Rchr
J-GLOBAL ID:200901036346887896   Update date: Apr. 17, 2024

Kawada Norifumi

カワダ ノリフミ | Kawada Norifumi
Affiliation and department:
Job title: Professor
Research field  (2): Gastroenterology ,  Gastroenterology
Research keywords  (1): Gastroenterology
Research theme for competitive and other funds  (40):
  • 2022 - 2025 肝細胞のがん化における細胞間相互作用を介した星細胞の役割
  • 2021 - 2024 B型肝炎の治療抵抗性および病態進展における免疫チェックポイント分子の関与
  • 2021 - 2024 Cytoglobin (CYGB)-overexpression and targeted demethylation of CYGB promoter impair liver and pancreatic tumor growth
  • 2020 - 2023 Basic study for developing NASH therapeutic drugs by using a small molecule derived from the cellular slime mold serving as a lead compound
  • 2019 - 2023 地元大阪の印刷所労働者胆管がん組織を使ったがん遺伝子の探索:創薬基盤の構築
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Papers (324):
  • Hanh Vinh Ngo, Thuy Thi Thanh Le, Hieu Ngoc Vu, Hai Hoang, Hiroko Ikenaga, Misako Sato-Matsubara, Sawako Uchida-Kobayashi, Hayato Urushima, Khanh Van Nguyen, Ha Thi Nguyen, et al. Poorly Differentiated Hepatocellular Carcinoma Cells Avoid Apoptosis by Interacting with T Cells via CD40-CD40L Linkage. The American journal of pathology. 2024
  • Etsushi Kawamura, Tsutomu Matsubara, Norifumi Kawada. New Era of Immune-Based Therapy in Intrahepatic Cholangiocarcinoma. Cancers. 2023. 15. 15
  • Issei Saeki, Yutaka Suehiro, Yurika Yamauchi, Tomomi Hoshida, Norikazu Tanabe, Takashi Oono, Daiki Kawamoto, Tatsuro Nishimura, Toshihiko Matsumoto, Tsuyoshi Ishikawa, et al. Methylated SEPT9 assay-based liquid biopsy as a biomarker in molecular targeted agent-treated hepatocellular carcinoma. Hepatology International. 2023
  • Yoshinari Matsumoto, Hideki Fujii, Mika Harima, Haruna Okamura, Yoshimi Yukawa-Muto, Naoshi Odagiri, Hiroyuki Motoyama, Kohei Kotani, Ritsuzo Kozuka, Etsushi Kawamura, et al. Severity of Liver Fibrosis Is Associated with the Japanese Diet Pattern and Skeletal Muscle Mass in Patients with Nonalcoholic Fatty Liver Disease. Nutrients. 2023. 15. 5. 1175-1175
  • Naoshi Odagiri, Akihiro Tamori, Kohei Kotani, Hiroyuki Motoyama, Etsushi Kawamura, Atsushi Hagihara, Hideki Fujii, Sawako Uchida-Kobayashi, Masaru Enomoto, Norifumi Kawada. A case of hepatocellular carcinoma with "pseudoprogression" followed by complete response to atezolizumab plus bevacizumab. Clinical journal of gastroenterology. 2023
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MISC (179):
  • Truong Huu Hoang, 松原 三佐子, 河田 則文. 肝類洞内皮細胞の細胞内ギャップ形成はがん細胞の肝転移能力を促進する(Intracellular gap formation of the liver sinusoidal endothelial cells facilitates the liver metastasis ability of cancer cell). 日本消化器病学会雑誌. 2021. 118. 臨増総会. A390-A390
  • 湯川 芳美, 打田 佐和子, 小谷 晃平, 小田桐 直志, 榎本 大, 河田 則文. C型肝炎ウイルス排除後の門脈圧亢進症に対する肝弾性度測定の臨床的有用性. 超音波医学. 2020. 47. Suppl. S273-S273
  • 小田桐 直志, 榎本 大, 打田 佐和子, 河田 則文. 消化器癌化学療法の進歩と課題 肝細胞癌に対するソラフェニブまたはレンバチニブ治療中の血漿可溶性免疫チェックポイント蛋白の変化. 日本消化器病学会近畿支部例会プログラム・抄録集. 2020. 113回. 54-54
  • 小田桐 直志, 元山 宏行, 河田 則文. 【肝疾患の病態生理と新規治療法を巡る基礎的研究の動向】肝線維化の機序と新規治療. 消化器・肝臓内科. 2020. 7. 6. 514-521
  • 小田桐 直志, 松原 勤, 河田 則文. 肝疾患と微小環境 加齢関連肝疾患における肝星細胞の理解. 肝臓. 2020. 61. Suppl.1. A50-A50
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Lectures and oral presentations  (23):
  • Interaction between CD4+T cells and tumor cells in hepatocellular carcinoma microenvironment.
    (2021)
  • Novel Anti-Fibrotic Function of Neuroglobin in vitro and in vivo
    (2021)
  • Cytoglobin欠損マウスの肝星細胞に由来する一酸化窒素は肝細胞のミトコンドリア機能障害を引き起こす
    (第35回 肝類洞壁細胞研究会 2021)
  • 6. Anti-fibrotic Capacity of Extracellular Globins via Scavenging ROS and Promoting MMP-1 Secretion.
    (American Association for the Study of Liver Diseases (AASLD) 2021)
  • Investigation of;CYGB;promoter methylation in hepatocellular carcinoma;
    (American Association for the Study of Liver Diseases (AASLD) 2021)
more...
Education (1):
  • - 1991 Osaka City University Graduate School, Division of Medicine
Professional career (2):
  • 博士(医学)
  • Doctor of Medicine
Work history (1):
  • 1994/10/01 - 現在 Osaka City University Graduate School of Medicine Clinical Medicine Course Professor
Awards (5):
  • 2012/11 - 大阪市立大学学友会賞
  • 2012 - バイオビジネスアワードJAPANバイオ先端知賞
  • 2002 - Karl von Kuppfer Prize
  • 1994 - 日本肝臓学会研究奨励賞
  • 1991 - 大阪市医学会市長賞
Association Membership(s) (9):
EUROPEAN ASSOCIATION FOR THE STUDY OF THE LIVER ,  米国消化器病学会 ,  米国肝臓学会 ,  日本生化学会 ,  日本内科学会 ,  日本肝臓学会 ,  日本消化器類学会 ,  日本門脈圧亢進症学会 ,  日本消化器病学会
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