Rchr
J-GLOBAL ID:200901032950554360   Update date: Apr. 03, 2024

Akao Yukihiro

アカオ ユキヒロ | Akao Yukihiro
Affiliation and department:
Job title: 特任教授
Other affiliations (3):
  • 大阪医科大学  医学部   客員教授
  • 連合創薬医療情報研究科  特任教授
  • 工学研究科  教授
Homepage URL  (1): http://www.souyaku.gifu-u.ac.jp/
Research field  (2): Experimental pathology ,  Medical biochemistry
Research keywords  (3): RCK/P54 RNA helicase in cancer ,  phytochemicals in cancer prevention ,  microRNAs in humancancers
Research theme for competitive and other funds  (36):
  • 2019 - 2022 Mechanism of Exosome Production by Heterotrimeric G Protein Signaling
  • 2018 - 2021 Realization of microRNA drug discovery, overcoming intractable cancer through medicine-engineering-pharmacy collaboration
  • 2016 - 2019 The elucidation of biliary and pancreatic tumor's pathobiology through the functional analysis of novel Warburg effect-associated gene PTBP1
  • 2016 - 2019 Investigation of extracellular vesicles as novel biomarker in 4 type gastric cancer patients
  • 2018 - 2019 がん特異的エネルギー代謝を標的にしたRNA創薬
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Papers (363):
  • Soo Takasu, Risa Watanabe, Nobuhiko Sugito, Kohei Morikawa, Akio Iio, Yukihiro Esaka, Yukihiro Akao. Unveiling the vitamin E profile in rice bran extracellular vesicles: evaluation of extraction and preparation methods. Analytical Sciences. 2024
  • Jun Arima, Kohei Taniguchi, Nobuhiko Sugito, Kazuki Heishima, Yoshihisa Tokumaru, Yosuke Inomata, Kazumasa Komura, Tomohito Tanaka, Masa-Aki Shibata, Sang-Woong Lee, et al. Antitumor effects of chemically modified miR-143 lipoplexes in a mouse model of pelvic colorectal cancer via myristoylated alanine-rich C kinase substrate downregulation. Molecular Therapy - Nucleic Acids. 2023. 34. 102079-102079
  • Noriko Miyamoto, Nobuhiko Sugito, Yukio Kitade, Yukihiro Akao. Growth inhibition of RAS-mutated hematopoietic tumor cells using glucose-attached reversibly ionic oligonucleotide-based nanoparticles caging chemically modified microRNA143-3p. Journal of Drug Delivery Science and Technology. 2023. 88. 104902-104902
  • Kazuki Heishima, Nobuhiko Sugito, Chikara Abe, Akihiro Hirata, Hiroki Sakai, Yukihiro Akao. Targeting microRNA-145-mediated progressive phenotypes of early bladder cancer in a molecularly defined in vivo model. Molecular Therapy - Nucleic Acids. 2023. 33. 960-982
  • Tomohiro Itoh, Tomomi Degawa, Yuko Ito, Yukihiro Akao, Nobuaki Okumura. Role of Royal Jelly Treated Adipose-Derived Stem Cell-Extracellular Vesicles on Fibroblast Proliferation, Migration, and Collagen Production. Dermatologic Therapy. 2023. 2023. 1-21
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MISC (119):
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Patents (6):
  • 健康食品
  • 癌細胞のアポトーシス誘導剤、その製造方法、それを有効成分とする抗癌剤、食品製剤及び化粧品
  • RNA修飾蛋白、蛋白合成促進剤、遺伝子治療薬及び癌治療薬
  • 癌治療薬及び癌予防薬
  • 癌治療薬
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Education (2):
  • - 1978 Osaka Medical College Faculty of Medicine Medicine
  • - 1978 Osaka Medical College Faculty of Medicine Division of Medicine
Professional career (1):
  • Doctor (Nagoya University)
Work history (16):
  • 2018/04 - 現在 岐阜大学大学院連合創薬医療情報研究科 特任教授
  • 2009/04 - 2018/03 岐阜大学大学院連合創薬医療情報研究科 教授
  • 1998/04 - 2009/03 (財)岐阜県国際バイオ研究所 遺伝子診断研究部 部長
  • 1997/04 - 1998/03 (財)岐阜県国際バイオ研究所 遺伝子診断研究部 副部長
  • 1996 - 1998 Vice-Manager of Gifu International Institute of Biotechnology
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Committee career (2):
  • 2018/04 - 現在 日本核酸医薬学会 評議員
  • 2017/06 - 2020/06 日本がん分子標的治療学会 日本がん分子標的治療学会評議員
Awards (3):
  • 2004/09/15 - 日本白血病研究基金 一般研究賞
  • 1992 - Young Researcher Prize of Japanese Society of Hematology
  • 1992 - 日本血液学会奨励賞
Association Membership(s) (10):
日本核酸医薬学会 ,  日本薬学会 ,  日本分子生物学会 ,  日本癌学会 評議員 ,  日本RNA学会 ,  日本Cell Death学会 ,  American Association of Cancer Research ,  Japanese Society of Cancer Research ,  米国癌学会 ,  日本癌学会
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