Rchr
J-GLOBAL ID：200901033757880370   Update date: Apr. 17, 2024

Shiro Yoshitsugu

シロ ヨシツグ | Shiro Yoshitsugu
Affiliation and department：
兵庫県立大学 生命理学研究科 生命科学専攻

About 兵庫県立大学 生命理学研究科 生命科学専攻


Job title： 教授
Research field  (5)： Molecular biology ,  Functional biochemistry ,  Structural biochemistry ,  Polymer chemistry ,  Basic physical chemistry
Research keywords  (10)： Iron Transporters ,  Nitric Oxide Reducatse ,  センサータンパク質 ,  酸素添加酵素 ,  チトクロムP450 ,  金属酵素 ,  Sensor proteins ,  Oxygenases ,  Cytochrome P450 ,  Metal-binding enzymes
Research theme for competitive and other funds  (36)：
  • 2019 - 2024 Integrated Biometal Science: Research to Explore Dynamics of Metals in Cellular System
  • 2019 - 2024 Strctural and Functional Dynamics on Proteins Related to Biometal Dynamics
  • 2019 - 2023 Structural Dynamics of Nitric Oxide Reductases Srudied by Time-Resolved Techniques
  • 2014 - 2019 Molecular Science of NO Dyanmics in Biological System
  • 2015 - 2018 Development of time-resolved spectroscopic systems with micro-flow devices and their application to the molecular mechanism of ABC transporters
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Papers (290)：
  • Hanae Takeda, Kanji Shimba, Masaki Horitani, Tetsunari Kimura, Takashi Nomura, Minoru Kubo, Yoshitsugu Shiro, Takehiko Tosha. Trapping of a Mononitrosyl Nonheme Intermediate of Nitric Oxide Reductase by Cryo-Photolysis of Caged Nitric Oxide. The journal of physical chemistry. B. 2023. 127. 4. 846-854
  • Yuya Nishida, Sachiko Yanagisawa, Rikuri Morita, Hideki Shigematsu, Kyoko Shinzawa-Itoh, Hitomi Yuki, Satoshi Ogasawara, Ken Shimuta, Takashi Iwamoto, Chisa Nakabayashi, et al. Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases. Nature Communications. 2022. 13. 1. 7591
  • 浦 敦人, 簗取 いずみ, 城 宜嗣, 澤井 仁美. 細胞内鉄輸送タンパク質PCBP1における鉄イオンの結合と輸送の分子メカニズム. 日本生化学会大会プログラム・講演要旨集. 2022. 95回. 2T05a-05
  • 浦 敦人, 簗取 いずみ, 城 宜嗣, 澤井 仁美. 細胞内鉄輸送タンパク質PCBP1における鉄イオンの結合と輸送の分子メカニズム. 日本生化学会大会プログラム・講演要旨集. 2022. 95回. 2T05a-05
  • Hiro Nakamura, Tamao Hisano, Md Mahfuzur Rahman, Takehiko Tosha, Mikako Shirouzu, Yoshitsugu Shiro. Structural basis for heme detoxification by an ATP-binding cassette-type efflux pump in gram-positive pathogenic bacteria. Proceedings of the National Academy of Sciences of the United States of America. 2022. 119. 27. e2123385119
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MISC (186)：
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Education (2)：
  • 1980 - 1985 Kyoto University Graduate School of Engineering
  • 1976 - 1980 Kyoto University Faculty of Engineering Department of Hydrocarbon Chemistry
Professional career (1)：
  • Ph.D. (Doctor of Engineering)
Work history (15)：
  • 2015/04 - 現在 University of Hyogo Graduate School of Life Science Professor
  • 2016/04 - 2018/03 Kyushu University Institute for Materials Chemistry and Engineering
  • 2000/04 - 2015/03 理化学研究所 播磨研究所 生体物理化学研究室 主任研究員
  • 1999/04 - 2015/03 姫路工業大学(現 兵庫県立大学)大学院 生命理学研究科 連携大学院 教授
  • 2006/04 - 2013/03 大阪大学大学院 理学研究科 連携大学院 教授
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Committee career (2)：
  • 2018/06 - 2020/06 Vice President
  • 2019/06 - 2019/06 Chair
Awards (6)：
  • 2021/01 - The Chemical Scoiety of Japan CSJ Award Molecular Structural and FUnctional Studies on Iron-Related Proteins
  • 2020/11 - Hyogo Hyogo Scientific Excellence Award
  • 2020/10 - University of Hyogo 研究活動教員表彰 最優秀研究活動賞
  • 2019/09 - JSCC (Japan Society of Coordination Chemistry) JSCC Contribution Awards Functional Studies on Hemoproteins Based on Their Molecular Structures: New Era of Integrated Biometal Sciences
  • 2013/03 - RIKEN 理化学研究所 重要業績表彰
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Association Membership(s) (8)：
日本蛋白質学会 ,  日本生物物理学会 ,  日本生化学会 ,  日本化学会 ,  The Protein Science Society of Japan ,  The Biophysical Society of Japan ,  The Japanese Biochemical Society ,  The Chemical Society of Japan
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