Rchr
J-GLOBAL ID:200901034237809661   Update date: Apr. 07, 2024

Shimizu Takeshi

Shimizu Takeshi
Homepage URL  (1): http://www.med.hirosaki-u.ac.jp/~bgb/top/index.html
Research field  (3): Molecular biology ,  Medical biochemistry ,  Pathobiochemistry
Research keywords  (6): Molecular Biology ,  Biochemistry ,  癌 ,  バイオテクノロジー ,  Cancer ,  Biotechnology
Research theme for competitive and other funds  (3):
  • 2022 - 2025 ORNi-PCR法によるリンゴ黒星病菌における防除剤耐性変異株の高速検出法の開発
  • 2013 - 2015 The physiological role of autophagy in the intestinal epithelial cells
  • 2004 - 自然発生腫瘍識別のための新規分子マーカーの開発
Papers (44):
  • Takeshi Shimizu, Toshitsugu Fujita, Hodaka Fujii. Oligoribonucleotide interference-PCR: principles and applications. Biology Methods and Protocols. 2022. 7. 1. bpac010
  • Takeshi Shimizu, Toshitsugu Fujita, Sakie Fukushi, Yuri Horino, Hodaka Fujii. Discrimination of CpG Methylation Status and Nucleotide Differences in Tissue Specimen DNA by Oligoribonucleotide Interference-PCR. International journal of molecular sciences. 2020. 21. 14
  • Wakasa Y, Kimura N, Yamada T, Shimizu T, Hakamada K, Tsuchida S. Delay in hepatocyte proliferation and prostaglandin D2 synthase expression for cholestasis due to endotoxin during partial hepatectomy in rats. Molecular Medicine Reports. 2019. 20. 5. 4367-4375
  • Naoki Nanashima, Kayo Horie, Toshiyuki Yamada, Takeshi Shimizu, Shigeki Tsuchida. Hair keratin KRT81 is expressed in normal and breast cancer cells and contributes to their invasiveness. ONCOLOGY REPORTS. 2017. 37. 5. 2964-2970
  • Naoki Nanashima, Toshiyuki Yamada, Takeshi Shimizu, Shigeki Tsuchida. Involvement of Clustered Genes in Mammalian Functions: Their Relation in a Rat Mutant Strain. JOURNAL OF MOLECULAR EVOLUTION. 2017. 84. 4. 159-161
more...
MISC (10):
  • 清水武史, 馬場啓介, 藤田敏次, 藤井穂高. Detection of single-nucleotide mutations of cancer driver genes and polymorphisms in tissue specimens by ORNi-PCR. 日本癌学会学術総会抄録集(Web). 2020. 79th
  • 澤野 武行, 三浦 卓也, 工藤 大輔, 清水 武史, 七島 直樹, 山田 俊幸, 土田 成紀, 袴田 健一. OP-002-1 CPT-11によるSDラット肝のsteatosis誘発とそれに先行するKupffer細胞の減少 : CPT-11肝障害の動物モデル(OP-002 肝 基礎-2,一般演題,第114回日本外科学会定期学術集会). 日本外科学会雑誌. 2014. 115. 2. 314
  • Miura Takuya, Kimura Norihisa, Yamada Toshiyuki, Shimizu Takeshi, Nanashima Naoki, Yamana Daisuke, Hakamada Kenichi, Tsuchida Shigeki. Sustained Repression and Translocation of NTCP and Expression of MRP4 for Cholestasis after Rat 90% Partial Hepatectomy [Innovation in Transplant and Regenerative Medicine. The 13th Meeting of Hirosaki International Forum of Medical Science. Communication Center of Hirosaki University School of Medicine. September 9, 2011, Hirosaki, Japan]. The Hirosaki medical journal. 2013. 64. S99-S106
  • Yamada Toshiyuki, Nanashima Naoki, Shimizu Takeshi, Tsuchida Shigeki. Differentiation Inhibition of Regulatory T Cells in Hirosaki Hairless Rat Due to Deletion of the LY49 Family Genes Expressed in thymic T Cells and Dendritic Cells [Innovation in Transplant and Regenerative Medicine. The 13th Meeting of Hirosaki International Forum of Medical Science. Communication Center of Hirosaki University School of Medicine. September 9, 2011, Hirosaki, Japan]. The Hirosaki medical journal. 2013. 64. S65-S69
  • Takuya Miura, Norihisa Kimura, Daisuke Yamana, Kenichi Hakamada, Shigeki Tsuchida, Toshiyuki Yamada, Takeshi Shimizu, Naoki Nanashima. Reply to: "Transient elevation of serum bile salts after partial hepatectomy is due to metabolic overload and not to cholestasis". JOURNAL OF HEPATOLOGY. 2012. 56. 3. 744-745
more...
Lectures and oral presentations  (1):
  • Development of a rapid detection method for fungicide-resistant mutant strains of apple scab fungus using ORNi-PCR method
    (2023)
Professional career (2):
  • 博士(農学) (岩手大学)
  • 修士(農学) (弘前大学)
Work history (4):
  • 2023/04 - 現在 Hirosaki University Institute for the Promotion of Research and Innovation
  • 2004/05 - 2023/03 Hirosaki University Department of Biochemistry and Genome Biology, Graduate School of Medicine Assistant Professor
  • 2001/05 - 2004/04 Iwate Biotechnology Research Center Department of Genomics and Breeding Researcher
  • 1999/04 - 2001/04 Bio-oriented Technology Research Advancement Institution Researcher
Awards (2):
  • 2023/05 - Intelligent Cosmos Academic Foundation 22nd Intelligent Cosmos Encouragement Award
  • 2019/08 - 弘前大学 教育に関して優れた業績を上げた教員
Association Membership(s) (2):
THE JAPANESE CANCER ASSOCIATION ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
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