2015 Elucidation of protection strategy for toxicity of D-amino acid in plant
2004 - 2005 Strategy for cold adaptation of enzyme : studies on structure and molecular evolution of cold active alcohol dehydrogenase
2000 - 2002 好冷性酵素の構造と低温での特性に関する研究
1996 - 1997 Structural and functional analysis of bacterial D-amino acid metabolic enzymes to develop their inhibitors
1996 - 1996 バクテリアセルロース生産菌のセルラーゼの構造と機能解析
1991 - 1992 ANALYSIS OF OXIDATIVE FERMENTATION, BIOCHEMICAL AND GENE-TECHNOLOGICAL RECONSTITUTION OF CN-INSENSITIVE RESPIRATORY CHAIN OF ACETIC ACID BACTERIA
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Papers (129):
Fumihito Hasebe, Kazuya Adachi, Kazuya Yamanaka, Tadao Oikawa, Chitose Maruyama, Yoshimitsu Hamano. Constitutive and high gene expression in the diaminopimelate pathway accelerates ε-poly-L-lysine production in Streptomyces albulus. The Journal of antibiotics. 2023. 76. 9. 522-531
Tadao Oikawa, Kouhei Okajima, Kazuya Yamanaka, Shiro Kato. First enzymological characterization of selenocysteine β-lyase from a lactic acid bacterium, Leuconostoc mesenteroides. Amino Acids. 2022
Kazuya Yamanaka, Hibiki Fukumoto, Naoki Yoshimura, Kenji Arakawa, Yasuo Kato, Yoshimitsu Hamano, Tadao Oikawa. Discovery of a Polyamino Acid Antibiotic Solely Comprising l-β-Lysine by Potential Producer Prioritization-Guided Genome Mining. ACS Chemical Biology. 2022. 17. 1. 171-180
山中 一也, 老川 典夫. Molecular and Mechanistic Characterization of PddB, the First PLP-Independent 2,4-Diaminobutyric Acid Racemase Discovered in an Actinobacterial D-Amino Acid Homopolymer Biosynthesis. Frontiers in Microbiology. 2021. 12, 686023