Rchr
J-GLOBAL ID：200901034937657609
Update date: Feb. 01, 2024
Yamasaki Kazuhiko
ヤマサキ カズヒコ | Yamasaki Kazuhiko
Affiliation and department：
Job title：
Senior Research Scientist
Homepage URL (1)：
http://www.aist.go.jp/RESEARCHERDB/cgi-bin/worker_detail.cgi?call=namae&rw_id=K61785063
Research field (1)：
Structural biochemistry
Research keywords (5)：
分子認識 生体高分子 立体構造 核磁気共鳴 創薬開発
, Nuclear Magnetic Resonance
, Three-dimensional structure
, Biomolecule
, Molecular Recognition
Research theme for competitive and other funds (10)：
- 2019 - 2021 Structural biology of Trypanosoma brucei GPI phospholipase c and the development of selective inhibitors against it
- 2018 - 2021 Development of novel probes for a glycan for medicinal technology
- 2018 - 2020 Target determination and exploratory research for discovery of new drugs against Chagas disease
- 2015 - 2017 Creation of novel DNA ligands with potent analgesic action against MOR opioid receptor and elucidation of molecular mechanisms.
- 2013 - 2017 Theoretical investigation of reaction fields of biological macromolecular systems based on quantum sciences and mathematical informatics
- 2012 - 2015 Development of nucleic acids therapeutics against multiple domains of transcription factor SATB1
- 2012 - 2013 PLGA結合型核酸の研究開発
- 2009 - 2011 高温超伝導材料を利用した次世代NMR技術の開発
- 2008 - 2011 CUT-homeodomain転写因子のDNA結合におけるドメイン間相違と協同性
- 2005 - 2006 Structural biology of transcriptional regulation by SATB1 that binds to matrix attachment region of DNA
Show all
Papers (78)：
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Kazuhiko Yamasaki, Naruhiko Adachi, Mya Myat Ngwe Tun, Akihito Ikeda, Toshio Moriya, Masato Kawasaki, Tomoko Yamasaki, Tomomi Kubota, Izuru Nagashima, Hiroki Shimizu, et al. Core fucose-specific Pholiota squarrosa lectin ( PhoSL ) as a potent broad-spectrum inhibitor of SARS-CoV -2 infection. The FEBS Journal. 2022. 290. 2. 412-427
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Nobuhiro Matsumoto, Nobuyasu Itoh, Kazuhiko Yamasaki. Absolute Quantification of Pure Free Radical Reagents by Combination of the Effective Magnetic Moment Method and Quantitative Electron Paramagnetic Resonance Method. Analytical Chemistry. 2022
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Kazuhiko Yamasaki. Old yellow enzyme of a novel fungi-specific class. The FEBS Journal. 2022
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Mohammed Auwal Ibrahim, Tomoko Yamasaki, Koji Furukawa, Kazuhiko Yamasaki. Fragment-Based Drug Discovery for Trypanosoma brucei Glycosylphosphatidylinositol-Specific Phospholipase C through Biochemical and WaterLOGSY-NMR Methods. The Journal of Biochemistry. 2022
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Kazuhiko Yamasaki, Tomoko Yamasaki, Masaharu Takahashi, Hiroto Suematsu. A mixing microfluidic chip for real-time NMR monitoring of macromolecular reactions. The Journal of Biochemistry. 2021
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MISC (1)：
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山崎和彦, 山崎和彦, 木川隆則, 木川隆則, 渡部暁, 山崎智子, 井上真, 関原明, 篠崎一雄, 横山茂之, et al. 残余双極子相互作用を用いたタンパク質・DNA複合体立体構造の精密化. Abstracts. Annual Meeting of the NMR Society of Japan. 2009. 48th
Patents (7)：
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スギタケレクチン及び/又はその変異ペプチドを含むウイルス感染症の治療用又は診断用医薬組成物
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NMR測定用混合マイクロチップ
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マイクロベシクルに対する核酸アプタマー
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NMR検出を用いた酵素活性の測定方法または酵素活性阻害剤の評価方法
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微小タンパク質を内包する分子ライブラリ
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Books (1)：
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Plant Transcription Factors: Evolutionary, Structural and Functional Aspects
Elsevier 2015
Education (3)：
- 1988 - 1993 東京大学 大学院 理学系研究科 生物化学専攻
- 1986 - 1988 The University of Tokyo Faculty of Science Department of Biophysics and Biochemistry
- 1984 - 1986 The University of Tokyo College of Arts and Sciences
Professional career (1)：
Work history (6)：
Committee career (4)：
- 2023/11 - 現在 日本生化学会 代議員
- 2018/01 - 現在 日本生化学会 関東支部 幹事
- 2019/09 - 2021/11 日本生化学会 代議員
- 2021/07 - 2021/09 日本生化学会 選挙管理委員
Association Membership(s) (2)：
THE NUCLEAR MAGNETIC RESONANCE SOCIETY OF JAPAN
, 日本生化学会
