Rchr
J-GLOBAL ID:200901036459755015
Update date: Jul. 18, 2022
Ishimi Yukio
イシミ ユキオ | Ishimi Yukio
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Research field (1):
Molecular biology
Research keywords (1):
DNA replication, MCM proteins, DNA helicase, DNA replication checkpoint system, human proteins involved in DNA replication
Research theme for competitive and other funds (3):
2014 - 2017 MCMを中心としたDNA複製因子の集合と機能抑制機構の解明
2011 - 2013 DNA複製フォークでの分子集合と複製ヘリカーゼの役割の解明
2005 - 2008 MCMヘリカーゼ機能発現調節機構の解明
Papers (32):
Wang, X, Ishimi, Y. Function of the amino-terminal region of human MCM4 in helicase activity. J. Biochem. 2018. 164. 449-460
Tsuji, M, Tanaka, T, Nagashima, R, Sagisaka, Y, Tosen, Y, Nishide, Y, Ishimi, Y, ishimi, Y. Effect of daidzein and equal on DNA replication in MCF-7 cells. J. Biochem. 2018. 163. 371-380
Ruriko Tatsumi, Yukio Ishimi. An MCM4 mutation detected in cancer cells affects MCM4/6/7 complex formation. JOURNAL OF BIOCHEMISTRY. 2017. 161. 3. 259-268
Hosoi, A, Sakairi, T, Ishimi, Y. Binding of MCM-interacting proteins to ATP-binding site in MCM6. Research Reports in Biology. 2016. 7. 31-40
Yukio Ishimi, Daiki Irie. G364R mutation of MCM4 detected in human skin cancer cells affects DNA helicase activity of MCM4/6/7 complex. JOURNAL OF BIOCHEMISTRY. 2015. 157. 6. 561-569
more...
MISC (1):
Ishimi, Y. Regulation of MCM2-7 helicase. Genes Genet. System. 2018. 93. 125-133
Lectures and oral presentations (15):
MCM相互作用因子はMCM6のATP結合部位に結合する
(第39回日本分子生物学会年会 2016)
MCMヘリカーゼの保存性と多様性
(日本進化学会第18回東京大会 2016)
ヒトMCM-BPタンパク質の機能解析
(日本分子生物学会年会 2009)
乳がんを引き起こすMCM4タンパク質変異の解析
(日本分子生物学会年会 2009)
ヒトRPAに直接的に相互作用するタンパク質の同定
(日本分子生物学会年会 2009)
more...
Professional career (1):
薬学博士 (東京大学)
Work history (4):
2004/10 - Prof. Faculty of Science, Ibaraki University
1988/09 - 2004/09 member, Mitsubishi Kagaku Institute of Life Sciences
1983/07 - 1988/08 assistant professor, Faculty of Pharmaceutical Sciences, University of Tokyo
Ibaraki University Graduate School of Science and Engineering (Science), Department of Science (Biological Sciences Course) Professor
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