Koichi Matsuo

マツオコウイチ | Koichi Matsuo

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www.matsuo-lab.com/

Research field (2)： Anatomy , Cell biology

Research keywords (8)： cell chirality , Left-right symmetry , osteoblast , osteocyte , bone remodeling , bone modeling , auditory ossicles , osteoclast

Research theme for competitive and other funds (19)：

2021 - 2025 Understanding the cellular basis of left-right symmetry in the skeleton
2021 - 2024 Building a versatile medical test system in a pandemic
2021 - 2023 Construction technique for a bilateral skeleton composed of homochiral building blocks
2017 - 2021 Osteogenic capillaries - new aspect of endochondral ossification
2014 - 2016 Elucidating mechanisms of altered bone matrix mineralization

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Papers (123)：

Junna Oba, Masako Toriya, Yoshifumi Uwamino, Koichi Matsuo. Using a Systems Engineering Approach to Build a PCR Testing System at a Medical School During the COVID-19 Pandemic. Risk Management and Healthcare Policy. 2024. Volume 17. 649-662
Takahito Iga, Hiroshi Kobayashi, Dai Kusumoto, Tsukasa Sanosaka, Nobuyuki Fujita, Ikue Tai-Nagara, Tomofumi Ando, Tomoko Takahashi, Koichi Matsuo, Katsuto Hozumi, et al. Spatial heterogeneity of bone marrow endothelial cells unveils a distinct subtype in the epiphysis. Nature Cell Biology. 2023
Kenji Tanaka, Shuma Ohara, Tadaaki Matsuzaka, Aira Matsugaki, Takuya Ishimoto, Ryosuke Ozasa, Yukiko Kuroda, Koichi Matsuo, Takayoshi Nakano. Quantitative Threshold Determination of Auditory Brainstem Responses in Mouse Models. International Journal of Molecular Sciences. 2023. 24. 14
Takashi Nakamura, Sayako Honda, Shinichirou Ito, Toshihide Mizoguchi, Takehiro Yamamoto, Masataka Kasahara, Yasuaki Kabe, Koichi Matsuo, Makoto Suematsu. Generation of bicistronic Dmp1-Cre knock-in mice using a self-cleaving 2A peptide. Journal of bone and mineral metabolism. 2023
Yoshikazu Kuboi, Yukiko Kuroda, Masayoshi Ohkuro, Sotaro Motoi, Yoshiya Tomimori, Hisataka Yasuda, Nobuyuki Yasuda, Toshio Imai, Koichi Matsuo. The Fractalkine-CX3CR1 Axis Regulates Non-inflammatory Osteoclastogenesis by Enhancing Precursor Cell Survival. JBMR Plus. 2022

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MISC (37)：

副甲状腺ホルモンPTHは軟骨内骨化の必須条件である破軟骨細胞による石灰化軟骨吸収作用を抑制する. SPring-8/SACLA Research Report. 2020. 8. 476-479
Lijuan Zhao, Atsushi Arai, Nobuyuki Udagawa, Kanji Horibe, Miroku Hara, Daisuke Nishida, Akihiro Hosoya, Rinya Masuko, Koji Okabe, Masashi Shin, et al. Odontoblast Cell Death Drives Stem Cell-Independent Cell-Rich Zone-Derived Dental Tissue Regeneration. SSRN Electronic Journal. 2020
楊孟雨, 溝口利英, 宇田川信之, 松尾光一, 小守壽文, 森石武史, 小林泰浩, 高橋直之. PTHアナボリック作用に対する骨髄間葉系幹細胞の寄与. 日本骨代謝学会学術集会プログラム抄録集. 2016. 34th. 193-193
3D Visualization of Osteogenic Capillaries in Mineralized Bone Tissue by Integrating Micro-CT with Light Sheet Fluorescence Microscopy Imaging. Microscopy. 2016. 51. 2. 88-93
Matsuo Koichi. Bone Cell Biology Assessed by Microscopic Approach. Regulation of bone mineralization through the osteocyte lacuno-canalicular network. Clinical calcium. 2015. 25. 10. 1461-1466

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Patents (1)：

炎症性疾患の検出並びに炎症性疾患の予防又は治療用組成物

Lectures and oral presentations (125)：

Left-right asymmetry in calvarial mineralization by osteoblasts.
(2023)
ホモキラルな骨芽細胞が左右対称な骨格を形作る
(第40回日本骨代謝学会学術集会 2022)
破骨細胞誘導因子による脊索腫細胞の破骨細胞様変化
(第40回日本骨代謝学会学術集会 2022)
筋肉の発達に応答した皮質骨形態変化は「内向きトランスペアリング」によって生み出される
(第42回日本骨形態計測学会 2022)
Talbot and Zernike Phase-Contrast Tomographic X-ray Microscopy of Muscle Cells in Ascidian Tadpole Larvae.
(15th International Conference on X-ray Microscopy (XRM2022) 2022)

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Education (2)：

1986 - 1990 Keio University Graduate School of Medicine
1980 - 1986 Keio University School of Medicine

Professional career (2)：

博士(医学) (慶應義塾)
M.D., Ph.D. (Keio University)

Work history (9)：

2009/10 - 現在 Director of the Center for Integrated Medical Research
2009/06 - 現在 Keio University School of Medicine Laboratory of Cell and Tissue Biology Professor
2007/04 - 2009/05 Keio University School of Medicine Department of Microbiology and Immunology Associate Professor
2002/04 - 2007/03 Associate Professor, School of Medicine, Keio University Department of Microbiology and Immunology Associate professor
2001/04 - 2002/03 Chief, National Institute for Longevity Sciences Chief

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Awards (3)：

2014/07/25 - Japanese Society for Bone and Mineral Research Distinguished Scientist Award
2003/06/12 - Keio University School of Medicine Kitasato Award
1997/09/10 - American Society for Bone and Mineral Research Young Investigator Award

Association Membership(s) (3)：

International Bone and Mineral Metabolism (IBMS) , American Society for Bone and Mineral Research (ASBMR) , The Japanese Society for Bone and Mineral Research

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